Results 71 to 80 of about 27,938 (191)

Investigating the Inhibitory Properties of Diazo and Pyrazole‐Carboxamide‐Linked Benzenesulfonamides Against Carbonic Anhydrase Isoforms I, II, IX, and XII

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
Hybrid diazo‐ and pyrazole‐carboxamide benzenesulfonamides emerge as highly potent and selective inhibitors of tumor‐associated carbonic anhydrases. A 3,4‐dichloro‐substituted derivative achieves sub‐2 nM inhibition of hCA IX and displays promising anticancer activity, revealing a valuable scaffold for the development of next‐generation cancer‐targeted
Suleyman Akocak   +8 more
wiley   +1 more source

A facile synthesis, antibacterial, and antitubercular studies of some piperidin-4-one and tetrahydropyridine derivatives

open access: yes, 2008
The raise in clinical significance of multidrug-resistant bacterial pathogens has directed us to synthesize 2,6-diarylpiperidin-4-one and Δ3-tetrahydropyridin-4-ol based benzimidazole and O-arylsulfonyl derivatives.
Amirthaganesan, Shanmugasundaram   +7 more
core   +1 more source

Quality of the life of the TB patients

open access: yesКубанский научный медицинский вестник, 2015
In the article the results of studying the quality of the life of patients with tuberculosis are represented. By the authors were interviewed 500 patients GBUz SK «Boundary antitubercular dispensary» (g. Stavropol').
V. B. Zafirova   +3 more
doaj  

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia   +4 more
wiley   +1 more source

Structures of CpIMPDH inhibitors with antitubercular activity.

open access: yes, 2015
Structures of CpIMPDH inhibitors with antitubercular activity.
Andrzej Joachimiak (143860)   +13 more
core   +1 more source

Prediction of Antitubercular Peptides From Sequence Information Using Ensemble Classifier and Hybrid Features

open access: yesFrontiers in Pharmacology, 2018
Tuberculosis is one of the leading cause of death worldwide, particularly due to evolution of drug resistant strains. Antitubercular peptides may provide an alternate approach to combat antibiotic tolerance.
Salman Sadullah Usmani   +4 more
doaj   +1 more source

Atypical clinical and imaging manifestation in neurocysticercosis

open access: yesAnnals of Indian Academy of Neurology, 2011
A 20-year-old man presented with left-sided headache and seizures of three years duration. Conglomerate ring-enhancing lesions were seen in the first magnetic resonance imaging study. He was initially treated with anticonvulsants for two years.
L Dayananda   +4 more
doaj   +1 more source

Novel 1,4-substituted-1,2,3-triazoles as antitubercular agents.

open access: yes, 2023
Tuberculosis (TB) remains a pressing unmet medical need, particularly with the emergence of multidrug-resistant and extensively drug-resistant tuberculosis.
Luke Henderson (13082367)   +4 more
core  

Histomorphological features of combined forms of tuberculosis and lung cancer [PDF]

open access: yesMedičnì Perspektivi, 2017
The were studied pathological features of combined forms of tuberculosis and non-small cell lung cancer in 72 patients who underwent radical surgical resection interventions from transsternal access with mediastinal lymph node dissection, with ...
Savenkov Y.F.   +4 more
doaj  

PYRAZINAMIDE INDUCED ACUTE GOUTY ARTHRITIS

open access: yesJournal of Nepal Medical Association, 2003
A typical case of pyrazinamide induced acute gouty arthritis in a tuberculous patient with antitubercular therapy including pyrazinamide was reported.
U N Pathak, B O Shrestha, R R Shrestha
doaj   +1 more source

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