Anti-thyroid drugs in pediatric Graves′ disease
Indian Journal of Endocrinology and Metabolism, 2015 Graves′ disease is the most common cause of hyperthyroidism in children. Most children and adolescents are treated with anti-thyroid drugs as the initial modality.
Mathew John +2 more
doaj +1 more source
The natural history and prognostic factors of Graves' disease in Korean children and adolescents [PDF]
Korean Journal of Pediatrics, 2010 Purpose : Graves' disease is the most common cause of hyperthyroidism in children and adolescents. In this study, we investigated the natural course and the prognostic factors of Graves' disease in Korean children and ...
Seung Min Song +5 more
doaj +1 more source
Bioinorganic Chemistry in Thyroid Gland: Effect of\ud Antithyroid Drugs on Peroxidase-Catalyzed Oxidation\ud and Iodination Reactions [PDF]
, 2006 Propylthiouracil (PTU) and methimazole (MMI) are the most commonly used antithyroid drugs. The available data suggest that these drugs may block the thyroid hormone synthesis by inhibiting the thyroid peroxidase (TPO) or diverting oxidized iodides away ...
Mugesh, G. +5 more
core +1 more source
Nonthionamide Drugs for the Treatment of Hyperthyroidism: From Present to Future
International Journal of Endocrinology, 2018 Hyperthyroidism is a common endocrine disease. Although thionamide antithyroid drugs are the cornerstone of hyperthyroidism treatment, some patients cannot tolerate this drug class because of its serious side effects including agranulocytosis ...
Nattakarn Suwansaksri +2 more
doaj +1 more source
Elevated thyroid stimulating hormone in a neonate: Drug induced or disease?
Indian Journal of Endocrinology and Metabolism, 2011 Dyshormonogenesis is an uncommon cause of congenital hypothyroidism. The most common abnormality is absent or insufficient thyroid peroxidase enzyme. Maternal intake of antithyroid drug can also lead to elevated thyroid stimulating hormone (TSH) in a ...
Sunil Kumar Kota +2 more
doaj +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2017 Antithyroid drugs can be a rare cause of agranulocytosis (0.5% of treated patients). Suspension of these drugs is mandatory in these patients and may result in worsening hyperthyroidism.
Anna Candoni
doaj +1 more source
Cholestyramine Use for Rapid Reversion to Euthyroid States in Patients with Thyrotoxicosis [PDF]
Endocrinology and Metabolism, 2016 Cholestyramine (CS) is an ion exchange resin, which binds to iodothyronines and would lower serum thyroid hormone level. The use of CS added to conventional antithyroid drugs to control thyrotoxicosis has been applied since 1980's, and several studies ...
Jeonghoon Ha +4 more
doaj +1 more source
A case of thyrotoxic periodic paralysis as initial manifestation of Graves' disease in a 16-year-old Korean adolescent [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism, with recurrent muscle paralysis and hypokalemia that are caused by an intracellular shift of potassium.
Se Yong Jung +5 more
doaj +1 more source
Population-based studies of antithyroid drugs and sudden cardiac death
, 2009 WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Thyroid hormone free T4 is associated with QTc-interval prolongation, which is a risk factor for sudden cardiac death.
Hofman, A. (Albert) +11 more
core +1 more source
Pharmacodynamic Response to Anti-thyroid Drugs in Graves' Hyperthyroidism
Frontiers in Endocrinology, 2020 Objective: Graves' disease is the commonest cause of hyperthyroidism in populations with sufficient dietary iodine intake. Anti-thyroid drugs (ATD) are often used as the initial treatment for Graves' hyperthyroidism, however there is a paucity of data ...
Ali Abbara +22 more
doaj +1 more source