Results 51 to 60 of about 7,779 (200)
The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus
Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Olha Mykhailenko +3 more
wiley +1 more source
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 1, January 2026.ABSTRACT Aim To estimate the prevalence of medication use in nonhospitalized pregnant women with COVID‐19. Methods A prospective two‐stage individual patient meta‐analysis across 10 data sources in Europe and North America studied medication use among nonhospitalized pregnant women with COVID‐19 between January 2020 and December 2022.
Odette de Bruin +72 more
wiley +1 more source
Analogs of 5-methylthioribose, a novel class of antiprotozoal agents [PDF]
Antimicrobial Agents and Chemotherapy, 1988 Since drug resistance and toxicity limit the use of available antiprotozoal agents, it is important that new drugs be developed as soon as possible. In this study, the method by which several protozoa degrade 5'-methylthioadenosine (MTA) was shown to differ from MTA catabolism in human cells.
M K, Riscoe, A J, Ferro, J H, Fitchen
openaire +2 more sources
Advances in Agriculture, Volume 2026, Issue 1, 2026.Coccidiosis is one of the most common diseases in the poultry industry worldwide (especially in broilers aged 3–6 weeks), causing significant economic losses to poultry farmers and governments every year. Conventional methods (anticoccidial chemical compounds) for the coccidiosis debarment and control always present challenges and disadvantages, such ...
Fatemeh Aziz-Aliabadi +3 more
wiley +1 more source
Acyclic Nucleoside Phosphonates As Potential Inhibitors of Plasmodium Falciparum Egress
Chemistry – A European Journal, Volume 31, Issue 69, December 9, 2025.Exploration of the chemistry of acyclic nucleoside phosphonates allowed us to study structural diversity from the hit compound; biological evaluation and molecular docking were performed to decipher key interactions with the putative target. Abstract The emergence of drug‐resistant Plasmodium strains requires the development of novel antimalarial ...
Thomas Cheviet +6 more
wiley +1 more source
Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents
Bioorganic & Medicinal Chemistry Letters, 2006 Compounds 10a (IC50 110 pM) and 21 (IC50 40 pM) are the most potent inhibitors of Eimeria tenella cGMP-dependent protein kinase activity reported to date and are efficacious in the in vivo antiparasitic assay when administered to chickens at 12.5 and 6.25 ppm levels in the feed.
Tesfaye Biftu +21 more
openalex +3 more sources
SIP‐SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B
Advanced Science, Volume 12, Issue 48, December 29, 2025.We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Meng Zhang +6 more
wiley +1 more source
Synthesis of Possible Antiprotozoal Agents
, 1984 Department of Chemical Technology, University College of Science, 92, Acharya P. C. Road, Calcutta-700 009 Manuscript received 3 December 1982, revised 30 November 1983, accepted 26 May 1984 Synthesis of Possible Antiprotozoal ...
B. R. SARKAR, D. GHOSH, B. C. PATHAK
openaire +1 more source
Chemical Composition, Antioxidant, and Antibacterial Activities of Mezilaurus duckei (Lauraceae)
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT Mezilaurus duckei, a Brazilian endemic tree species found exclusively in the Amazon Rainforest, is primarily exploited for timber in construction. Due to its endangered status, this study aimed to investigate the chemical profile and biological properties of the ethanolic extract and its phases derived from M. duckei leaves. Chemical profiling
Bruna S. Moroto +7 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Synthesis of 8‐hydroxyquinoline derivatives (QD 1‐12) from different analogues of 8‐hydroxyquinoline (HQ 1‐4). The derivatives and parent compounds were evaluated for antibacterial and antibiofilm activity against Mycobacterium tuberculosis, Mycobacterium smegmatis, methicillin‐resistant Staphylococcus aureus and methicillin‐sensitive Staphylococcus ...
Namrita Lall +9 more
wiley +1 more source