Results 91 to 100 of about 50,974 (272)

Antibacterial and Antibiofilm Activity of 8‐Hydroxyquinoline Derivatives Against Mycobacterium and Staphylococcus Species

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Synthesis of 8‐hydroxyquinoline derivatives (QD 1‐12) from different analogues of 8‐hydroxyquinoline (HQ 1‐4). The derivatives and parent compounds were evaluated for antibacterial and antibiofilm activity against Mycobacterium tuberculosis, Mycobacterium smegmatis, methicillin‐resistant Staphylococcus aureus and methicillin‐sensitive Staphylococcus ...
Namrita Lall   +9 more
wiley   +1 more source

Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions [PDF]

open access: yes, 2017
Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), one of the top 10 causes of death worldwide in 2015. The recent emergence of strains resistant to all current drugs urges the development of compounds with new mechanisms of action ...
Lavezzo, Enrico   +7 more
core   +1 more source

Discovery and Biosynthesis of Atrovimycin, an Antitubercular and Antifungal Cyclodepsipeptide Featuring Vicinal-dihydroxylated Cinnamic Acyl Chain.

open access: yesOrganic Letters, 2019
Atrovimycin (1), a cyclodepsipeptide containing a unique vicinal-hydroxylated cinnamic acyl chain, was isolated and elucidated from Streptomyces atrovirens LQ13.
Qing Liu   +8 more
semanticscholar   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade   +4 more
wiley   +1 more source

Atypical clinical and imaging manifestation in neurocysticercosis

open access: yesAnnals of Indian Academy of Neurology, 2011
A 20-year-old man presented with left-sided headache and seizures of three years duration. Conglomerate ring-enhancing lesions were seen in the first magnetic resonance imaging study. He was initially treated with anticonvulsants for two years.
L Dayananda   +4 more
doaj   +1 more source

(E)-N'-(2, 4-dihydroxybenzylidene)nicotinohydrazide and its Metal Complexes: Synthesis, Characterisation and Antitubercular Activity [PDF]

open access: yes, 2016
Nicotinic acid hydrazide and 2,4-dihydoxylbenzaldehyde were condensed at 20 °C to form an acylhydrazone (H3L1) with ONO coordination pattern. The structure of the acylhydrazone was elucidated by using CHN analyzer, ESI mass spectrometry, IR, 1H NMR, 13C ...
Adekoya, J. A.
core  

Ionophoric effects of the antitubercular drug bedaquiline

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Antibiotics generally target one of five essential cellular functions in bacteria, but many of these targets are now compromised through rapidly spreading antibiotic resistance.
Kiel Hards   +6 more
semanticscholar   +1 more source

Rapidly Progressive Multiple System Atrophy—Cerebellar Type in a 52‐Year‐Old Woman: Diagnostic Challenges in a Resource‐Limited Setting

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Multiple system atrophy (MSA) is a progressive adult‐onset neurodegenerative disorder that manifests as a variable combination of cerebellar, parkinsonian, and autonomic dysfunctions. We report a case of a 52‐year‐old woman who presented with rapidly progressive gait ataxia, dysarthria, orthostatic hypotension, and urinary urgency.
Khushi V. Singh   +8 more
wiley   +1 more source

PYRAZINAMIDE INDUCED ACUTE GOUTY ARTHRITIS

open access: yesJournal of Nepal Medical Association, 2003
A typical case of pyrazinamide induced acute gouty arthritis in a tuberculous patient with antitubercular therapy including pyrazinamide was reported.
U N Pathak, B O Shrestha, R R Shrestha
doaj   +1 more source

Isolated tuberculosis of the posterior spinal elements: case report and discussion of management [PDF]

open access: yes, 2014
In neurologically intact patients with isolated tuberculosis of the posterior spinal elements, surgical intervention can be of benefit in select patients by reducing instability, deformity and late ...
Al-Khudairi, N., Meir, A.
core   +1 more source

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