Results 11 to 20 of about 3,623,509 (414)
Seven classes of antiviral agents. [PDF]
Cell Mol Life Sci, 2022 AbstractThe viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands are in development. Here, we briefly reviewed 7 classes of antiviral agents: neutralizing antibodies, neutralizing recombinant
Ianevski A +7 more
europepmc +5 more sources
Silver Nanoparticles as Potential Antiviral Agents
Pharmaceutics, 2021 Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which encompasses all spheres of science including chemistry, material science, biology, and biotechnology.
Zubair Ahmed Ratan +9 more
doaj +2 more sources
Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents: A Systematic Review. [PDF]
Antibiotics (Basel), 2023 Bacterial infections have attracted the attention of researchers in recent decades, especially due to the special problems they have faced, such as their increasing diversity and resistance to antibiotic treatment.
Marinescu M.
europepmc +2 more sources
Molecular Mechanisms of Antiviral Agents against Dengue Virus
Viruses, 2023 Dengue is a major global health threat causing 390 million dengue infections and 25,000 deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of a clinically approved antiviral against dengue virus (DENV) drive the ...
Michelle Felicia Lee +2 more
doaj +2 more sources
Broad-spectrum antiviral agents [PDF]
Frontiers in Microbiology, 2015 Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular ...
Jun-Da eZhu +3 more
doaj +3 more sources
Antiviral Agents: Discovery to Resistance [PDF]
Viruses, 2020 In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]
Catherine S. Adamson
doaj +5 more sources
Journal of Thrombosis and Haemostasis, 2020 Antiviral drugs are administered in patients with severe COVID‐19 respiratory syndrome, including those treated with direct oral anticoagulants (DOACs).
Sophie Testa, Gian Battista Danzi
exaly +2 more sources
Modeling long-term longitudinal HIV dynamics with application to an AIDS clinical study [PDF]
Annals of Applied Statistics 2008, Vol. 2, No. 4, 1384-1408, 2009 A virologic marker, the number of HIV RNA copies or viral load, is currently used to evaluate antiretroviral (ARV) therapies in AIDS clinical trials. This marker can be used to assess the ARV potency of therapies, but is easily affected by drug exposures, drug resistance and other factors during the long-term treatment evaluation process.
Huang, Yangxin, Lu, Tao
arxiv +3 more sources
Medicinal chemistry strategies toward host targeting antiviral agents
Medicinal Research Reviews, 2020 Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and have been demonstrated to be very successful in combating viral infections in clinic.
Xingyue Ji, Zhuo-rong Li, Xingyue Ji
exaly +2 more sources
Inhaled Dry Powder of Antiviral Agents: A Promising Approach to Treating Respiratory Viral Pathogens [PDF]
VirusesInhaled dry powder formulations of antiviral agents represent a novel and potentially transformative approach to managing respiratory viral infections. Traditional antiviral therapies in the form of tablets or capsules often face limitations in terms of ...
Tushar Saha +5 more
doaj +2 more sources