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Idebenone: When an antioxidant is not an antioxidant
Idebenone is a well described drug that was initially developed against dementia. The current literature widely portrays this molecule as a potent antioxidant and CoQ10 analogue. While numerous papers seem to support this view, a closer look indicates that the pharmacokinetics of idebenone do not support these claims.
Nuri Gueven +3 more
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Flavonoids display a broad range of health-promoting bioactivities. Among these, their capacity to act as antioxidants has remained most prominent. The canonical reactive oxygen species (ROS)-scavenging mode of the antioxidant action of flavonoids relies
Hernan Speisky +3 more
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The term "scavengome" refers to the chemical space of all the metabolites that may be formed from an antioxidant upon scavenging reactive oxygen or nitrogen species (ROS/RNS). This chemical space covers a wide variety of free radical metabolites with drug discovery potential.
Attila Hunyadi +3 more
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Cocoa beans are the seeds of the tropical tree Theobroma cacao L [...]
Joanna Oracz, Dorota Żyżelewicz
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NADPH is an indispensable cofactor in a wide range of physiological processes that is generated by a family of NADPH dehydrogenases, of which the NADP-dependent malic enzyme (NADP-ME) is a member.
Jorge Taboada +4 more
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Article [1] was published on 26 September 2012. In order to update the spelling of the second author’s name—“Divine N. Akumo” was written as “Divine Akumo”, it was updated a few days after publication and prior to issue release. [...]
Antioxidants Editorial Office
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Heather (Calluna vulgaris (L.) Hull.) is noted for a diverse chemical composition and a broad range of biological activity. The current study was aimed at monitoring changes in the accumulation of certain groups of phenolic compounds in various organs of
Victoria Chepel +2 more
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Nitric oxide (NO) is a free radical which modulates protein function and gene expression throughout all stages of plant development. Fruit ripening involves a complex scenario where drastic phenotypical and metabolic changes take place. Pepper fruits are
Salvador González-Gordo +5 more
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Potassium (K+) is an essential macro-element for plant growth and development given its implication in major processes such as photosynthesis, osmoregulation, protein synthesis, and enzyme function.
Hayet Houmani +5 more
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The class III peroxidases (PODs) catalyze the oxidation of several substrates coupled to the reduction of H2O2 to water, and play important roles in diverse plant processes.
Salvador González-Gordo +3 more
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