Results 191 to 200 of about 24,129 (266)

Crystallographic and computational characterization and in silico target fishing of six aromatic and aliphatic sulfonamide derivatives. [PDF]

open access: yesR Soc Open Sci
Nguyen AV   +9 more
europepmc   +1 more source

Thiazolidin-4-one-based derivatives – Efficient tools for designing antiprotozoal agents. A review of the last decade

Bioorganic Chemistry, 2023
Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical significance for medicinal chemistry. This heterocyclic ring has been reported to possess a variety of biological activities, including antiprotozoal activities ...
Helena Tuszewska   +2 more
exaly   +2 more sources

Prospects of halofuginone as an antiprotozoal drug scaffold.

Drug Discovery Today, 2022
Halofuginone is a clinically active derivative of febrifugine, first isolated from the Chinese herb Dichroa febrifuga. The beneficial biological effects of halofuginone on various diseases, including parasitic diseases, cancer, fibrosis, and autoimmune ...
J. Gill, Amit Sharma
semanticscholar   +1 more source

Antimicrobial peptides: On future antiprotozoal and anthelminthic applications.

Acta Tropica, 2022
Control and elimination of parasitic diseases are nowadays further complicated by emergence of drug resistance. Drug resistance is a serious threat as there are not many effective antiparasitic drugs available.
Kathyleen S Nogrado   +2 more
semanticscholar   +1 more source

Spectroscopic elucidation (FT-IR, FT-Raman and UV-visible) with NBO, NLO, ELF, LOL, drug likeness and molecular docking analysis on 1-(2-ethylsulfonylethyl)-2-methyl-5-nitro-imidazole: An antiprotozoal agent

Comput. Biol. Chem., 2020
1-(2-ethylsulfonylethyl)-2-methyl-5-nitro-imidazole (1EMI) C8H13N3O4S also known as Tinidazole, selected for its antiprotozoal property is extensively used for spectroscopic elucidations and computational aspects using density functional methods.
P. Manjusha   +3 more
semanticscholar   +1 more source

Recent Advances in the Medicinal Chemistry of Phenothiazines. New Anticancer and Antiprotozoal Agents.

Current Medicinal Chemistry, 2021
BACKGROUND Molecules that have a phenothiazine scaffold have been considered versatile organic structures with a wide variety of biological activities: antipsychotic, anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antimalarial, and ...
Alonzo González-González   +4 more
semanticscholar   +1 more source

Antiprotozoal agents: How have they changed over a decade?

Archiv der Pharmazie, 2021
Neglected tropical diseases are a diverse group of communicable diseases that are endemic in low‐ or low‐to‐middle‐income countries located in tropical and subtropical zones.
Vitória de Souza Fernandes   +6 more
semanticscholar   +1 more source

N-Mannich bases of benzimidazole as a potent antitubercular and antiprotozoal agents: Their synthesis and computational studies

Synthetic Communications, 2020
This article dealing with the microwave assisted synthesis of N-Mannich bases of pyridine clubbed with two different benzimidazole cores with their micromolar biological potency.
V. M. Patel   +3 more
semanticscholar   +1 more source

Antiprotozoal and anthelmintic activity of zinc oxide nanoparticles.

Current Medicinal Chemistry, 2021
Nanomaterials represent a wide alternative for the treatment of several diseases that affect both human and animal health. The use of these materials mainly involves trying to solve the problem of resistance that pathogenic organisms acquire to ...
J. R. do Carmo Neto   +4 more
semanticscholar   +1 more source

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