Results 161 to 170 of about 3,707,085 (259)

Design, synthesis, and biological evaluation of m-amidophenol derivatives as a new class of antitubercular agents. [PDF]

Medchemcomm, 2018
Zhang NN, Liu ZY, Liang J, Tang YX, Qian L, Gao YM, Zhang TY, Yan M.   +7 more
europepmc   +1 more source

Nitrotriazole- and imidazole-based amides and sulfonamides as antitubercular agents. [PDF]

Antimicrob Agents Chemother, 2014
Papadopoulou MV, Bloomer WD, Rosenzweig HS, Arena A, Arrieta F, Rebolledo JC, Smith DK.   +6 more
europepmc   +1 more source

[The hepatotoxicity of antitubercular agents].

Anales de medicina interna (Madrid, Spain : 1984), 1993
J, Alegre Martín, T, Fernández de Sevilla   +1 more
openaire   +1 more source

[Rifampicin: a new antitubercular agent].

Wiadomosci lekarskie (Warsaw, Poland : 1960), 1972
openaire   +1 more source

[Treatment with secondary antitubercular agents].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1968
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Synthesis, biological screening and in silico studies of new N-phenyl-4-(1,3-diaryl-1H-pyrazol-4-yl)thiazol-2-amine derivatives as potential antifungal and antitubercular agents.

European journal of medicinal chemistry, 2023
A new series of N-aryl-4-(1,3-diaryl-1H-pyrazol-4-yl)thiazol-2-amine, (8a-x) have been synthesized by a cyclo-condensation reaction of 2-bromo-1-(1,3-diphenyl-1H-pyrazol-4-yl)ethanone (6a-f) with N-aryl thiourea, (7a-d).
Y. Nandurkar, M. Bhoye, D. Maliwal, R. Pissurlenkar, Abhijit P. Chavan, Sushma R Katade, P. Mhaske   +6 more
semanticscholar   +1 more source

In vitro and in silico exploration of newly synthesized triazolyl- isonicotinohydrazides as potent antitubercular agents

Journal of Biomolecular Structure and Dynamics, 2023
In the present study, we have reported the synthesis of novel isoniazid-triazole derivatives (4a-r), via the click chemistry approach. The synthesized isoniazid-triazole derivatives have potent in vitro antitubercular activity against the Mycobacterium ...
Rajubai D. Bakale, Pramod S. Phatak, Sanket Rathod, Prafulla B. Choudhari, E. M. Rekha, D. Sriram, R. Kulkarni, K. Haval   +7 more
semanticscholar   +1 more source

Discovery of 1,2,3-triazole incorporated indole-piperazines as potent antitubercular agents: Design, synthesis, in vitro biological evaluation, molecular docking and ADME studies.

Bioorganic & Medicinal Chemistry, 2023
In this report, a library consisting of three sets of indole-piperazine derivatives was designed through the molecular hybridization approach. In total, fifty new hybrid compounds (T1-T50) were synthesized and screened for antitubercular activity against
Rajkumar Reddyrajula, Umadevi Etikyala, V. Manga, Udaya Kumar Dalimba   +3 more
semanticscholar   +1 more source

Thiazole Heterocycle: An Incredible and Potential Scaffold in Drug Discovery and Development of Antitubercular Agents

ChemistrySelect, 2023
In 2020, 15 million people were diagnosed with tuberculosis (TB), and 2.4 million died. Additionally, the TB situation is worse with multidrug resistance (MDR) and extended‐drug resistance (XDR)‐TB.
Neeru Bhanwala, V. Gupta, Lokesh Chandrakar, Gopal L. Khatik   +3 more
semanticscholar   +1 more source

Novel linezolid-based oxazolidinones as potent anticandidiasis and antitubercular agents.

Bioorganic chemistry (Print), 2022
The quest for new antifungal and antitubercular drugs is a need of the hour because of morbid co-pathogenesis and an increase in immunocompromised patients.
Shaikh Faazil, M. S. Malik, Saleh A. Ahmed, Reem I Alsantali, P. Yedla, Meshari A Alsharif, I. Shaikh, A. Kamal   +7 more
semanticscholar   +1 more source