Results 81 to 90 of about 25,654 (163)

Thiazolidine‐2,4‐dione and Thiazole Derivatives as Privileged Structures for Dengue Virus: A Review of Medicinal Chemistry Aspects

ChemistrySelect, Volume 11, Issue 37, 6 October 2026.
This graphical abstract summarizes thiazole, thiazolidine‐2,4‐dione, and hybrid compounds investigated as antiviral candidates against dengue virus. Representative structures and reported potencies are presented in the context of DENV serotypes. Proposed molecular targets include NS2B–NS3 protease and NS5.
Pedro César de Souza, Thaynara Paula Warren Bezerra, Matheus Vinicius Guimarães de Melo, Thayná da Silva Barros, Matheus Italo da Conceição, Michelle Melgarejo da Rosa, Moacyr Jesus Barreto de Melo Rêgo   +6 more
wiley   +1 more source

Antipyretic Activity of Stembark Extract of Mammea africana in Rats

Biology, Medicine & Natural Product Chemistry
Mammea africana Sabine (Guttiferae), is a tree plant whose parts are variously used locally for the treatment of various diseases such as malaria and fever among others. The stembark extract of M.
Jude E. Okokon, Chinyelu C. Osigwe, John A Udobang, Uwaeme Ugonma Florence   +3 more
doaj   +1 more source

Criteria for Safe Hospital Discharge in Bronchiolitis: A Systematic Review

Emergency Medicine Australasia, Volume 38, Issue 5, October 2026.
ABSTRACT Bronchiolitis is the leading cause of hospital presentation and admission for infants in Australasia. We aimed to synthesise current evidence on the effect of discharge criteria for infants (aged < 12 months) who are presenting to or are admitted to hospital with bronchiolitis, to inform a binational guideline recommendation update. Systematic
Meredith L. Borland, Kate Loveys, Franz E. Babl, Elizabeth Cotterell, Libby Haskell, Sharon O'Brien, Ed Oakley, Emma J. Tavender, Catherine L. Wilson, Stuart R. Dalziel, on behalf of the Paediatric Research in Emergency Departments International Collaborative (PREDICT) Network, Jane Alsweiler, David Armstrong, Simon Craig, Nigel Crawford, Dianne Crellin, Sonja Crone, Trevor Duke, Shane George, Christine Jeffries‐Stokes, Nidhi Krishnan, Ken Peacock, Tomas Ratoni, Peter Richmond, Annie Smith, Rebecca Starkie, David Thomas, Alexandra Wallace, Michael Zhang, Marian Chandler, Poh Chua   +30 more
wiley   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, Volume 95, Issue 4, Page 349-357, October 2026.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

Process optimization of macroporous resin purification of lignans from Fructus arctii and its antipyretic and analgesic effects

Siliao yanjiu
This study aimed to investigate the purification process of lignans from Fructus arctii using macroporous resin and evaluate their antipyretic and analgesic effects.
YAN Guoqing, ZENG Xueyan, YIN Huihui, HUANG Yunfu, JIANG Yuanming, LAN Tianyan, HE Shenhong, LIU Wei   +7 more
doaj  

Associations of Serum CIRP and CXCL5 With Prognosis and Neutrophil Extracellular Traps in Pediatric Mycoplasma pneumoniae Pneumonia

The Clinical Respiratory Journal, Volume 20, Issue 10, October 2026.
This study investigated serum levels of cold‐inducible RNA‐binding protein (CIRP) and C‐X‐C motif chemokine ligand 5 (CXCL5) in 485 children with Mycoplasma pneumoniae pneumonia. Elevated levels of both biomarkers were independently associated with poor prognosis and positively correlated with neutrophil extracellular trap markers, suggesting their ...
Litao Wan, Bolin Liu, Ning Xie, Jianhua Li, Ting Su, Liyan Zhang, Xiaohua Wang, Shiding Gao   +7 more
wiley   +1 more source

A primary healthcare approach to children with fever

South African Family Practice
A child with fever presenting with concerned caregivers is a common occurrence in primary healthcare in South Africa. Many fevers are self-limiting. However, serious and possibly fatal diseases must be excluded before discharging the child.
Indiran Govender, Henry I. Okonta
doaj   +1 more source

Seizures in children with Dravet syndrome in extreme heat: A qualitative study of parental perspectives

Developmental Medicine &Child Neurology, Volume 68, Issue 10, Page 1450-1459, October 2026.
Perspectives of parents of children with Dravet syndrome indicate that extreme heat and high temperatures exacerbate epileptic seizures, introduce new seizure triggers, and require the adoption of specific seizure‑management strategies. This original article is commented by Hood on pages 1338–1339 of this issue.
Angel Aledo‐Serrano, José Ángel Aibar, Domingo Palacios‐Ceña, Maria Salcedo‐Perez‐Juana, Maria Palacios‐Ceña, Simona Giorgi, Manuel Lorenzo‐Dieguez, Sanjay M Sisodiya, Cristina García‐Bravo   +8 more
wiley   +1 more source

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

Journal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English, Christine Huynh, William Roy, James W. Wynne, Hamish Rodger   +4 more
wiley   +1 more source

Anti-inflammatory, analgesic, and antipyretic potential of Oxystelma esculentum (L. f.) Sm. using in vitro, in vivo, and in silico studies

Frontiers in Pharmacology
The objective of the current study was to evaluate the anti-inflammatory, analgesic, and antipyretic potential of Oxystelma esculentum using different animal models.
Asmaa E. Sherif, Asmaa E. Sherif, Muhammad Sajid-ur-Rehman, Muhammad Asif, Iram Qadeer, Kashif ur Rehman Khan   +5 more
doaj   +1 more source