Results 41 to 50 of about 3,371,263 (384)

QT interval prolongation related to psychoactive drug treatment: a comparison of monotherapy versus polytherapy

open access: yesAnnals of General Psychiatry, 2005
Background Several antipsychotic agents are known to prolong the QT interval in a dose dependent manner. Corrected QT interval (QTc) exceeding a threshold value of 450 ms may be associated with an increased risk of life threatening arrhythmias ...
Piccinelli Marco   +9 more
doaj   +1 more source

Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes. [PDF]

open access: yes, 2017
IntroductionThere are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package insert does not recommend bridging with oral ...
Hsia, Stephanie L   +4 more
core   +2 more sources

Direct and Indirect Drug Design Approaches for the Development of Novel Tricyclic Antipsychotics: Potential 5-HT2A Antagonist

open access: yesJournal of Chemistry, 2013
Schizophrenia is a mental disorder manifested largely by disintegration of thought processes and emotional responsiveness. Given the therapeutic and toxic limitations of clinically available drugs, it is clear that there is still a need for the ...
Mahantesh Namdev Jadhav   +3 more
doaj   +1 more source

Assessment of adherence to treatment with injectable extended-release antipsychotics within a pharmacotherapeutic follow-up program [PDF]

open access: yesFarmacia Hospitalaria, 2019
Objective: To describe an injectable extended-release antipsychotic pharmacotherapeutic follow-up program and to assess adherence among patients included in the program.
Carmen Gallastegui   +5 more
doaj   +1 more source

Experimental pharmacological research regarding some newly synthesized benzamides on central nervous system functions [PDF]

open access: yes, 2017
Three newly synthesized benzamides by the Department of Pharmaceutical Chemistry of the Faculty of pharmacy from the University of Medicine and Pharmacy „Carol Davila” Bucharest were tested in order to determine whether these new molecules have similar ...
Chiriță, Cornel   +4 more
core   +8 more sources

Neuroleptic malignant syndrome

open access: yesJournal of Family Medicine and Primary Care, 2016
Neuroleptic malignant syndrome (NMS) is a life-threatening emergency that is often seen as a complication of antipsychotic agents. It is characterized by a tetrad of motor, behavioral, autonomic, and laboratory abnormalities.
Bino Rajamani   +2 more
doaj   +1 more source

Effects of intervention with the SAFE strategy on trachoma across Ethiopia.

open access: yes, 2011
BACKGROUND/AIMS: The impact of the SAFE strategy (surgery, antibiotics, face washing, environmental hygiene), recommended to eliminate blinding trachoma, is not well explored.
Patel, D   +3 more
core   +1 more source

Existing and emerging pharmacological approaches to the treatment of mania: A critical overview

open access: yesTranslational Psychiatry, 2022
Manic episodes are a defining, frequent and dramatically disabling occurrence in the course of Bipolar Disorder type I. Current pharmacotherapy of mania lists a good number of agents, but differences in efficacy and safety profiles among these agents ...
Giulio Sparacino   +3 more
doaj   +1 more source

Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]

open access: yes, 2006
It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko   +3 more
core   +1 more source

Potential role of peripheral and central vascular failure in neuroleptic, amphetamine and domperidone pharmacodynamics and toxicolog

open access: yesLiječnički vjesnik, 2023
Vascular failure is a pathological entity that seems to be antecedent to various pathological processes. This investigation theorized that vascular failure-related phenomena would be apparent in early phases after the application of neuroleptics ...
Ivan Maria Smoday   +2 more
doaj   +1 more source

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