Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways
Toxins, 2016 Toxin-antitoxin (TA) modules are bacterial regulatory switches that facilitate conflicting outcomes for cells by promoting a pro-survival phenotypic adaptation and/or by directly mediating cell death, all through the toxin activity upon degradation of ...
Meenakumari Muthuramalingam +2 more
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Pantothenate kinase: A promising therapeutic target against pathogenic Clostridium species
HeliyonCurrent treatment of clostridial infections includes broad-spectrum antibiotics and antitoxins, yet antitoxins are ineffective against all Clostridiumspecies.
Soharth Hasnat +5 more
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ATP-Dependent Persister Formation in
mBio, 2017 Persisters are dormant variants that form a subpopulation of cells tolerant to antibiotics. Persisters are largely responsible for the recalcitrance of chronic infections to therapy.
Yue Shan +5 more
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Microtiter ganglioside enzyme-linked immunosorbent assay for vibrio and Escherichia coli heat-labile enterotoxins and antitoxin [PDF]
, 1980 David A. Sack +4 more
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Tetanus and diphtheria immunity in adolescents from São Paulo, Brazil
Brazilian Journal of Medical and Biological Research, 2007 Tetanus and diphtheria vaccines are of special concern in adolescents because boosters are necessary for adequate maintenance of protection and are often omitted.
M.I.S Dinelli +2 more
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Emerging Infectious Diseases, 2014 The Centers for Disease Control and Prevention convened panels of anthrax experts to review and update guidelines for anthrax postexposure prophylaxis and treatment. The panels included civilian and military anthrax experts and clinicians with experience
Katherine A. Hendricks +12 more
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Structural and functional studies of theMycobacterium tuberculosisVapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides [PDF]
, 2015 In-Gyun Lee +5 more
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HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation [PDF]
, 2020 Inga Songailienė +7 more
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SERS-Based Immunoassays for the Detection of Botulinum Toxins A and B Using Magnetic Beads
Sensors, 2019 Rapid and sensitive detection of botulinum neurotoxins (BoNTs) is important for immediate treatment with proper antitoxins. However, it is difficult to detect BoNTs at the acute phase of infection, owing to its rarity and ambiguous symptoms.
Kihyun Kim +4 more
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