Results 121 to 130 of about 98,614 (298)
Investigating the Antiproliferative Activity of Synthetic Troponoids
, 2016 Troponoid (more commonly, tropone/tropolone) refers to a family of naturally occurring compounds with a unique seven-membered aromatic ring. As with many secondary metabolites, many of the tropolones display a wide range of biological activity.
Falcone, Eric R
core
Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy
BMEMat, EarlyView.This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang +5 more
wiley +1 more source
Molecules, 2015 There is a strong drive worldwide to discover and exploit the therapeutic potential of a large variety of plants. In this work, an alcoholic extract of Helleborus purpurascens (family Ranunculaceae) was investigated for the identification of amino acids ...
Adina-Elena Segneanu +7 more
doaj +1 more source
The Structure–Antiproliferative Activity Relationship of Pyridine Derivatives
Pyridine, a compound with a heterocyclic structure, is a key player in medicinal chemistry and drug design. It is widely used as a framework for the design of biologically active molecules and is the second most common heterocycle in FDA-approved drugs ...
Mayra Lizett González-Félix +8 more
core +1 more source
Antiproliferative activity of terpene-phospholipids against human cancer cell lines.
, 2017 Antiproliferative activity of terpene-phospholipids against human cancer cell lines.
Anna Gliszczyńska (2839163) +4 more
core +1 more source
Lysosome‐Targeted Squaramide Anion Transporters
Chemistry – A European Journal, EarlyView.Lysosome‐targeted squaramide anion transporters elicit different biological effects depending on the targeting group employed. ABSTRACT Targeting anion transporters to specific organelles has previously been shown to be an effective strategy to enhance their cytotoxicities against cancerous cell lines.
Elba Feo +5 more
wiley +1 more source
BiophysicaCancer is the second leading cause of death worldwide, requiring more effective treatments. By-products from the white shrimp (Penaeus vannamei) are a promising source of bioactive compounds.
Héctor Enrique Trujillo-Ruiz +8 more
doaj +1 more source
Antioxidative and antiproliferative activity of polygonum minus leaves extracts [PDF]
, 2015 Cancer is one of the leading causes of death in the world, particularly in developing countries. Cancer prevention by dietary constituents has emerged as a novel approach to reduce the number of cancer incidence.
Arumugam, Gayathiri
core
Epilepsia Open, EarlyView.Abstract Objective High‐grade astrocytomas, including glioblastomas, are aggressive brain tumors with poor prognosis and a 5‐year survival below 7%. Seizures affect up to 75% of glioma patients, especially in low‐grade tumors but also in high‐grade cases.
Matteo Impellizzeri +7 more
wiley +1 more source
Design and synthesis of novel oridonin analogues as potent anticancer agents
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 To identify anticancer agents with higher potency and lower toxicity, a series of oridonin derivatives with substituted benzene moieties at the C17 position were designed, synthesised, and evaluated for their antiproliferative properties.
Qing-Kun Shen +6 more
doaj +1 more source