Results 81 to 90 of about 26,304 (200)

Screening of the antimycobacterial activity of novel lipophilic agents by the modified broth based method

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2016
Most of the introduced susceptibility methods of Mycobacterium tuberculosis have some disadvantages for screening. Therefore, the selection of susceptibility assay for evaluating candidate agents must be determined case by case.
Mehdi Zandhaghighi, Kiarash Ghazvini, Zahra Meshkat, Seyed Abdolrahim Rezaee, Mohammad Derakhshan, Saman Soleimanpour, Farzin Hadizadeh   +6 more
doaj   +1 more source

Liver transplantation for acute liver failure due to antitubercular drugs – a single-center experience

Clinics, 2018
OBJECTIVES: Patients receiving treatment for tuberculosis are at risk of developing acute liver failure due to the hepatotoxicity of antitubercular drugs.
Rodrigo Bronze de Martino, Edson Abdala, Felipe Castro Villegas, Luiz Augusto Carneiro D’Albuquerque, Alice Tung Wan Song   +4 more
doaj   +1 more source

Synthesis, antimicrobial and antitubercular activities of some novel pyrazoline derivatives

, 2016
In the present study, two new series of pyrazolines (3a–h & 4a–h) were synthesized starting from p-acetamidophenol (paracetamol) and evaluated for their antibacterial, antifungal and antitubercular activities.
Aftab Ahmad, Asif Husain, Shah Alam Khan, Khan, Shah Alam, Mujeeb, Mohd., Husain, Asif, Bhandari, Anil, Ahmad, Aftab, Mohd. Mujeeb, Anil Bhandari   +9 more
core   +1 more source

Antitubercular Benzothiazinones - synthesis, activity, properties and SAR [PDF]

, 2014
Tuberkulose ist eine der weltweit am meisten verbreitete Infektionskrankheit, der jährlich 1.3 Mio. Menschen zum Opfer fallen. Besorgniserregend ist der Anstieg multiresistenter Fälle, auch in Industrienationen.
Rudolph, Andrea Ines
core   +1 more source

Synthesis, Antimicrobial and Antitubercular Activities of Some Novel Trihydroxy Benzamido Azetidin-2-one Derivatives

, 2011
Purpose: To synthesize and characterize novel trihydroxy benzamido azetidin-2-one derivatives and screen them for antimicrobial and antitubercular activities. Methods: A series of novel 4-aryl-3-chloro-N-(3,4,5-trihydroxy benzamido)-2-azetidinones, 3a-
Arunkumar, S, Ilango, K
core   +3 more sources

Effect of goat milk on hepatotoxicity induced by antitubercular drugs in rats

, 2016
Aim of the present study was to assess the hepatoprotective activity of goat milk on antitubercular drug-induced hepatotoxicity in rats. Hepatotoxicity was induced in rats using a combination of isoniazid, rifampicin, and pyrazinamide given orally as a ...
Rakesh Raman Patyar, Sonam Miglani, Sazal Patyar, Patyar, Sazal, Patyar, Rakesh Raman, Reshi, Mohammad Rafi, Miglani, Sonam, Mohammad Rafi Reshi   +7 more
core   +1 more source

Derivatives of pyrazine as potencial antitubercular drugs

, 2011
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical chemistry and drug control Candidate Mgr. Lukáš Dobrovolný Consultant Doc. PharmDr. Martin Doležal, Ph.D.
Dobrovolný, Lukáš
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Antitubercular agents. Part 1: Synthesis of phthalimido- and naphthalimido-linked phenazines as new prototype antitubercular agents

, 2005
The preparation and antitubercular properties of a series of phthalimido- and naphthalimido-linked phenazines are described. Some of these new compounds inhibited the growth of Mycobacterium tuberculosis ATCC 27294, Mycobacterium avium ATCC 49601 ...
Sinha, Rakesh, Arora, Sudarshan K., Kamal, Ahmed, Yadav, J. S., Hari Babu, A., Venkata Ramana, A.   +5 more
core   +1 more source

Management of Hepatotoxicity and Utilization of Antitubercular Drugs in Chronic Liver Disease: A Narrative Review

Journal of Nepal Medical Association
The World Health Organization’s “End TB strategy” envisions a world free of tuberculosis (TB), emphasizing early diagnosis, effective treatment, and prevention.
Pratap Sagar Tiwari, Pukar Thapa
doaj   +1 more source

Synthesis of substituted nitrogen heterocycles as potential antitubercular agents [PDF]

, 2019
Charles University Faculty of Pharmacy in Hradec Králové Candidate: Mgr. Jan Němeček Supervisor: Assoc. Prof. PharmDr. Jaroslav Roh, PhD Title of doctoral thesis: Synthesis of substituted nitrogen heterocycles as potential antitubercular agents ...
Němeček, Jan
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