Results 81 to 90 of about 637,533 (361)

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Acute Effects of Photobiomodulation Therapy Combined with Static Magnetic Field in C2C12 Muscle Cells Exposed and Not Exposed to H₂O₂

Applied Sciences
Photobiomodulation (PBM) has been applied in biomedical technology to improve cellular responses. Specifically in sports medicine, it is used to accelerate metabolic and structural repair and adaptation in skeletal muscle under stress overload. Currently,
Marcos Vinicius Ferlito, João Vitor Ferlito, Fernando Joel Scariot, Mirian Salvador, Ernesto Cesar Pinto Leal-Junior, Thiago De Marchi, Catia Santos Branco   +6 more
doaj   +1 more source

Impact of Nitric Oxide (NO) on the ROS Metabolism of Peroxisomes

Plants, 2019
Nitric oxide (NO) is a gaseous free radical endogenously generated in plant cells. Peroxisomes are cell organelles characterized by an active metabolism of reactive oxygen species (ROS) and are also one of the main cellular sites of NO production in ...
Francisco J. Corpas, Luis A. del Río, José M. Palma   +2 more
doaj   +1 more source

Cellular Responses of Antioxidants Related to Degenerative Eye Disease Research

Oxidative stress is critical in degenerative retinal diseases. Antioxidants are considered to be potential therapeutics that can treat retinal diseases. Loss of retinal epithelium (RPE) is an important contributor to the degeneration of the retina.

core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Dietary antioxidants in coffee leaves: impact of botanical origin and maturity on chlorogenic acids and xanthones

, 2019
Natural polyphenols are important dietary antioxidants that significantly benefit human health. Coffee and tea have been shown to largely contribute to the dietary intake of these antioxidants in several populations.
Resmini, Marina, Colomban, Silvia, Silvia Colomban, Ângelo Monteiro, Luciano Navarini, Azinheira, Helena, Maria Do Céu Silva, Monteiro, Ângelo, Helena G. Azinheira, Marina Resmini, Navarini, Luciano, Silva, Maria do Céu, Leonor Guerra-Guimarães, Guerra-Guimarães, Leonor   +13 more
core   +1 more source

The impact of antioxidants on vitiligo and melasma : a scoping review and meta-analysis

, 2023
Reactive oxygen species (ROS) generated during melanogenesis make melanocytes particularly vulnerable to oxidative stress, influencing their survival and melanin synthesis. Oxidative stress, significantly present in vitiligo and recently also detected in
Nanja van Geel, van Geel, Nanja, Bulat, Vedrana, Vedrana Bulat, Marijn M. Speeckaert, Speeckaert, Reinhart, Reinhart Speeckaert, Speeckaert, Marijn   +7 more
core   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Early Origins of Hypertension: Should Prevention Start Before Birth Using Natural Antioxidants?

, 2020
Hypertension may originate in early life. Reactive oxygen species (ROS) generated due to the exposure of adverse in utero conditions causes developmental programming of hypertension.
Chien-Ning Hsu, You-Lin Tain
core   +1 more source