Results 21 to 30 of about 840,802 (388)

Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]

open access: yes, 2017
Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana   +5 more
core   +1 more source

Anticellular and Antitumor Activity of Duocarmycins, Novel Antitumor Antibiotics [PDF]

open access: yesJapanese Journal of Cancer Research, 1992
The anticellular and antitumor activities of novel antitumor antibiotics, duocarmycins (DUMs), were examined against human and murine tumor cells. DUMs consist of live compounds, A, B1, B2, C1, and C2, which possess a pharmacophore similar to that of CC‐1065, a previously isolated antibiotic.
Gomi, Katsushige   +9 more
openaire   +2 more sources

Transcription factor KLF15 inhibits the proliferation and migration of gastric cancer cells via regulating the TFAP2A-AS1/NISCH axis

open access: yesBiology Direct, 2021
Background Recently, overwhelming evidence supports that long noncoding RNAs (lncRNAs) play crucial roles in the occurrence and progression of tumors. However, the role and mechanism of lncRNA TFAP2A-AS1 in human gastric cancer (GC) remains unclear. Thus,
Xin Zhao   +5 more
doaj   +1 more source

Advances in the design and development of oncolytic measles viruses. [PDF]

open access: yes, 2015
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian   +2 more
core   +1 more source

Disporum nanchuanense (Colchicaceae), a new species from Chongqing, China [PDF]

open access: yesPhytoKeys, 2019
Disporum nanchuanense (Colchicaceae), a new species from Jinfo Mountain National Nature Reserve, Nanchuan District, Chongqing, China, is described and illustrated. It is similar to D. longistylum and D.
Xinxin Zhu, Shuai Liao, Sirong Yi
doaj   +3 more sources

Ganoderma lucidum polysaccharides attenuates pressure-overload-induced pathological cardiac hypertrophy

open access: yesFrontiers in Pharmacology, 2023
Pathological cardiac hypertrophy is an important risk factor for cardiovascular disease. However, drug therapies that can reverse the maladaptive process and restore heart function are limited. Ganoderma lucidum polysaccharides (GLPs) are one of the main
Changlin Zhen   +19 more
doaj   +1 more source

Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]

open access: yes, 2016
Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo   +42 more
core   +1 more source

Hydrophobic cis-platinum complexes efficiently incorporated into liposomes [PDF]

open access: yes, 1992
The present invention involves the synthesis and use of new platinum compounds. These new platinum compounds are easy to encapsulate in liposomes at high efficiencies.
Khokhar, Abdul R.   +2 more
core   +3 more sources

Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity

open access: yesCancer Discovery, 2022
Tumor cells triggered to senesce alter how they send and receive microenvironmental signals, leading to tissue remodeling, immune cell recruitment, hypersensitization to environmental IFNγ, and improved antitumor immunity.
Hsuan-An Chen   +19 more
semanticscholar   +1 more source

Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems [PDF]

open access: yes, 2014
Cervical cancer is the second-most-common cause of malignancies in women worldwide, and the oncogenic activity of the human papilloma virus types (HPV) E7 protein has a crucial role in anogenital tumors.
Atyabi, F.   +8 more
core   +7 more sources

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