Results 111 to 120 of about 155,512 (310)
Marine Drugs, 2016 Cytoglobosins H (1) and I (2), together with seven known cytochalasan alkaloids (3–9), were isolated from the deep-sea-derived fungus Chaetomium globosum.
Zhihan Zhang +10 more
doaj +1 more source
Enzyme prodrug therapy achieves site-specific, personalized physiological responses to the locally produced nitric oxide [PDF]
, 2018 Nitric oxide (NO) is a highly potent but short-lived endogenous radical with a wide spectrum of physiological activities. In this work, we developed an enzymatic approach to the site-specific synthesis of NO mediated by biocatalytic surface coatings ...
Alexander N. Zelikin +12 more
core +2 more sources
BMEMat, EarlyView.A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen +9 more
wiley +1 more source
Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones
Molecules, 2016 The synthesis and antiproliferative activity of new benzimidazole derivatives bearing an hydrazone mojety at the 2-position is described. The new N′-(4-arylidene)-1H-benzo[d]imidazole-2-carbohydrazides were evaluated for their cytostatic activity toward ...
Valentina Onnis +8 more
doaj +1 more source
Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy
BMEMat, EarlyView.This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang +5 more
wiley +1 more source
Phytochemical study of the Genus Salpichroa (Solanaceae), chemotaxonomic considerations, and biological evaluation in prostate and breast cancer cells [PDF]
, 2017 Twelve Salpichroa taxa have been phytochemically analyzed. From the aerial parts of S. scandens, four known salpichrolides A, C, I, S, and an unreported withanolide named salpichrolide V (1), were isolated. In S. dependens, S. gayi, S.
Barboza, Gloria Estela +6 more
core +1 more source
Chemistry – A European Journal, EarlyView.This study reports six new copper(I) complexes with unusual coordination and strong anticancer activity against a panel of human cancer cell lines derived from different solid tumors. The most active compounds outperform cisplatin, even in resistant cells, by inhibiting protein disulfide isomerase and inducing redox stress that triggers non‐apoptotic ...
Vo Quang Huy Phan +9 more
wiley +1 more source
Annals of Agricultural and Environmental Medicine, 2019 Introduction and objective Since antiquity, C. babylonica (L.) L. extracts has been used as a remedy for primary health care in traditional medicine.
Nur Ceyhan Güvensen +4 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 A series of naphthalene-chalcone derivatives (3a–3t) were prepared and evaluated as tubulin polymerisation inhibitor for the treatment of breast cancer. All compounds were evaluated for their antiproliferative activity against MCF-7 cell line.
Guangcheng Wang +5 more
doaj +1 more source
Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro [PDF]
, 2003 The growth rate of numerous cancer cell lines is regulated in part by actions of neuropeptides of the vasoactive intestinal peptide (VIP) family, which also includes pituitary adenylate cyclase-activating peptide (PACAP), glucagon, and peptide histidine ...
Alleaume, Céline +4 more
core +1 more source