Results 21 to 30 of about 27,938 (191)
Development of 6Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents
, 2022 The 6-trifluoro substituted 8-nitrobenzothiazinones (BTZs) represent a novel type of antitubercular agents, and their high antimycobacterial activity is related to the inhibition of decaprenylphosphoryl-β-d-ribose 2′-oxidase (DprE1), an enzyme essential ...
Bin Wang +19 more
core +3 more sources
Antitubercular and Antiparasitic 2-Nitroimidazopyrazinones with Improved Potency and Solubility. [PDF]
, 2020 Following the approval of delamanid and pretomanid as new drugs to treat drug-resistant tuberculosis, there is now a renewed interest in bicyclic nitroimidazole scaffolds as a source of therapeutics against infectious diseases.
Sykes, Melissa L +16 more
core +1 more source
Intestinal Perforation as a Paradoxical Reaction to Antitubercular Therapy: A Case Report [PDF]
Annals of Coloproctology, 2021 Paradoxical reactions to tuberculosis (TB) treatment are characterized by an initial improvement of the clinical symptoms followed by clinical or radiological deterioration of existing tuberculous lesions, or by development of new lesions.
Sung Hoon Kang +10 more
doaj +1 more source
Pyrimidine derivatives with antitubercular activity [PDF]
, 2023 Small molecules with antitubercular activity containing the pyrimidine motif in their structure have gained more attention after three drugs, namely GSK 2556286 (GSK-286), TBA-7371 and SPR720, have entered clinical trials.
Roh, Jaroslav +5 more
core +1 more source
Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
Pharmaceuticals, 2020 This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina +3 more
doaj +1 more source
PYRAZOLINES AS POTENT ANTITUBERCULAR AND CYTOTOXIC AGENTS [PDF]
, 2017 Objective: Pyrazolines are known to exhibit different biological and pharmacological properties such as anticancer, antibacterial, antifungal and antitubercular activities.
K, Ishwar Bhat, Kumar, Abhishek
core +3 more sources
Бюллетень сибирской медицины, 2015 Due to the high incidence of tuberculosis of women of reproductive age research at 270 patients was conducted. The group of research included women with infertility and genital tuberculosis, pregnant women with active tuberculosis of lungs, pregnant ...
A. V. Mordyk +3 more
doaj +1 more source
Molecules, 2021 A ChCl: Gly (DESs) promoted environmentally benign method was developed for the first time using the reaction of aryl aldehydes and dimedone to give excellent yields of xanthene analogues.
Mashooq A. Bhat +4 more
doaj +1 more source
Pleurisy in tuberculosis and HIV-infected patients
Журнал инфектологии, 2014 A clinical and epidemiological study for 14 years was conducted. Among TB patients, the percentage of persons with mixed infection (TB+HIV infection) increased during the observation period from 10 up to 64%. About one third of them had a pleura reaction
A. K. Ivanov +6 more
doaj +1 more source
Molecules, 2021 Antimicrobial resistance was one of the top priorities for global public health before the start of the 2019 coronavirus pandemic (COVID-19). Moreover, in this changing medical landscape due to COVID-19, finding new organic structures with antimicrobial ...
Maria Marinescu
doaj +1 more source