Results 91 to 100 of about 26,304 (200)

Novel 1,4-substituted-1,2,3-triazoles as antitubercular agents.

, 2015
Tuberculosis (TB) remains a pressing unmet medical need, particularly with the emergence of multidrug-resistant and extensively drug-resistant tuberculosis.
Luke Henderson (13082367), JM Altimari (14466177), A Sajid (13410789), SC Hockey (14527817), HI Boshoff (18718477)   +4 more
core  

Pharmacophore, QSAR, molecular docking, molecular dynamics and ADMET study of trisubstituted benzimidazole derivatives as potent anti-tubercular agents

Chemical Physics Impact
The objective of this study was to develop and verify a QSAR model for predicting the antitubercular effects of trisubstituted benzimidazole derivatives. For this study, 50 compounds with antitubercular activity targeting FtsZ protein were retrieved from
Anguraj Moulishankar, T. Sundarrajan
doaj   +1 more source

Antitubercular Sesterterpenes from the Thai Sponge Brachiaster sp.

, 2016
A new scalarane-type sesterterpene, 12-deacetoxyscalarin 19-acetate (2), and two naturally new derivatives of manoalide-type sesterterpenes, (E)- and (Z)-neomanoalide 24,25-diacetates (3 and 4), were isolated from the Thai sponge Brachiaster sp., along ...
Anuchit Plubrukarn (1880524), Niwat Keawpradub (2704453), Supreeya Yuenyongsawad (1773295), Saeng-ngam Wonganuchitmeta (2704456)   +3 more
core   +1 more source

Rifampicin-induced Secondary Hyperparathyroidism in a Case of Isoniazid Monoresistant Pulmonary Tuberculosis

The Journal of Association of Chest Physicians
Antitubercular drug (ATD)-induced hypovitaminosis D3 and secondary hyperparathyroidism are less reported phenomena compared to other antitubercular therapy–induced adverse events.
Indra Kishor Saha, Rohan Malakar, Anubha Biswas, Saptarshi Goswami   +3 more
doaj   +1 more source

4-Aminoquinoline-β-Lactam Conjugates: Synthesis, Antimalarial, and Antitubercular Evaluation

, 2014
A library of quinoline-β-lactam-based hybrids was synthesized and tested for their antimalarial and antitubercular activities. The present antimalarial data showed the dependence of activity on the nature of linker, N-1 substituent of the β-lactam ring ...
Rosenthal, Philip J, Gut, Jiri, Carrère-Kremer, Séverine, Kumar, Vipan, Kremer, Laurent, Raj, Raghu, Biot, Christophe, Guerardel, Yann   +7 more
core   +1 more source

Synthesis of Adamantane Aminoethers with Antitubercular Potential

Background: Intrigued by the fact that aminoadamantane derivatives, bearing the active 1,2-ethylenediamine moiety, are promising antitubercular agents, we report herein the synthesis and the antitubercular evaluation of N,N'-substituded-4,4'-[adamantane ...
Papanastasiou, Ioannis, Vocat, Anthony, Cole, Stewart T., Foscolos, Angeliki-Sofia, Foscolos, George B., Tsotinis, Andrew, Kolocouris, Nicolas   +6 more
core   +1 more source

Antituberculars

Reactions Weekly, 2022
  +5 more sources

Synthesis and evaluation of some new substituted phenylthiazole derivatives and their antitubercular activity

, 2009
1033-1037A new series of substituted phenylthiazole derivatives have been synthesized and the structures of these compounds have been established on the basis of spectral and elemental analysis.
Bukitagar, Anand A, Jayashri S. Pattan, Anand A. Bukitagar, Pattan, Shashikant R, B. P. Kapadnis, S. G. Jadhav, Kapadnis, B P, Shashikant R. Pattan, Pattan, Jayashri S, Jadhav, S G   +9 more
core   +1 more source

Synthesis and Antitubercular Activity of 4-Thiazolidinone Derivatives

, 1992
Chemistry Department. B. K. M. Science College. Valsad-396 001 Manuscript received 30 May 1991. revised 22 July 1992, accepted 10 August 1992 Synthesis and Antitubercular Activity of 4-Thiazolidinone ...
K. M. KAPADIA, C. M.DESAI, A. N. SOLANKEE   +2 more
core   +1 more source

Central Nervous System Infections Caused by Bacillus Calmette–Guerin: Case Report and Narrative Literature Review

Microorganisms
Bacillus Calmette–Guerin (BCG) central nervous system (CNS) infections are one of the rarest complications following BCG exposure. A 77-year-old male, with bladder cancer previously treated with BCG instillation, presented with fever, confusion, and ...
Davide Chemello, Maddalena Albertini, Johanna Chester, Sara Esperti, Elena Ghidoni, Gabriella Orlando, Giacomo Franceschi, Corrado Iaccarino, Lucio Lucchesi, Giacomo Pavesi, Cristina Mussini, Erica Franceschini   +11 more
doaj   +1 more source