Factors affecting drug-induced liver injury: antithyroid drugs as instances [PDF]
Clinical and Molecular Hepatology, 2014 Methimazole and propylthiouracil have been used in the management of hyperthyroidism for more than half a century. However, hepatotoxicity is one of the most deleterious side effects associated with these medications.
Reza Heidari +3 more
doaj +3 more sources
Predicting remission of Graves' disease following treatment with antithyroid drugs [PDF]
Клинический разбор в общей медицине, 2023 Graves' disease (GD) is among the most prevalent organ-specific diseases and is one of the most common causes of hyperthyroidism in regions with normal iodine supply.
Natalya V. Drogashevskaya +5 more
doaj +2 more sources
Clinical characteristics of antithyroid drug-induced aplastic anemia cases over the past 30 years [PDF]
Frontiers in Endocrinology, 2023 ObjectiveThe authors aimed to investigate the clinical characteristics of antithyroid drug-induced aplastic anemia cases over the past 30 years.MethodsThe data of patients with antithyroid drug-induced aplastic anemia were retrieved from PubMed and ...
Ying Cheng +7 more
doaj +3 more sources
The effect of gender on response to antithyroid drugs and risk of relapse after discontinuation of the antithyroid drugs in patients with Graves’ hyperthyroidism: a multicentre study [PDF]
Endokrynologia Polska, 2020 INTRODUCTION: The outcome of medical treatment in patients with Graves’ disease (GD) is generally difficult to predict. In this study, we examined the hypothesis that gender may affect the outcome of treatment with antithyroid drugs (ATDs).
Sayid Shafi Zuhur +10 more
doaj +3 more sources
Antithyroid Drug-induced Agranulocytosis [PDF]
Journal of the Chinese Medical Association, 2009 Antithyroid drugs are widely used to treat hyperthyroidism, especially Graves' disease, but they tend to cause agranulocytosis, which increases the mortality rate. Granulocyte colony-stimulating factor decreases the duration of recovery from agranulocytosis.
Sun, Ming-Tsung +2 more
openaire +3 more sources
Exposure to antithyroid drugs and ethylenethiourea and risk of thyroid cancer: a systematic review of the epidemiologic evidence. [PDF]
Eur J Cancer Prev, 2022 Introduction: The thyroid peroxidase inhibiting compounds methimazole, methylthiouracil, propylthiouracil, thiouracil (i.e. 'antithyroid' drugs) and ethylenethiourea have been associated to thyroid tumours in rodents.
La Vecchia C, Turati F, Negri E.
europepmc +2 more sources
Risk Factors for Granulocytopenia in Patients with Graves' Disease Receiving Antithyroid Drugs. [PDF]
Int J Endocrinol, 2023 Objective. To study the risk factors for granulocytopenia caused by antithyroid drugs. Methods. Patients who were diagnosed with Graves’ hyperthyroidism and regularly treated with antithyroid drugs (ATDs) from January 2010 to July 2022 at Nanjing Drum ...
Li J, Zhang X, Li L, Zhu Q, Ge W, Ji C.
europepmc +2 more sources
Using plasma exchange to successfully manage thyrotoxicosis in a patient with possible antithyroid drug-related thrombotic thrombocytopenic purpura [PDF]
Endocrine Regulations, 2017 Objective. Thrombotic thrombocytopenic purpura (TTP) is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenic purpura, neurologic abnormalities, fever, and renal insufficiency.
Tazegul G +9 more
doaj +2 more sources
The Effect of Thyrotropin-Releasing Hormone and Antithyroid Drugs on Fetal Thyroid Function. [PDF]
Children (Basel), 2021 A euthyroid pregnant woman will normally have a fetus that displays normal fetal development. However, studies have long demonstrated the role of T3 (Triiodothyronine), T4 (Thyroxine), and TSH (Thyroid Stimulating Hormone) and their degree of ...
Vrachnis N +8 more
europepmc +4 more sources
Effects of short-term potassium iodide treatment for thyrotoxicosis due to Graves disease in children and adolescents [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 PurposeGraves disease is the most common cause of hyperthyroidism in children. Inorganic iodide has been used in combination with antithyroid drugs for more effective normalization of thyroid hormones in some cases of severe thyrotoxicosis.
Kyung Uk Jeong +2 more
doaj +1 more source