Behaviour change interventions to influence antimicrobial prescribing: a cross-sectional analysis of reports from UK state-of-the-art scientific conferences [PDF]
, 2017 Background To improve the quality of antimicrobial stewardship (AMS) interventions the application of behavioural sciences supported by multidisciplinary collaboration has been recommended.
Charani, E +6 more
core +2 more sources
Quinolines: the role of substitution site in antileishmanial activity
Frontiers in ChemistryLeishmaniasis is one of the most widespread parasitic diseases in the world, primarily affecting the poorest and most vulnerable populations. The development of new therapeutic agents that are more efficient, safe, and selective remains a challenge.
Orlando G. Elso +1 more
doaj +1 more source
SIP‐SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B
Advanced Science, Volume 12, Issue 48, December 29, 2025.We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Meng Zhang +6 more
wiley +1 more source
Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells [PDF]
, 2013 BACKGROUND: Multidrug resistance (MDR) is a major hurdle for cancer treatment worldwide and accounts for chemotherapy failure in over 90% of patients with metastatic cancer.
Armelle T Mbaveng +6 more
core +1 more source
Chemical Composition, Antioxidant, and Antibacterial Activities of Mezilaurus duckei (Lauraceae)
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT Mezilaurus duckei, a Brazilian endemic tree species found exclusively in the Amazon Rainforest, is primarily exploited for timber in construction. Due to its endangered status, this study aimed to investigate the chemical profile and biological properties of the ethanolic extract and its phases derived from M. duckei leaves. Chemical profiling
Bruna S. Moroto +7 more
wiley +1 more source
Activity of 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines to Tetrahymena [PDF]
, 2012 A series 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines (43 compounds), some of which are epidermal growth 22 factor tyrosine kinase inhibitors, were tested for their protozoal toxicity using an environmental Tetrahy- 23 mena strain as model organism.
Charnock, Colin +3 more
core +4 more sources
Pathogens, 2019 The incidence of neglected diseases in tropical countries, such as Leishmaniasis and Chagas’s disease, is attributed to a set of biological and ecological factors associated with the socioeconomic context of developing countries and with a ...
Eliana B. Souto +8 more
doaj +1 more source
Flavonoids from Piper Species as Promising Antiprotozoal Agents against Giardia intestinalis: Structure-Activity Relationship and Drug-Likeness Studies [PDF]
, 2022 Juan C. Ticona +6 more
openalex +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Synthesis of 8‐hydroxyquinoline derivatives (QD 1‐12) from different analogues of 8‐hydroxyquinoline (HQ 1‐4). The derivatives and parent compounds were evaluated for antibacterial and antibiofilm activity against Mycobacterium tuberculosis, Mycobacterium smegmatis, methicillin‐resistant Staphylococcus aureus and methicillin‐sensitive Staphylococcus ...
Namrita Lall +9 more
wiley +1 more source
Triclosan-caffeic acid hybrids: Synthesis, leishmanicidal, trypanocidal and cytotoxic activities [PDF]
, 2017 The synthesis, cytotoxicity, anti-leishmanial and anti-trypanosomal activities of twelve triclosan-caffeic acid hybrids are described herein. The structure of the synthesized products was elucidated by a com- bination of spectrometric analyses.
Agut, Raúl +8 more
core +1 more source