Results 11 to 20 of about 3,701,075 (393)
Molecular Mechanisms of Antiviral Agents against Dengue Virus
Viruses, 2023 Dengue is a major global health threat causing 390 million dengue infections and 25,000 deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of a clinically approved antiviral against dengue virus (DENV) drive the ...
Michelle Felicia Lee +2 more
doaj +2 more sources
Discovery and development of safe-in-man broad-spectrum antiviral agents
International Journal of Infectious Diseases, 2020 Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases. However, broad-spectrum antiviral agents (BSAAs, i.e.
Petter I. Andersen +12 more
doaj +2 more sources
Benzothiazoles as potential antiviral agents [PDF]
The Journal of pharmacy and pharmacology, 2020 The recent viral pandemic poses a unique challenge for healthcare providers. Despite the remarkable progress, the number of novel antiviral agents in the pipeline is woefully inadequate against the evolving virulence and drug resistance of current ...
Yahya I. Asiri +4 more
openalex +2 more sources
Isatin derivatives as broad-spectrum antiviral agents: the current landscape [PDF]
Medicinal Chemistry Research, 2022 In recent decades, several viruses have resulted in large outbreaks with serious health, economic and social consequences. The current unprecedented outbreak of the new coronavirus, SARS-COV-2, necessitates intensive efforts for delivering effective ...
Tilal Elsaman +13 more
openalex +2 more sources
Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents: A Systematic Review
Antibiotics, 2023 Bacterial infections have attracted the attention of researchers in recent decades, especially due to the special problems they have faced, such as their increasing diversity and resistance to antibiotic treatment.
M. Marinescu
semanticscholar +1 more source
ACS Applied Materials and Interfaces, 2023 Cationic polysaccharides have demonstrated significant antimicrobial properties and have great potential in medical applications, where the antiviral activity is of great interest. As of today, alcohols and oxidizing agents are commonly used as antiviral
A. Teotia +3 more
semanticscholar +1 more source
Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2
New England Journal of Medicine, 2022 To the Editor: The omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease 2019 (Covid-19), has spread rapidly around the world and has already become the predominant ...
E. Takashita +15 more
semanticscholar +1 more source
Efficacy of Antiviral Agents against Omicron Subvariants BQ.1.1 and XBB
New England Journal of Medicine, 2022 . The cells were incubated for 14–18 h at 37 °C and then fixed with formalin. After the formalin was removed, the cells were immunostained with a mouse monoclonal antibody against SARS-CoV-2 nucleoprotein [N45 (TAUNS Laboratories, Inc ...
M. Imai +12 more
semanticscholar +1 more source
Health Science Reports, 2022 There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on their comparative ...
M. R. Islam +6 more
semanticscholar +1 more source
Synthesis and Applications of Nitrogen-Containing Heterocycles as Antiviral Agents
Molecules, 2022 Viruses have been a long-term source of infectious diseases that can lead to large-scale infections and massive deaths. Especially with the recent highly contagious coronavirus (COVID-19), antiviral drugs were developed nonstop to deal with the emergence
Tuyen N. Tran, M. Henary
semanticscholar +1 more source