Results 71 to 80 of about 7,779 (200)

Exploring Quinazoline Nitro-Derivatives as Potential Antichagasic Agents: Synthesis and In Vitro Evaluation

Molecules
Trypanosoma cruzi is a protozoan parasite that causes Chagas disease in humans. The current antichagasic drugs nifurtimox and benznidazole have inconveniences of toxicity; therefore, the search for alternative therapeutic strategies is necessary.
Citlali Vázquez, Audifás-Salvador Matus-Meza, Oswaldo Nuñez-Moreno, Brenda Michelle Barbosa-Sánchez, Victor Manuel Farías-Gutiérrez, Mariana Mendoza-Conde, Francisco Hernández-Luis, Emma Saavedra   +7 more
doaj   +1 more source

Solubility enhancement of antiprotozoal agent by solid dispersion and herbal tablet method to improve its rate of dissolution

, 2022
Sourabh Jain, Ms. Ragini Bundela, Karunakar Shukla, Limhan Sachin Sadu, Limhan Sachin Sadu   +4 more
openalex   +1 more source

Design, Synthesis, In Vitro and In Silico Biological Evaluation of New Pyridine-2,5-Dicarboxylates Esters Bearing Natural Source Fragments as Anti-Trypanosomatid Agents

Pharmaceutics
Background: Chagas disease and leishmaniasis remain public health concerns. Despite the existence of approved medications for the treatment of these diseases, most patients discontinue treatment due to long drug regimens and/or the severe side effects of
Luis M. Sánchez-Palestino, Adriana Moreno-Rodríguez, Diana V. Navarrete-Carriola, Marlet Martínez-Archundia, Marhian López-Vargas, Liliana Argueta-Figueroa, Lenci K. Vázquez-Jiménez, Alma D. Paz-González, Eyra Ortiz-Pérez, Michael P. Doyle, Gildardo Rivera   +10 more
doaj   +1 more source

48: DRUG SCREENING OF NOVEL ANTIPROTOZOAL AGENTS AGAINST GIARDIA DUODENALIS

Journal of Global Antimicrobial Resistance, 2022
B. Knight, R. Abraham, S.W. Page, S. Abraham   +3 more
doaj   +1 more source

Repositioning Imipramine for Antiparasitic Effects Against Giardia lamblia

Drugs and Drug Candidates
Background/Objectives: Giardia lamblia is an intestinal protozoan responsible for giardiasis, a globally prevalent parasitic disease. Current therapeutic options, including nitroimidazoles and benzimidazoles, have increasing treatment failures due to ...
Xareni Zinereth Herrera-Valero, Sendar Daniel Nery-Flores, Filiberto Gutiérrez-Gutiérrez, Lizeth Guadalupe Campos-Múzquiz, Sandra Cecilia Esparza-González, Raúl Rodríguez-Herrera, Lissethe Palomo-Ligas   +6 more
doaj   +1 more source

Surveillance of Drug Residue Profiles in Gallus gallus domesticus (Silkie Chickens) in Taiwan

Animals
Veterinary drugs are extensively utilized in poultry farming for purposes such as disease prevention, disease treatment, and feed efficiency enhancement. However, the application of these drugs can lead to unacceptable residues in edible products.
Chiao-Hsu Ke, Jr-Wei Chen, Chen-Si Lin
doaj   +1 more source

Chalcone derivatives as potential antifungal agents: Synthesis, and antifungal activity

Journal of Advanced Pharmaceutical Technology & Research, 2015
Much research has been carried out with the aim to discover the therapeutic values of chalcone derivatives. Chalcones possess wide range of pharmacological activity such as antibacterial, antimalarial, antiprotozoal, antitubercular, anticancer, and ...
Deepa Gupta, D K Jain
doaj   +1 more source

Sensitivity of L. casei and E. сoli to active substances of anti-parasitic preparations

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2018
The data of the influence of active substances of anthelmintic and antiprotozoal preparations on the growth of L. casei IMB B-7280 and E. coli 055K59 are provided in the article.
R.A. Peleno
doaj   +1 more source

Antiprotozoal agents from higher plants

, 1992
La malaria, les amibiases, leishmanioses et trypanosomiases sont des maladies tropicales importantes provoquées par des protozoaires. De nouveaux médicaments sont nécessaires pour soigner ces maladies, et il est essentiel d'évaluer l'efficacité et la toxicité des plantes utilisées en médecine traditionnelle pour le traitement de ces infections. Pour de
Phillipson, D.J., Wright, C.W.
openaire   +1 more source

Trypanocidal potentials of Jatropha curcas L. 1753 leaf extracts and fractions in vivo

Pharmacological Research - Modern Chinese Medicine
Introduction: Trypanosomiasis is a debilitating parasitic disease affecting both humans and animals, leading to substantial economic losses in the livestock sector due to reduced productivity and increased mortality.
Haolat Yusuf, Abdulhakeem Binhambali, Mutiu Olawale Rahmon, Ridwan Bolaji Yusuf, Suleiman Garba Salihu, Barnabas Jarumi Musa   +5 more
doaj   +1 more source