Results 61 to 70 of about 26,304 (200)
Advanced Healthcare Materials, Volume 15, Issue 14, 10 April 2026.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Quality of the life of the TB patients
Кубанский научный медицинский вестник, 2015 In the article the results of studying the quality of the life of patients with tuberculosis are represented. By the authors were interviewed 500 patients GBUz SK «Boundary antitubercular dispensary» (g. Stavropol').
V. B. Zafirova +3 more
doaj
Asian Journal of Organic Chemistry, Volume 15, Issue 4, April 2026.A practical and efficient CBr4‐mediated metal‐free route for sulfonamide synthesis is presented under batch, ultrasonic, and continuous‐flow conditions. The protocol demonstrates excellent substrate scope, reduced reaction times, and mild operating conditions, highlighting a scalable alternative to traditional iodine‐mediated methods in modern ...
Alageswaran Jayaram +6 more
wiley +1 more source
The Synthesis and Evaluation of N-Heterocycles as Antitubercular Agents
, 2021 Tuberculosis, the disease caused by the microbial pathogen Mycobacterium tuberculosis, is one of the world’s leading infectious causes of death. In 2019, the World Health Organisation estimated that 10 million new cases of tuberculosis were contracted ...
Martin, Liam Thomas
core
British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1058-1068, April 2026.Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding +6 more
wiley +1 more source
Novel 1,4-substituted-1,2,3-triazoles as antitubercular agents.
, 2023 Tuberculosis (TB) remains a pressing unmet medical need, particularly with the emergence of multidrug-resistant and extensively drug-resistant tuberculosis.
Luke Henderson (13082367) +4 more
core
Frontiers in Pharmacology, 2018 Tuberculosis is one of the leading cause of death worldwide, particularly due to evolution of drug resistant strains. Antitubercular peptides may provide an alternate approach to combat antibiotic tolerance.
Salman Sadullah Usmani +4 more
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.ABSTRACT Due to limited access to, and the high cost of conventional veterinary services, Batswana communities often rely on ethnoveterinary practices for livestock health management. This review provides an in‐depth analysis on the ethnoveterinary uses, biological properties and safety assessment of plants utilised in livestock husbandry. A systematic
Tswelelopele G. Mpolokeng +7 more
wiley +1 more source
, 2009 Background: Tuberculosis (TB) is the most common opportunistic infection in children with human immunodeficiency virus (HIV) infection in developing countries, and co-treatment for HIV infection and TB is frequently indicated.
Ren, Yuan
core
Efficient Mutasynthesis of “Non-Natural” Antitubercular Ilamycins with Low Cytotoxicity
Ilamycins are a type of cyclopeptide exhibiting potent antitubercular and cytotoxic activities, which make them promising leads for antitubercular and antitumor drugs with unique mechanisms.
Yingying Chen (500738) +11 more
core +1 more source