Results 41 to 50 of about 12,948 (246)
Spider bite: a current approach to management [PDF]
Although spider bite is common, most spider bites cause minor effects and do not require treatment. More significant effects result from redback and, less commonly, from funnel-web spider bites.
Isbister, Geoffrey K.
core +2 more sources
Third Generation Antivenomics: Pushing the Limits of the In Vitro Preclinical Assessment of Antivenoms [PDF]
Second generation antivenomics is a translational venomics approach designed to complement in vivo preclinical neutralization assays. It provides qualitative and quantitative information on the set of homologous and heterologous venom proteins presenting antivenom-recognized epitopes and those exhibiting impaired immunoreactivity.
Davinia Pla+2 more
openaire +6 more sources
Coastal taipan (Oxyuranus scutellatus) envenoming causes life-threatening neuromuscular paralysis in humans. We studied the time period during which antivenom remains effective in preventing and arresting in vitro neuromuscular block caused by taipan ...
Umesha Madhushani+4 more
doaj +1 more source
Snake bite: a current approach to management [PDF]
Snake envenoming is uncommon but potentially life-threatening. It is characterised by systemic effects including coagulopathy, neurotoxicity, myotoxicity and renal impairment.
Isbister, Geoffrey K.
core +1 more source
Recombinant snakebite antivenoms: A cost-competitive solution to a neglected tropical disease? [PDF]
Snakebite envenoming is a major public health burden in tropical parts of the developing world. In sub-Saharan Africa, neglect has led to a scarcity of antivenoms threatening the lives and limbs of snakebite victims.
Andersen, Mikael R+3 more
core +2 more sources
Antivenomics as a tool to improve the neutralizing capacity of the crotalic antivenom: a study with crotamine [PDF]
Snakebite treatment requires administration of an appropriate antivenom that should contain antibodies capable of neutralizing the venom. To achieve this goal, antivenom production must start from a suitable immunization protocol and proper venom mixtures.
Teixeira-Araújo, Ricardo+7 more
openaire +6 more sources
Scorpion envenomation remains a real health problem in many countries. In scorpionism cases, it is often recommended that patients be treated with species-specific antivenom. Androctonus crassicauda venom has been used as antigen for antivenom production
O. Ozkan+5 more
doaj +1 more source
Early Adverse Reactions to Snake Antivenom: Poison Center Data Analysis
Antivenom is an essential treatment for snake envenomation; however, early adverse reactions (EARs) are major limitations to its use. We performed a retrospective cross-sectional study using Ramathibodi Poison Center data (January 2016 to December 2017 ...
Charuwan Sriapha+5 more
doaj +1 more source
A biodistribution study of Hemiscorpius lepturus scorpion venom and available polyclonal antivenom in rats [PDF]
The purpose of the present study was to investigate the biodistribution profile of the venom of Hemiscorpius lepturus, the most dangerous scorpion in Iran.
Babaee, MH+4 more
core +2 more sources
Antivenom availability, delays and use in Australia
Antivenom is the main treatment for snake envenoming and there are ongoing concerns about availability in resource poor regions of the world. However, effective antivenom treatment for snake envenoming requires more than improved availability of safe and
Geoffrey K. Isbister
doaj