Results 61 to 70 of about 7,779 (200)
eFood, Volume 6, Issue 6, December 2025.Essential oils (EOs) from peppermint, thyme, eucalyptus, and lemongrass were extracted and characterized by GC‐MS, then combined and nano‐formulated. All extracts showed antiviral activity, with the nano‐mixture exhibiting the strongest effect against influenza A and SARS‐CoV‐2.
Sobhy Mohamed Mohsen +7 more
wiley +1 more source
The Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1889-1899, December 2025.Abstract In Japan, the percentage of approved drugs with pediatric indications increased to 30% in 2010‐2015, but no further increase was observed through 2020. The Ministry of Health, Labor, and Welfare in Japan presented draft future directions to promote pediatric drug development, where the modeling and simulation (M&S) approach was introduced as a
Akinori Nakashima +5 more
wiley +1 more source
Pathogens, 2019 The incidence of neglected diseases in tropical countries, such as Leishmaniasis and Chagas’s disease, is attributed to a set of biological and ecological factors associated with the socioeconomic context of developing countries and with a ...
Eliana B. Souto +8 more
doaj +1 more source
Chemistry, Applications, and Synthesis Methods of Indole Derivatives: A Comprehensive Review
The Chemical Record, Volume 25, Issue 12, December 2025.Indole and its derivatives represent a vital class of heterocycles with broad applications in pharmaceuticals, agrochemicals, and materials science. This review explores their applications, biosynthesis, key derivatives such as tryptophan, and presents an overview of both classical and modern synthetic methodologies, with a focus on sustainable ...
Raphael Silva Moratório de Moraes +10 more
wiley +1 more source
Journal of Experimental Pharmacology, 2022 Leena Abdulaziz,1 Esraa Elhadi,1,2 Ejlal A Abdallah,3 Fadlalbaseer A Alnoor,4 Bashir A Yousef5 1Department of Pharmacology, Faculty of Pharmacy, Omdurman Islamic University, Khartoum, 14415, Sudan; 2Jiangsu Key Laboratory of Drug Screening, China ...
Abdulaziz L +4 more
doaj
Mining Actinomycetes' Metabolomes and Genomes for Anti‐Phytophthora infestans Compounds
Microbial Biotechnology, Volume 18, Issue 12, December 2025.Using a comparative metabolomic and genomic approach on 63 actinomycetes, this study identified 75 compounds associated with the strains' ability to inhibit the late blight‐causing agent Phytophthora infestans. This study highlighted the promise of applying multi‐omics techniques on closely related strains differing in biological activity to pinpoint ...
Ola Abdelrahman +6 more
wiley +1 more source
Understanding the rationale for metronidazole use in dogs and cats
Journal of Small Animal Practice, Volume 66, Issue 12, Page 909-917, December 2025.Objective It is currently unknown how often antibiotics (including metronidazole) are used for non‐antibacterial purposes in dogs and cats. This study looked to characterise the rationale for metronidazole prescription in these species. Methods Retrospective cohort study.
J. Ng +11 more
wiley +1 more source
Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis +9 more
wiley +1 more source
Structural modifications of quinoline-based antimalarial agents: Recent developments
Journal of Pharmacy and Bioallied Sciences, 2010 Antimalarial drugs constitute a major part of antiprotozoal drugs and have been in practice for a long time. Antimalarial agents generally belong to the class of quinoline which acts by interfering with heme metabolism. The recent increase in development
Sandhya Bawa +3 more
doaj +1 more source