Results 21 to 30 of about 3,598,763 (344)
Frontiers in Microbiology, 2022 We report a quantification of the decrease of effectiveness of antiviral agents directed to hepatitis C virus, when the agents are added during an ongoing infection in cell culture vs. when they are added at the beginning of the infection.
Carlos García-Crespo +21 more
doaj +1 more source
PLoS ONE, 2023 BackgroundAcute kidney injury is a complication of COVID-19 and is associated with severity. Despite no specific antiviral treatment strategy, lopinavir/ritonavir and remdesivir have been used.
Seyed Majid Mousavi Movahed +8 more
doaj +1 more source
Antiviral Agents: Discovery to Resistance
Viruses, 2020 In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]
Catherine S. Adamson
doaj +1 more source
Seven classes of antiviral agents
Cellular and Molecular Life Sciences, 2022 The viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands are in development.
A. Ianevski +7 more
semanticscholar +1 more source
Inhibition of SARS Coronavirus Infection In Vitro with Clinically Approved Antiviral Drugs
Emerging Infectious Diseases, 2004 Severe acute respiratory syndrome (SARS) is an infectious disease caused by a newly identified human coronavirus (SARS-CoV). Currently, no effective drug exists to treat SARS-CoV infection.
Emily L.C. Tan +6 more
doaj +1 more source
Comparison of Antiviral Agents for Seasonal Influenza Outcomes in Healthy Adults and Children
JAMA Network Open, 2021 Key Points Question What antiviral agents for treating seasonal influenza are associated with the most safety and best outcomes among healthy adults and children?
Jen-Wei Liu +4 more
semanticscholar +1 more source
Broad-spectrum antiviral agents
Frontiers in Microbiology, 2015 Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular ...
Jun-Da eZhu +3 more
doaj +1 more source
Engineering recombinantly expressed lectin-based antiviral agents
Frontiers in Cellular and Infection Microbiology, 2022 Cyanovirin-N (CV-N), a lectin from Nostoc ellipsosporum was found an infusion inhibitory protein for human immunodeficiency virus (HIV)-1. A tandem-repeat of the engineered domain-swapped dimer bound specific sites at hemagglutinin (HA), Ebola and HIV ...
Irene Maier
doaj +1 more source
Medical Clinics of North America, 1988 Potent effective antiviral drugs recently have been licensed for several viral diseases, ushering in a new era in the treatment of viral diseases. Several unique features in the process of a viral infection have been identified as target points for inhibition. The unique steps and the interfering compounds are the subject of this review.
Reines, Eric D., Gross, Peter A.
openaire +2 more sources
Metal Complexes as Antiviral Agents for SARS‐CoV‐2
ChemBioChem, 2021 The severe acute respiratory syndrome – coronavirus 2 (SARS‐CoV‐2), the infectious agent responsible for COVID‐19 – has caused more than 2.5 million deaths worldwide and triggered a global pandemic. Even with successful vaccines being delivered, there is
J. Karges, Seth M. Cohen
semanticscholar +1 more source