Results 121 to 130 of about 187,537 (165)

Protection by Antioxidant Flavonoids

Free Radical Biology and Medicine, 2014
Reactive oxygen species (ROS) react with any cellular component leading to oxidative damage. As an adaptive response to ROS, cells activate Nrf2 which enforces the endogenous antioxidant defense. Exogenous antioxidants directly neutralize the ROS and prevent the oxidative damage. This protection against ROS might backfire, because the adaptive response
Guido R. Haenen, Aalt Bast
openaire   +1 more source

Diverse antioxidants protect against acetaminophen hepatotoxicity

Journal of Biochemical and Molecular Toxicology, 2005
The reactive oxygen species-sensitive transcription nuclear factor-kappaB (NF-kappaB) plays a pivotal role in the development of acetaminophen (APAP) hepatotoxicity. We investigated the efficacy of a diverse series of antioxidants in preventing APAP-induced hepatotoxicity.
Helieh S, Oz, Craig J, McClain, Herbert T, Nagasawa, Mukunda B, Ray, Willem J S, de Villiers, Theresa S, Chen   +5 more
openaire   +2 more sources

Antioxidants and endothelium protection

Atherosclerosis, 2005
The endothelium is a complex organ system that controls the homeostasis of the vasculature by integrating signals between the vascular wall and the vessel lumen. Under physiological conditions, it maintains a normal vascular tone and blood fluidity by elaborating a variety of factors, such as nitric oxide, prostacyclin and endothelin.
openaire   +2 more sources

Antioxidant Protective Effects of Mushroom Metabolites

Current Topics in Medicinal Chemistry, 2013
Global industrialization and agricultural development are related to the release of various pollutants into the environment including huge amounts of free radicals, which are associated with the occurrence of various destructive diseases and disorders.
Stajić, Mirjana, Vukojević, Jelena, Knezević, Aleksandar, Duletić-Lausević, Sonja, Milovanović, Ivan   +4 more
openaire   +3 more sources

Antioxidants: Protection Versus Apoptosis

2000
Tissue homeostasis is tightly regulated by both proliferation and cell death. These processes are crucial in embryogenesis during the development of the central nervous system (Rcaff 1993; Narayanan 1997) and the development (Von Boehmer 1992) and function of the immune system (Cohen And Duke 1992).
Y. Delneste, E. Roelandts, J.-Y. Bonnefoy, P. Jeannin   +3 more
openaire   +1 more source

[Antioxidants in liver protection].

Orvosi hetilap, 2004
Great importance has been attributed to antioxidants in the prevention and treatment of conditions associated with oxidative stress for many years. At the same time the antioxidants are free radicals themselves, and they can exert prooxidant activity depending on the concentration.
Krisztina, Hagymási, Anna, Blázovics
openaire   +1 more source

Antioxidant nutrients protect against cyclosporine A nephrotoxicity

Toxicology, 2003
The immunosuppressive drug cyclosporine A (CsA) has been successfully used in several diseases with immunological basis and in transplant patients. Nephrotoxicity is the main secondary effect of CsA treatment. Although the mechanisms of nephrotoxitity are not completely defined, there is evidence that suggests the role of reactive oxygen species (ROS ...
T, Parra Cid, J R, Conejo García, F, Carballo Alvarez, G, de Arriba   +3 more
openaire   +2 more sources

Antioxidant protective mechanisms in muscle

2021
This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
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Diethyldithiocarbamate Protection Against Cisplatin Nephrotoxicity: Antioxidant System

Drug and Chemical Toxicology, 1995
This investigation elucidates the role of antioxidant system in cisplatin induced nephrotoxicity and the nephroprotection with diethyldithiocarbamate (DDTC). Male Wistar rats were injected with 1) cisplatin; 2) cisplatin+DDTC and 3) vehicle control.
S M, Somani, R, Ravi, L P, Rybak
openaire   +2 more sources

Trolox‐derivative antioxidant protects against methanol‐induced damage

Fundamental & Clinical Pharmacology, 1997
Summary— This paper reports data on the effect of a new antioxidant, U‐83836E, on the lipid peroxidation and antioxidant status of liver, red blood cells (RBCs) and blood serum of rats intoxicated with methanol (3.0 g/kg body weight). Methanol administration slightly increased the levels of peroxidation products in the liver, and markedly increased ...
E, Skrzydlewska, R, Farbiszewski
openaire   +2 more sources