Results 91 to 100 of about 37,127 (212)

Hepatitis C virus infection: a challenge in the complex management of two cases of multidrug-resistant tuberculosis

open access: yesBMC Infectious Diseases, 2019
Background Multidrug-resistant tuberculosis (MDR-TB) requires lengthy use of second-line drugs, burdened by many side effects. Hepatitis C virus (HCV) chronic infection increases risk of drug-induced liver injury (DILI) in these patients.
Maria Musso   +9 more
doaj   +1 more source

A real‐world experience with 6 months of antitubercular therapy in abdominal tuberculosis

open access: yesJGH Open, 2019
Abdominal tuberculosis is an important form of extrapulmonary tuberculosis. Evidence from clinical trials suggests that 6 months of antitubercular therapy (ATT) is sufficient for abdominal tuberculosis.
H. Mandavdhare   +3 more
semanticscholar   +1 more source

Emapalumab for Maladaptive Interferon‐γ‐Mediated Inflammation in Drug Reaction With Eosinophilia and Systemic Symptoms Complicating First‐Line Antituberculosis Therapy

open access: yes
Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
Yahya Almodallal   +4 more
wiley   +1 more source

Studies on new substituted pyridazinones: synthesis and biological evaluation

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2018
We report herein the synthesis and pharmacological evaluation of a new series of 6-aryl-2-(imidazol-1-yl/1,2,4-triazol-1-yl)-2-methyl-4,5-dihydro-(2H)-pyridazin-3-one (3a-j) as potential anticonvulsant and antitubercular agents.
Mohammad Asif   +3 more
doaj   +1 more source

Antitubercular Triazines: Optimization and Intrabacterial Metabolism [PDF]

open access: bronze, 2019
Xin Wang   +25 more
openalex   +1 more source

Development of Pseudomembranous Colitis Four Months after Initiation of Rifampicin

open access: yesCase Reports in Gastroenterology, 2011
Pseudomembranous colitis (PMC) may develop with long-term antibiotic administration, but is rarely reported to be caused by antitubercular agents. We present a case of PMC that occurred 120 days after starting rifampicin.
Jeong Moon Choi   +4 more
doaj   +1 more source

Pharmacophore, QSAR, molecular docking, molecular dynamics and ADMET study of trisubstituted benzimidazole derivatives as potent anti-tubercular agents

open access: yesChemical Physics Impact
The objective of this study was to develop and verify a QSAR model for predicting the antitubercular effects of trisubstituted benzimidazole derivatives. For this study, 50 compounds with antitubercular activity targeting FtsZ protein were retrieved from
Anguraj Moulishankar, T. Sundarrajan
doaj   +1 more source

Design of potent fluoro-substituted chalcones as antimicrobial agents

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2017
Owing to ever-increasing bacterial and fungal drug resistance, we attempted to develop novel antitubercular and antimicrobial agents. For this purpose, we developed some new fluorine-substituted chalcone analogs (3, 4, 9–15, and 20–23) using a structure ...
Serdar Burmaoglu   +8 more
doaj   +1 more source

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