Results 201 to 210 of about 24,129 (266)

Isolation and characterization of antiprotozoal compound-producing Streptomyces species from Mongolian soils.

Parasitology international, 2020
Natural resources are recognized as important sources of potential drugs for treating various infections, and microorganisms are a rich natural source of diverse compounds.
Baldorj Pagmadulam, D. Tserendulam, Tserennadmid Rentsenkhand, M. Igarashi, R. Sawa, Coh-ichi Nihei, Y. Nishikawa   +6 more
semanticscholar   +1 more source

Novel Cocrystals and Eutectics of the Antiprotozoal Tinidazole: Mechanochemical Synthesis, Cocrystallization, and Characterization

, 2020
Antiprotozoal tinidazole (TNZ) exhibits low aqueous solubility (Sw) and poor photochemical stability.
O. Fandiño, Lucía Reviglio, Y. G. Linck, G. Monti, M. M. Marcos Valdez, S. Faudone, M. Caira, N. Sperandeo   +7 more
semanticscholar   +1 more source

Antiprotozoal activity of ferroquine

Parasitology Research, 2012
Ferroquine (FQ, SSR97193) is a synthetic compound currently in development for the treatment of malaria. The use of a single compound to treat several parasitoses would be very convenient for multi-infected patients and also for financial considerations.
Pomel, S., Biot, Christophe, Bories, C, Loiseau, P.M.   +3 more
openaire   +2 more sources

Recent Advances in the Development of Broad-Spectrum Antiprotozoal Agents.

Current Medicinal Chemistry, 2020
Infections caused by Trypanosoma brucei, Trypanosoma cruzi, Leishmania spp., Entamoeba histolytica, Giardia lamblia, Plasmodium spp., and Trichomonas vaginalis, are part of a large list of human parasitic diseases.
A. Moreno-Herrera, Sandra Cortez-Maya, V. Bocanegra-García, B. Banik, G. Rivera   +4 more
semanticscholar   +1 more source

Antiprotozoal Resistance

Antiprotozoal drug resistance is a major challenge in the treatment and control of protozoal infections. Protozoan parasites (members of the phylum Protozoa), which are among the major livestock pathogens, e.g., Theileria, Babesia and Trypanosoma, have developed various mechanisms to evade the effects of antiprotozoal drugs, including reduced drug ...
Abbas, Haider, Younus, Muhammad, Fareed, Zahid, Saleem, Mian Mubashar, Jones, Malcolm K., Raheemi, Hazrat Ullah, Ijaz, Adil, Saleem, Muhammad Nadeem   +7 more
openaire   +2 more sources

Antiprotozoal activity in citrinin

Bulletin of Environmental Contamination and Toxicology, 1976
Citrinin has an inhibitory effect on growth of T. pyriformis. Citrinin also caused a shift to smaller cell size, particularly at the higher concentrations (25, 50 and 100 mug/ml). The mycotoxin exerted only a marginal effect on the respiration of T. pyriformis; but citrinin (25 mug/ml) induced an inhibitory effect on DNA, RNA and protein content.
A W, Hayes, H E, Birkhead, E A, Hall
openaire   +2 more sources

Structure and Absolute Configuration of Abietane Diterpenoids from Salvia clinopodioides: Antioxidant, Antiprotozoal, and Antipropulsive Activities.

Journal of Natural Products, 2019
The aerial parts of Salvia clinopodioides afforded abietanes 1a, 2a, and 3 (clinopodiolides A-C), two of which possess an unusual lactol moiety at C-19-C-20, together with an icetexane named clinopodiolide D (4a).
Celia Bustos-Brito, P. Joseph-Nathan, E. Burgueño-Tapia, D. Martínez-Otero, A. Nieto-Camacho, F. Calzada, L. Yépez-Mulia, B. Esquivel, L. Quijano   +8 more
semanticscholar   +1 more source

Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.

Journal of Medicinal Chemistry, 2019
We have designed and synthesized a series of new imidazole-based compounds structurally related to an antiprotozoal agent with nanomolar activity which we identified recently.
Francesco Saccoliti, V. N. Madia, Valeria Tudino, A. De Leo, L. Pescatori, A. Messore, D. De Vita, L. Scipione, R. Brun, M. Kaiser, P. Mäser, C. M. Calvet, Gareth K. Jennings, L. Podust, G. Pepe, R. Cirilli, C. Faggi, A. Di Marco, Maria Rosaria Battista, V. Summa, R. Costi, R. Di Santo   +21 more
semanticscholar   +1 more source

Synthesis and systemic toxicity assessment of quinine-triazole scaffold with antiprotozoal potency.

Bioorganic chemistry (Print), 2019
A series of hybrid antiprotozoal compounds with quinine-triazolyl scaffold were prepared by copper catalyzed Huisgen 1,3-dipolar cycloaddition via O-mesylation with mesyl chloride followed by azide displacement.
Adarsh Sahu, R. Agrawal, Rajkishor Pandey   +2 more
semanticscholar   +1 more source

Antiprotozoal

2021
Adrienne T. Black, Sidhartha D. Ray
openaire   +1 more source