Results 31 to 40 of about 27,938 (191)

Tandem LC-MS Identification of Antitubercular Compounds in Zones of Growth Inhibition Produced by South African Filamentous Actinobacteria

open access: yesMolecules, 2023
Novel antitubercular compounds are urgently needed to combat drug-resistant Mycobacterium tuberculosis (Mtb). Filamentous actinobacteria have historically been an excellent source of antitubercular drugs.
Daniel J. Watson   +4 more
doaj   +1 more source

Design, Facile Synthesis and Characterization of Dichloro Substituted Chalcones and Dihydropyrazole Derivatives for Their Antifungal, Antitubercular and Antiproliferative Activities

open access: yesMolecules, 2020
Infectious diseases caused by fungi and mycobacteria pose an important problem for humankind. Similarly, cancer is one of the leading causes of death globally.
Afzal B. Shaik   +6 more
doaj   +1 more source

Antitubercular activities of the novel synthesized 1,2,4-triazole derivatives

open access: yes, 2021
1 2 4-Triazole; Antitubercular activities ...
신윤용, 김대기, 박혜영
core   +1 more source

Antioxidant, Antitubercular and Cytotoxic Activities of Piper imperiale

open access: yesMolecules, 2012
Phenolic compounds are widely distributed in Nature and act as pharmacologically active constituents in many herbal medicines. They have multiple biological properties, most notably antioxidant, antibacterial and cytotoxic activities.
Sanjib Bhakta   +6 more
doaj   +1 more source

Synthesis, Antibacterial and Antitubercular Activities of Some 5H-Thiazolo[3,2-a]pyrimidin-5-ones and Sulfonic Acid Derivatives

open access: yesMolecules, 2015
A series of 5H-thiazolo[3,2-a]pyrimidin-5-ones were synthesized by the cyclization reactions of S-alkylated derivatives in concentrated H2SO4. Upon treatment of S-alkylated derivatives at different temperatures, intramolecular cyclization to 7 ...
Dong Cai   +6 more
doaj   +1 more source

Fluorinated chalcones, pyridine and pyran derivatives with significant antitubercular activity.

open access: yes, 2022
Fluorinated chalcones, pyridine and pyran derivatives with significant antitubercular activity.
M. Mukhlesur Rahman (2100193)   +7 more
core   +1 more source

Synthesis and Biological Evaluation of 2-(3-Fluoro-4-nitro phenoxy)-N-phenylacetamide Derivatives as Novel Potential Affordable Antitubercular Agents

open access: yesMolecules, 2012
A novel series of 2-(3-fluoro-4-nitrophenoxy)-N-phenylacetamide compounds were designed, synthesized and in vitro assessed for their antitubercular activities by a microdilution method.
Yu-Quan Wei   +8 more
doaj   +1 more source

The Plasma, Whole Blood and Intracellular Concentrations of Antiretroviral Agents in South African Children Receiving Combination Antiretroviral Therapy with and without Concomitant Antitubercular Treatment [PDF]

open access: yes, 2009
Background: Tuberculosis (TB) is the most common opportunistic infection in children with human immunodeficiency virus (HIV) infection in developing countries, and co-treatment for HIV infection and TB is frequently indicated.
Ren, Yuan
core   +1 more source

The Synergistic Effects of the Glutathione Precursor, NAC and First-Line Antibiotics in the Granulomatous Response Against Mycobacterium tuberculosis

open access: yesFrontiers in Immunology, 2018
Mycobacterium tuberculosis (M. tb), the causative bacterial agent responsible for tuberculosis (TB) continues to afflict millions of people worldwide. Although the human immune system plays a critical role in containing M.
Garrett Teskey   +14 more
doaj   +1 more source

Mechanochemical Synthesis and Physicochemical Characterization of Isoniazid and Pyrazinamide Co-crystals With Glutaric Acid

open access: yesFrontiers in Chemistry, 2020
The present work reports two novel pharmaceutical co-crystals; 2:1 isoniazid-glutaric acid (INHGA) and 2:1 pyrazinamide-glutaric acid (PGA). Isoniazid and pyrazinamide are key first-line drugs used for the treatment of tuberculosis.
Jean Baptiste Ngilirabanga   +3 more
doaj   +1 more source

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