Results 111 to 120 of about 98,967 (297)

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Antiproliferative effect of benzophenones and their influence on cathepsin activity [PDF]

, 2015
CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFINEP – FINANCIADORA DE ESTUDOS E PROJETOSThe antiproliferative activity of two prenylated benzophenones isolated from Rheedia brasiliensis, the triprenylated garciniaphenone and the ...
Kohn, Luciana K., Nagem, Tanus Jorge, dos Santos, Marcelo Henrique, Murata, Ramiro Mendonça, Yatsuda, Regiane, de Carvalho, João Ernesto, Rosalen, Pedro Luiz, Martins, Felipe Terra, Alencar, Severino Matias   +8 more
core   +1 more source

Analysis and Biological Evaluation of Arisaema Amuremse Maxim Essential Oil

Open Chemistry, 2019
The chemical composition and antitumor activity of essential oil were compared for four parts of the Arisaema Amuremse Maxim. Chemical constituent of essential oil in every parts of Arisaema Amuremse Maxim was identified by GC-MS analysis systematically.
Li Guiying, Jiang Yueyao, Li Yingjun, He Tong, Wang Ying, Ji Tianyi, Zhai Wanchen, Zhao Lichun, Zhou Xiaoping   +8 more
doaj   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Synthetic cannabinoid quinones: Preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity [PDF]

, 2013
Chromenopyrazolediones have been designed and synthesized as anticancer agents using the multi-biological target concept that involves quinone cytotoxicity and cannabinoid antitumor properties.
Gómez-Cañas, María, Díaz-Laviada, Inés, Díaz-Laviada Marturet, Inés, Zúñiga, María C., Jagerovic, Nadine, Zúñiga, María, Gómez Cañas, María, Fernández Ruiz, José Javier, Morales, Paula, Vara, Diana, Goya, Pilar, Olea-Azar, Claudio, Fernández-Ruiz, Javier   +12 more
core   +1 more source

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

Advanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo, Zhenyuan Qian, Lei Wang, Weilang Xu, Yuxin Weng, Kai Jiang, Zaiyuan Ye, Ji Xu, Guangyuan Song   +8 more
wiley   +1 more source

Antimicrobial property and antiproliferative activity of Centaurea babylonica (L.) L. on human carcinomas and cervical cancer cell lines

Annals of Agricultural and Environmental Medicine, 2019
Introduction and objective Since antiquity, C. babylonica (L.) L. extracts has been used as a remedy for primary health care in traditional medicine.
Nur Ceyhan Güvensen, Dilek Keskin, Hatice Güneş, Müjgan Kesik Oktay, Hasan Yıldırım   +4 more
doaj   +1 more source

Synthesis and Antiproliferative Activity of Pyridinylcarbonylpyrimidines Against Melanoma Cell Line [PDF]

, 2011
The synthesis of the series of pyrimidinylamines 1a-d and pyrimidinylureas 1e-u bearing a novel pyridinylcarbonylpyrimidine scaffold and their antiproliferative activities against A375 human melanoma cell line were described.
���������
core   +1 more source

Helleborus purpurascens—Amino Acid and Peptide Analysis Linked to the Chemical and Antiproliferative Properties of the Extracted Compounds

Molecules, 2015
There is a strong drive worldwide to discover and exploit the therapeutic potential of a large variety of plants. In this work, an alcoholic extract of Helleborus purpurascens (family Ranunculaceae) was investigated for the identification of amino acids ...
Adina-Elena Segneanu, Ioan Grozescu, Florentina Cziple, Daniel Berki, Daniel Damian, Cristina Mariana Niculite, Alexandru Florea, Mircea Leabu   +7 more
doaj   +1 more source

Chemical Characterization and Antiproliferative Evaluation of Compounds Isolated from White Shrimp (Penaeus vannamei) By-Products

Biophysica
Cancer is the second leading cause of death worldwide, requiring more effective treatments. By-products from the white shrimp (Penaeus vannamei) are a promising source of bioactive compounds.
Héctor Enrique Trujillo-Ruiz, Dania Guadalupe Leal-Rodríguez, Hisila del Carmen Santacruz-Ortega, Oliviert Martínez-Cruz, Sandra Carolina De La Reé-Rodríguez, Armando Burgos-Hernández, Erika Silva-Campa, Ángel Antonio Carbonell-Barrachina, Carmen María López-Saiz   +8 more
doaj   +1 more source