Results 51 to 60 of about 6,609 (178)

Structures, targets and recent approaches in anti-leishmanial drug discovery and development. [PDF]

open access: yes, 2011
Recent years have seen a significant improvement in available treatment options for leishmaniasis. Two new drugs, miltefosine and paromomycin, have been registered for the treatment of visceral leishmaniasis (VL) in India since 2002.
Seifert, Karin
core   +2 more sources

Exploring Synthetic Dihydrobenzofuran and Benzofuran Neolignans as Antiprotozoal Agents against Trypanosoma cruzi

open access: yesPharmaceutics, 2023
Chagas disease is a neglected tropical disease that affects more than 8 million people. Although there are therapies against this disease, the search for new drugs is important because the current treatments show limited effectiveness and high toxicity ...
Mariana C. Pagotti   +10 more
doaj   +1 more source

Looking for Greener Pastures: In Vitro Screening of Phytogenics for the Control of Sparicotyle chrysophrii in Gilthead Sea Bream

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT The gill parasite Sparicotyle chrysophrii poses a significant threat to gilthead sea bream (Sparus aurata) aquaculture in the Mediterranean, causing considerable mortality and economic losses. As traditional chemotherapeutic treatments, like formalin, face growing regulatory restrictions, there is an urgent need for alternative control ...
Teresa Pirollo   +8 more
wiley   +1 more source

Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]

open access: yes, 2012
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis   +6 more
core   +3 more sources

Efficacy of 0.2% povidone‐iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 438-447, March 2025.
Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Anna Farkas   +4 more
wiley   +1 more source

Effects of temperature and humidity on the presence and prevalence of a common fungal parasite on an invasive ladybird

open access: yesEcological Entomology, Volume 51, Issue 1, Page 86-97, February 2026.
We investigated how temperature and relative humidity influence the parasitic fungus Hesperomyces harmoniae on the invasive ladybird Harmonia axyridis under controlled laboratory conditions. Abiotic factors significantly affect parasitism: High relative humidity increased parasite prevalence, development rate, and load, while both low and high ...
Michiel D. de Groot   +8 more
wiley   +1 more source

Antiprotozoal and antimycobacterial activities of Persea americana seeds [PDF]

open access: yes, 2013
BACKGROUND: Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.
Adelina Jiménez-Arellanes   +5 more
core   +1 more source

The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Olha Mykhailenko   +3 more
wiley   +1 more source

The Pharmacological Potential of Mushrooms [PDF]

open access: yes, 2005
This review describes pharmacologically active compounds from mushrooms. Compounds and complex substances with antimicrobial, antiviral, antitumor, antiallergic, immunomodulating, anti-inflammatory, antiatherogenic, hypoglycemic, hepatoprotective and ...
Jülich, Wolf-Dieter   +2 more
core   +3 more sources

Trypanocidal Effects of Polyprenylated Benzophenone Enriched Brazilian Red Propolis Extract and Its Isolated Constituent

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
In vitro trypanocidal activity of a polyprenylated benzophenone‐enriched Brazilian red propolis extract (SEBz) and its major constituents, guttiferone E/xanthochymol (GUT/XAN) and oblongifolin B (OBL), exhibit in vitro trypanocidal activity against Trypanosoma cruzi, inducing ultrastructural damage with moderate cytotoxicity and no significant ...
Nicoli Dias Oliveira   +9 more
wiley   +1 more source

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