Results 41 to 50 of about 23,044 (143)

Ligand-based discovery of novel N-arylpyrrole derivatives as broad-spectrum antimicrobial agents with antibiofilm and anti-virulence activity

Journal of Enzyme Inhibition and Medicinal Chemistry
The escalating threat of antimicrobial resistance calls for novel therapeutic agents. This study employed a ligand-based design approach to develop three series of N-arylpyrrole derivatives (Va–e, VIa–e, and VIIa–e), refined through molecular modeling ...
Basma M. Qandeel, Samar Mowafy, Mohamed F. El-Badawy, Nahla A. Farag, Galal Yahya, Khaled Abouzid   +5 more
doaj   +1 more source

Screening of the antimycobacterial activity of novel lipophilic agents by the modified broth based method

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2016
Most of the introduced susceptibility methods of Mycobacterium tuberculosis have some disadvantages for screening. Therefore, the selection of susceptibility assay for evaluating candidate agents must be determined case by case.
Mehdi Zandhaghighi, Kiarash Ghazvini, Zahra Meshkat, Seyed Abdolrahim Rezaee, Mohammad Derakhshan, Saman Soleimanpour, Farzin Hadizadeh   +6 more
doaj   +1 more source

Liver transplantation for acute liver failure due to antitubercular drugs – a single-center experience

Clinics, 2018
OBJECTIVES: Patients receiving treatment for tuberculosis are at risk of developing acute liver failure due to the hepatotoxicity of antitubercular drugs.
Rodrigo Bronze de Martino, Edson Abdala, Felipe Castro Villegas, Luiz Augusto Carneiro D’Albuquerque, Alice Tung Wan Song   +4 more
doaj   +1 more source

Management of Hepatotoxicity and Utilization of Antitubercular Drugs in Chronic Liver Disease: A Narrative Review

Journal of Nepal Medical Association
The World Health Organization’s “End TB strategy” envisions a world free of tuberculosis (TB), emphasizing early diagnosis, effective treatment, and prevention.
Pratap Sagar Tiwari, Pukar Thapa
doaj   +1 more source

Pharmacophore, QSAR, molecular docking, molecular dynamics and ADMET study of trisubstituted benzimidazole derivatives as potent anti-tubercular agents

Chemical Physics Impact
The objective of this study was to develop and verify a QSAR model for predicting the antitubercular effects of trisubstituted benzimidazole derivatives. For this study, 50 compounds with antitubercular activity targeting FtsZ protein were retrieved from
Anguraj Moulishankar, T. Sundarrajan
doaj   +1 more source

Antituberculars

Reactions Weekly, 2022
  +5 more sources

Rifampicin-induced Secondary Hyperparathyroidism in a Case of Isoniazid Monoresistant Pulmonary Tuberculosis

The Journal of Association of Chest Physicians
Antitubercular drug (ATD)-induced hypovitaminosis D3 and secondary hyperparathyroidism are less reported phenomena compared to other antitubercular therapy–induced adverse events.
Indra Kishor Saha, Rohan Malakar, Anubha Biswas, Saptarshi Goswami   +3 more
doaj   +1 more source

Penile Papulonecrotic Tuberculide

Indian Journal of Dermatology, 2003
A 38 year old male presented with an eight year history of recurrent popular eruptions followed by ulceration and scarring on glans penis. Based on histopathological examination, a diagnosis of papulonecrotic tuberculide was made.
Rana Sandeep, D′ Souza Paschal, Khare Ashok Kumar, Meena Ram Singh, Meherda Ashok, Purohit Sanjay, Nuwal Paras   +6 more
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The treatment of ocular tuberculosis: A survey of published literature

Indian Journal of Ophthalmology, 2006
With an expanding awareness of ocular tuberculosis, ophthalmologists are increasingly required to participate in the care of these patients. We conducted a survey of published ophthalmic literature to identify whether the regimens of antitubercular ...
Mehta Salil
doaj  

Rational design and synthesis of novel diphenyl ether derivatives as antitubercular agents

Drug Design, Development and Therapy, 2016
Sidhartha S Kar,1 Varadaraj Bhat G,1 Praveen PN Rao,2 Vishnu P Shenoy,3 Indira Bairy,4 G Gautham Shenoy1 1Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, India; 2School of Pharmacy, Health
Kar SS, Bhat G V, Rao PP, Shenoy VP, Bairy I, Shenoy GG   +5 more
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