Results 101 to 110 of about 132,199 (306)

Final 2‐Year Results of the REFORM Study: A Randomized Trial of Biolimus DCB Versus Paclitaxel DCB for In‐Stent Restenosis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In the REFORM trial, treatment of coronary in‐stent restenosis with a Biolimus A9™ drug‐coated balloon (BCB) was found to be inferior with respect to in‐segment percentage stenosis at 6‐months in comparison to treatment with a standard paclitaxel coated paclitaxel‐coated balloon (PCB). Aims In this manuscript, the final prespecified
Daniel O'Callaghan, J. J. Coughlan, Fernando Alfonso, Joo‐Yong Hahn, Manel Sabate, Ralph Toelg, Samuel Copt, Sean Fitzgerald, Marie‐Claude Morice, Jasper Trevelyan, Darren Mylotte, Antonio Fernandez Ortiz, Rory Durand, Jochen Wöhrle, Franz Xever Kleber, Giuilo Stefanini, Himanshu Rai, Peter O'Kane, Robert A. Byrne   +18 more
wiley   +1 more source

Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity

, 2019
Oligonucleotides with an antiproliferative activity for human cancer cells have attracted attention over the past decades; many of them have a G-quadruplex structure (GQ), and a cryptic target.
Alexey Kopylov, Alexander Revishchin, Ekaterina Savchenko, Elena Zavyalova, Nadezhda Samoylenkova, Olga Antipova, Galina Pavlova   +6 more
core   +1 more source

Lysosome‐Targeted Squaramide Anion Transporters

Chemistry – A European Journal, EarlyView.
Lysosome‐targeted squaramide anion transporters elicit different biological effects depending on the targeting group employed. ABSTRACT Targeting anion transporters to specific organelles has previously been shown to be an effective strategy to enhance their cytotoxicities against cancerous cell lines.
Elba Feo, Edward York, Anthony Thai, William G. Ryder, Daniel A. McNaughton, Philip A. Gale   +5 more
wiley   +1 more source

The Antiproliferative Properties of Uncaria tomentosa Willd. DC. extracts against Caco2 and HeLa Cancer Cell Lines

, 2018
Introduction: Uncaria tomentosa is used in Central and South American folk medicine to treat a variety of diseases. It is particularly well known for treating cancer and studies have confirmed its activity against some carcinoma cell lines.
Cock, Ian Edwin, Joseph Shalom, Ian Edwin Cock, Shen, Jaixi, Jaixi Shen, Shalom, Joseph   +5 more
core   +1 more source

A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin

Chemistry – A European Journal, EarlyView.
The first high‐resolution structure of an OGRE‐derived G‐quadruplex from the chicken β‐globin replication origin reveals an intramolecular three‐layer (3+1) hybrid fold with a cytosine bulge and an unprecedented 5'‐outer‐quartet anti guanine, creating a distinctive surface for molecular recognition.
Yingying You, Monica Ching Suen, Haitao Miao, Yanyan Geng, Rahman Ud Din, Mu Yuan, Qiang Xue, Xiaoting Li, Naining Xu, Zhihong Guo, Hon‐Ming Lam, Kwok‐Wai Lo, Changdong Liu, Guang Zhu   +13 more
wiley   +1 more source

Antiproliferative, apoptotic induction, and antiinvasive effects of Leersia hexandra (L.) Sw., Panicum repens Linn., and Brachiaria mutica (Forsk.) Stapf extracts on human cancer cells [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2009
In vitro study of antiproliferation and cytotoxicity of the hexane and butanolic extracts of the three grass species, namely Leersia hexandra (L.) Sw. (“Yaa sai”), Panicum repens Linn. (“Yaa channakaat”), and Brachiaria mutica (Forsk.) Stapf (“Yaa khon”)
Kornkanok Ingkaninan, Chatri Ngamkitidechakul, Watcharin Panunto, Pintusorn Hansakul   +3 more
doaj  

Antiproliferative activity of Vietnamese medicinal plants

, 2002
Methanol, methanol\u2013water (1 : 1) and water extracts were prepared from seventy-seven Vietnamese medicinal plants and tested for their antiproliferative activities against human HT-1080 fibrosarcoma cells. Among them, fifteen extracts including seven
Tezuka, Yasuhiro, Banskota, Arjun Hari, Tran, Quan Le, Ueda, Jun-ya, Tran, Qui Kim, Saiki, Ikuo, Harimaya, Yuko, Kadota, Shigetoshi   +7 more
core   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Revealing the Phenolic Composition and the Antioxidant, Antimicrobial and Antiproliferative Activities of Two Euphrasia sp. Extracts

Plants
The species of the genus Euphrasia present important medicinal potential according to their traditional uses. However, few studies aim to sustain this fact by scientific evidence.
Daniela Benedec, Ilioara Oniga, Daniela Hanganu, Ana-Maria Vlase, Irina Ielciu, Gianina Crișan, Nicodim Fiţ, Mihaela Niculae, Timea Bab, Emoke Pall, Laurian Vlase   +10 more
doaj   +1 more source

Synthesis, antimicrobial, and antiproliferative activities of substituted phenylfuranylnicotinamidines

, 2016
Magdy M Youssef,1,2 Reem K Arafa,3,4 Mohamed A Ismail1,21Department of Chemistry, College of Science, King Faisal University, Hofuf, Saudi Arabia; 2Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, 3Department of Pharmaceutical ...
Ismail MA,, Youssef MM, Arafa RK
core