Effects of methimazole and propylthiouracil exposure during pregnancy on the risk of neonatal congenital malformations: A meta-analysis. [PDF]
PLoS ONE, 2017 The aim of this study was to determine the effect of exposure to different antithyroid drugs during pregnancy on the incidence of neonatal congenital malformations.A meta-analysis was performed to compare the incidence of neonatal congenital ...
Rongjing Song +4 more
doaj +1 more source
Effects of short-term potassium iodide treatment for thyrotoxicosis due to Graves disease in children and adolescents [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 PurposeGraves disease is the most common cause of hyperthyroidism in children. Inorganic iodide has been used in combination with antithyroid drugs for more effective normalization of thyroid hormones in some cases of severe thyrotoxicosis.
Kyung Uk Jeong +2 more
doaj +1 more source
The treatment of Graves' disease in children and adolescents [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 Graves' disease (GD) accounts for 10%-15% of thyroid disorders in children and adolescents. The use of antithyroid drugs as the initial treatment option in GD is well accepted.
Hae Sang Lee, Jin Soon Hwang
doaj +1 more source
Frontiers in Pharmacology, 2020 Background: Drugs can alter the gut microbiota structure, and gut microbiota dysbiosis in turn is correlated with drug side effects through the intestinal endotoxemia hypothesis.
Jiayu Sun +8 more
doaj +1 more source
Prevalence, Treatment Status, and Comorbidities of Hyperthyroidism in Korea from 2003 to 2018: A Nationwide Population Study [PDF]
Endocrinology and Metabolism, 2023 Background This study aimed to investigate the changes of incidence and treatment of choice for hyperthyroidism from 2003 to 2018 and explore the treatment-related complications and concomitant comorbidities in South Korea using data from the National ...
Hwa Young Ahn +6 more
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionRadioactive iodine (RAI) therapy is a critical component in the post-surgical management of thyroid cancer patients, as well as being a central therapeutic option in the treatment of hyperthyroidism.
Riazul Zannat +10 more
doaj +1 more source
Effect of Addition of Thyroxine in the Treatment of Graves’ Disease: A Systematic Review
Frontiers in Endocrinology, 2021 Graves’ disease is the most common cause of hyperthyroidism. Antithyroid drugs, radioiodine ablation, and surgery are the main treatments. Research has demonstrated that adding thyroxine to antithyroid therapy can improve the remission rate, and many ...
Jun Li +6 more
doaj +1 more source
A Case of Neonatal Thyrotoxicosis with Cardiac Insufficiency [PDF]
Neonatal Medicine, 2021 Neonatal thyrotoxicosis is rare and most of the cases are secondary to maternal Graves’ disease. It is usually transient, but can be associated with significant morbidity and mortality if not recognized promptly and treated adequately.
Ji Eun Jeong +4 more
doaj +1 more source
Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center. [PDF]
Medicines (Basel), 2020 Background: The most important series devoted to antithyroid drug-induced severe neutropenia and agranulocytosis are Japanese studies, almost specifically in relation to the intake of methimazole.
Andrès E +8 more
europepmc +2 more sources
Selenium analogues of antithyroid drugs - recent developments
, 2008 Thyroxine (T4), the main secretory hormone of the thyroid gland, is produced on thyroglobulin by thyroid peroxidase (TPO)/H2O2/iodide system and deiodinated to its active form (T3) by a selenocysteine-containing enzyme, iodothyronine deiodinase (ID). The
Mugesh, Govindasamy, Roy, Gouriprasanna
core +2 more sources