Results 91 to 100 of about 27,938 (191)

Synthesis of substituted nitrogen heterocycles as potential antitubercular agents [PDF]

, 2019
Charles University Faculty of Pharmacy in Hradec Králové Candidate: Mgr. Jan Němeček Supervisor: Assoc. Prof. PharmDr. Jaroslav Roh, PhD Title of doctoral thesis: Synthesis of substituted nitrogen heterocycles as potential antitubercular agents ...
Němeček, Jan
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Synthesis, Antimicrobial and Antitubercular Activities of Some Novel Trihydroxy Benzamido Azetidin-2-one Derivatives [PDF]

, 2011
Purpose: To synthesize and characterize novel trihydroxy benzamido azetidin-2-one derivatives and screen them for antimicrobial and antitubercular activities. Methods: A series of novel 4-aryl-3-chloro-N-(3,4,5-trihydroxy benzamido)-2-azetidinones, 3a-
Arunkumar, S, K Ilango, Ilango, K, S Arunkumar   +3 more
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Management of Hepatotoxicity and Utilization of Antitubercular Drugs in Chronic Liver Disease: A Narrative Review

Journal of Nepal Medical Association
The World Health Organization’s “End TB strategy” envisions a world free of tuberculosis (TB), emphasizing early diagnosis, effective treatment, and prevention.
Pratap Sagar Tiwari, Pukar Thapa
doaj   +1 more source

Synthesis, antitubercular evaluation and molecular docking studies of phthalimide bearing 1,2,3-triazoles

, 2019
In a search for safer and potent antitubercular agents, here a library of newly substituted dioxoisoindolinylmethyl-triazolyl-N-phenylacetamide derivatives (5a–l) has been synthesized via click chemistry approach. All synthesized compounds were evaluated
Lalita K. Dahiwade (6706424), Prafulla B. Choudhari (6706427), Rajubai D. Bakale (6706421), Pramod S. Phatak (6706418), Sambhaji T. Dhumal (6276344), Kishan P. Haval (2420878), Dharmarajan Sriram (816698), Vagolu Siva Krishna (6706430)   +7 more
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Construction and functionalization of fused pyridine ring leading to novel compounds as potential antitubercular agents

, 2012
A series of fused and functionalized pyridine derivatives were designed, synthesized and tested for their potential antitubercular properties. All these novel compounds were prepared by using multistep methods involving the construction of pyridine ring ...
Kapavarapu, Ravikumar, Reiser, Oliver, Wan, Baojie, Iqbal, Javed, Pal, Manojit, Dulla, Balakrishna, Franzblau, Scott G.   +6 more
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Pharmacophore, QSAR, molecular docking, molecular dynamics and ADMET study of trisubstituted benzimidazole derivatives as potent anti-tubercular agents

Chemical Physics Impact
The objective of this study was to develop and verify a QSAR model for predicting the antitubercular effects of trisubstituted benzimidazole derivatives. For this study, 50 compounds with antitubercular activity targeting FtsZ protein were retrieved from
Anguraj Moulishankar, T. Sundarrajan
doaj   +1 more source

Antitubercular agents. Part 1: Synthesis of phthalimido- and naphthalimido-linked phenazines as new prototype antitubercular agents

, 2005
The preparation and antitubercular properties of a series of phthalimido- and naphthalimido-linked phenazines are described. Some of these new compounds inhibited the growth of Mycobacterium tuberculosis ATCC 27294, Mycobacterium avium ATCC 49601 ...
Sinha, Rakesh, Arora, Sudarshan K., Kamal, Ahmed, Yadav, J. S., Hari Babu, A., Venkata Ramana, A.   +5 more
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Evaluation of antitubercular drug insertion into preformed dipalmitoylphosphatidylcholine monolayers

, 2008
Insertion profiles of antitubercular drugs isoniazid (INH), rifampicin (RFM) and ethambutol (ETH) into dipalmitoylphosphatidylcholine (DPPC) membrane models were evaluated by Langmuir monolayer technique.
CHIMOTE, G, BANERJEE, R
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Rifampicin-induced Secondary Hyperparathyroidism in a Case of Isoniazid Monoresistant Pulmonary Tuberculosis

The Journal of Association of Chest Physicians
Antitubercular drug (ATD)-induced hypovitaminosis D3 and secondary hyperparathyroidism are less reported phenomena compared to other antitubercular therapy–induced adverse events.
Indra Kishor Saha, Rohan Malakar, Anubha Biswas, Saptarshi Goswami   +3 more
doaj   +1 more source

Novel 1,4-substituted-1,2,3-triazoles as antitubercular agents.

, 2015
Tuberculosis (TB) remains a pressing unmet medical need, particularly with the emergence of multidrug-resistant and extensively drug-resistant tuberculosis.
Luke Henderson (13082367), JM Altimari (14466177), A Sajid (13410789), SC Hockey (14527817), HI Boshoff (18718477)   +4 more
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