Results 11 to 20 of about 506,874 (259)
Antitumor activity of a new antitumor antibiotic, stubomycin.
The Journal of Antibiotics, 1982 The antitumor activity of a new antibiotic, stubomycin, against various murine tumors was studied. Stubomycin showed antitumor activity against Sarcoma 180, IMC-carcinoma and Meth-A tumor. In particular, all of the mice inoculated i.p. with IMC-carcinoma were cured when they were given nine successive injections of stubomycin.
Iwaou Mezawa +3 more
openaire +3 more sources
Influence of Long-term Cytotoxic Chemotherapy on the Condition of Peripheral Venous Channel [PDF]
, 2017 The necessity of long-term venous access in cancer patients appears at frequent and long-term courses of cytotoxic therapy. Peripheral veins of forearms are most often used for these aims. The conditions of peripheral venous channel in 32 cancer patients,
Tkachuk, T. (Tetiana)
core +2 more sources
Antitumor activity of spergualin, a novel antitumor antibiotic.
The Journal of Antibiotics, 1986 Spergualin (SGL), a novel antitumor antibiotic, exhibited strong antitumor activity against transplantable leukemias in mice: L1210, L1210(IMC), P388, P815, C1498, EL-4 and RL male 1. It also exhibited antitumor activity against M5076 fibrosarcoma, AH66 and AH66F rat hepatomas, but not against Meth-A fibrosarcoma, B16 melanoma, Lewis lung carcinoma (LL)
Kiyohiro Nishikawa +5 more
openaire +4 more sources
The Pharmacological Potential of Mushrooms [PDF]
, 2005 This review describes pharmacologically active compounds from mushrooms. Compounds and complex substances with antimicrobial, antiviral, antitumor, antiallergic, immunomodulating, anti-inflammatory, antiatherogenic, hypoglycemic, hepatoprotective and ...
Jülich, Wolf-Dieter +2 more
core +3 more sources
Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]
, 2017 Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana +5 more
core +1 more source
Unusual DNA binding modes for metal anticancer complexes [PDF]
, 2009 DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
core +1 more source
Antitumor effects of somatostatin [PDF]
Molecular and Cellular Endocrinology, 2008 Since its discovery three decades ago as an inhibitor of GH release from the pituitary gland, somatostatin has attracted much attention because of its functional role in the regulation of a wide variety of physiological functions in the brain, pituitary, pancreas, gastrointestinal tract, adrenals, thyroid, kidney and immune system.
Pyronnet, Stéphane +5 more
openaire +4 more sources
A phase I dose-escalation study of TAK-733, an investigational oral MEK inhibitor, in patients with advanced solid tumors. [PDF]
, 2016 Purpose TAK-733, an investigational, selective, allosteric MEK1/2 inhibitor, has demonstrated antitumor effects against multiple cancer cell lines and xenograft models. This first-in-human study investigated TAK-733 in patients with solid tumors. Methods
Adjei, Alex A +11 more
core +1 more source
Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]
, 2016 Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo +42 more
core +1 more source
Tanespimycin as Antitumor Therapy
Clinical Lymphoma Myeloma and Leukemia, 2011 The 90 kDa heat shock protein (HSP90), which facilitates proper folding and stability of numerous signaling molecules involved in growth control, cell survival, and development, has been implicated in malignant processes. Like its parent compound geldanamycin, tanespimycin binds to HSP90 and causes antineoplastic effects in vitro and in vivo.All ...
Dimopoulos, Meletios-Athanassios +3 more
openaire +7 more sources