Results 181 to 190 of about 17,418 (254)

Seasonal and Organ-Specific Variations of Alkaloids in <i>Buxus obtusifolia</i> (Mildbr.) Hutch: A Multivariate LC/MS Study. [PDF]

Plants (Basel)
Mukavi JW, Sendker J, Kimani NM, Omosa LK, Schmidt TJ.   +4 more
europepmc   +1 more source

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Thiazolidin-4-one-based derivatives – Efficient tools for designing antiprotozoal agents. A review of the last decade

Bioorganic Chemistry, 2023
Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical significance for medicinal chemistry. This heterocyclic ring has been reported to possess a variety of biological activities, including antiprotozoal activities ...
Nazar Trotsko, Sławomir Mańdziuk, Jacek Szczepański   +2 more
exaly   +2 more sources

Prospects of halofuginone as an antiprotozoal drug scaffold.

Drug Discovery Today, 2022
Halofuginone is a clinically active derivative of febrifugine, first isolated from the Chinese herb Dichroa febrifuga. The beneficial biological effects of halofuginone on various diseases, including parasitic diseases, cancer, fibrosis, and autoimmune ...
J. Gill, Amit Sharma
semanticscholar   +1 more source

Synthesis of chalcone derivatives by Claisen-Schmidt condensation and in vitro analyses of their antiprotozoal activities

Natural Product Research, 2022
Chalcone is a molecule with known biological activities. Based on this, a series of chalcone derivatives bearing methyl, phenyl or furanyl substituents at different positions of A and B rings were synthesised, characterised, and evaluated regarding ...
Gabriella B Souza, T.M.C. Santos, A. S. Silva, A. Barreiros, V. Nardelli, I. Siqueira, S. Dolabella, Emmanoel V. Costa, P. Alves, R. Scher, R. P. Fernandes   +10 more
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Antimicrobial peptides: On future antiprotozoal and anthelminthic applications.

Acta Tropica, 2022
Control and elimination of parasitic diseases are nowadays further complicated by emergence of drug resistance. Drug resistance is a serious threat as there are not many effective antiparasitic drugs available.
Kathyleen S Nogrado, Poom Adisakwattana, Onrapak Reamtong   +2 more
semanticscholar   +1 more source

Spectroscopic elucidation (FT-IR, FT-Raman and UV-visible) with NBO, NLO, ELF, LOL, drug likeness and molecular docking analysis on 1-(2-ethylsulfonylethyl)-2-methyl-5-nitro-imidazole: An antiprotozoal agent

Comput. Biol. Chem., 2020
1-(2-ethylsulfonylethyl)-2-methyl-5-nitro-imidazole (1EMI) C8H13N3O4S also known as Tinidazole, selected for its antiprotozoal property is extensively used for spectroscopic elucidations and computational aspects using density functional methods.
P. Manjusha, J. Prasana, S. Muthu, B. Fathima Rizwana   +3 more
semanticscholar   +1 more source

Recent Advances in the Medicinal Chemistry of Phenothiazines. New Anticancer and Antiprotozoal Agents.

Current Medicinal Chemistry, 2021
BACKGROUND Molecules that have a phenothiazine scaffold have been considered versatile organic structures with a wide variety of biological activities: antipsychotic, anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antimalarial, and ...
Alonzo González-González, Lenci K. Vázquez-Jiménez, Alma D. Paz-González, M. Bolognesi, Gildardo Rivera   +4 more
semanticscholar   +1 more source

Antiprotozoal agents: How have they changed over a decade?

Archiv der Pharmazie, 2021
Neglected tropical diseases are a diverse group of communicable diseases that are endemic in low‐ or low‐to‐middle‐income countries located in tropical and subtropical zones.
Vitória de Souza Fernandes, Rafael da Rosa, L. Zimmermann, Kamilla R Rogério, A. Kümmerle, L. S. C. Bernardes, Cedric S. Graebin   +6 more
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Antiprotozoal activity in citrinin

Bulletin of Environmental Contamination and Toxicology, 1976
Citrinin has an inhibitory effect on growth of T. pyriformis. Citrinin also caused a shift to smaller cell size, particularly at the higher concentrations (25, 50 and 100 mug/ml). The mycotoxin exerted only a marginal effect on the respiration of T. pyriformis; but citrinin (25 mug/ml) induced an inhibitory effect on DNA, RNA and protein content.
A W, Hayes, H E, Birkhead, E A, Hall
openaire   +2 more sources

Antiprotozoal activity of ferroquine

Parasitology Research, 2012
Ferroquine (FQ, SSR97193) is a synthetic compound currently in development for the treatment of malaria. The use of a single compound to treat several parasitoses would be very convenient for multi-infected patients and also for financial considerations.
Pomel, S., Biot, Christophe, Bories, C, Loiseau, P.M.   +3 more
openaire   +3 more sources