Results 41 to 50 of about 17,918 (294)

Detection of Snake Venom in Post-Antivenom Samples by Dissociation Treatment Followed by Enzyme Immunoassay

open access: yesToxins, 2016
Venom detection is crucial for confirmation of envenomation and snake type in snake-bite patients. Enzyme immunoassay (EIA) is used to detect venom, but antivenom in samples prevents venom detection.
Kalana P. Maduwage   +3 more
doaj   +1 more source

Pharmacodynamics and pharmacokinetics of snake antivenom

open access: yesSri Lanka Journal of Medicine, 2018
Intact or fractionated immunoglobulins are used as snake antivenom to treat snake envenomation. Intravenously administered antivenom binds with snake toxins in the circulation and neutralizes the toxins.
Bhagya Nikapitiya, Kalana Maduwage
doaj   +1 more source

Moderate-to-severe Vipera berus envenoming requiring ViperaTAb antivenom therapy in the UK

open access: yesClinical toxicology, 2021
Background Bites by the European adder (Vipera berus) in the UK are uncommon but potentially life threatening, and can be associated with marked limb swelling and disability.
Thomas Lamb   +8 more
semanticscholar   +1 more source

Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
Snake bite is a common medical emergency in Papua New Guinea (PNG). The taipan, Oxyuranus scutellatus, inflicts a large number of bites that, in the absence of antivenom therapy, result in high mortality.
Mariángela Vargas   +12 more
doaj   +1 more source

Analysis of the Necrosis-Inducing Components of the Venom of Naja atra and Assessment of the Neutralization Ability of Freeze-Dried Antivenom

open access: yesToxins, 2021
Patients bitten by Naja atra who are treated with bivalent freeze-dried neurotoxic antivenom in Taiwan have an improved survival rate but develop necrotic wound changes. The World Health Organization (WHO) has suggested using the minimum necrotizing dose
Cheng-Hsuan Ho   +13 more
semanticscholar   +1 more source

An Examination of the Neutralization of In Vitro Toxicity of Chinese Cobra (Naja atra) Venom by Different Antivenoms

open access: yesBiomedicines, 2020
The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N.
Qing Liang   +4 more
doaj   +1 more source

Effect of Several Naja atra Antivenom Injection Methods on the Rabbit Model of Naja naja atra Bite Poisoning

open access: yesJournal of Tropical Medicine, 2023
Snakebite is a global public health concern, which often occurs in tropical and subtropical underdeveloped areas, but it is often neglected. In the southern China, Naja naja atra (Chinese cobra) is a common venomous snake that causes swelling and ...
Jie Yang   +10 more
doaj   +1 more source

Consequences of neglect: analysis of the sub-Saharan African snake antivenom market and the global context. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
BACKGROUND: The worldwide neglect of immunotherapeutic products for the treatment of snakebite has resulted in a critical paucity of effective, safe and affordable therapy in many Third World countries, particularly in Africa.
Nicholas I Brown
doaj   +1 more source

The management of a blood donor bitten by a snake [PDF]

open access: yes, 2017
The worldwide burden of snakebite is high and venomous snakes are found in many regions of the world and are a threat to public health. In Italy, for instance, viper bites are an infrequent but not negligible event.
Catalano, Liviana   +5 more
core   +1 more source

Third Generation Antivenomics: Pushing the Limits of the In Vitro Preclinical Assessment of Antivenoms [PDF]

open access: yesToxins, 2017
Second generation antivenomics is a translational venomics approach designed to complement in vivo preclinical neutralization assays. It provides qualitative and quantitative information on the set of homologous and heterologous venom proteins presenting antivenom-recognized epitopes and those exhibiting impaired immunoreactivity.
Davinia Pla   +2 more
openaire   +6 more sources

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