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Chapter 12. Antiviral Agents [PDF]
, 1984 This chapter discusses the agents with activity primarily against RNA viruses. The communicable diseases of the respiratory tract are probably the most common cause of symptomatic human infections. The viruses that are causative agents for human respiratory disease comprise the five taxonomically distinct families: orthomyxoviridae, paramyxoviridae ...
James L. Kelley
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Dermatologic Clinics, 2001 The potential severity of many viral infections and the lack of appropriate treatment for these diseases have been a source of endless frustration and helplessness for clinicians. The newly developed field of antiviral therapy is expanding at an astounding rate, with new discoveries each day.
Shijun Ren +7 more
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Sulfonamides with Heterocyclic Periphery as Antiviral Agents [PDF]
Molecules, 2022 Sulfonamides are the basic motifs for a whole generation of drugs from a large group of antibiotics. Currently, research in the field of the new sulfonamide synthesis has received a “second wind”, due to the increase in the synthetic capabilities of ...
Mikhail Yu. Moskalik
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Frontiers in Pharmacology, 2019 As the leading cause of death worldwide, viruses significantly affect global health. Despite the rapid progress in human healthcare, there are few viricidal and antiviral therapies that are efficient enough.
Pardis Mohammadi Pour +2 more
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Carbazole Derivatives as Antiviral Agents: An Overview
Molecules, 2019 Viruses represent the most common cause of infectious diseases worldwide and those with rapid propagation and high infection rates cause human and animal pandemics. These fast-spreading diseases are generally treated with antiviral drugs but, often, drug
Anna Caruso +7 more
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Breaking the chains: Advancements in antiviral strategies to combat Nipah virus infections [PDF]
International Journal of One Health, 2023 Nipah virus (NiV) is a highly pathogenic zoonotic virus that has caused several outbreaks with high fatality rates in humans and animals, thus, requiring a “One Health” approach. No specific treatment or vaccine is available for NiV infection, making the
Fredmoore L. Orosco
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ACS Applied Materials and Interfaces, 2023 Cationic polysaccharides have demonstrated significant antimicrobial properties and have great potential in medical applications, where the antiviral activity is of great interest. As of today, alcohols and oxidizing agents are commonly used as antiviral
A. Teotia +3 more
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Establishment and application of a high-throughput screening model for cell adhesion inhibitors
Frontiers in Pharmacology, 2023 The cell adhesion between leukocytes and endothelial cells plays an important balanced role in the pathophysiological function, while excessive adhesion caused by etiological agents is associated with the occurrence and development of many acute and ...
Han Sun +18 more
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Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2
New England Journal of Medicine, 2022 To the Editor: The omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible for coronavirus disease 2019 (Covid-19), has spread rapidly around the world and has already become the predominant ...
E. Takashita +15 more
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Efficacy of Antiviral Agents against Omicron Subvariants BQ.1.1 and XBB
New England Journal of Medicine, 2022 . The cells were incubated for 14–18 h at 37 °C and then fixed with formalin. After the formalin was removed, the cells were immunostained with a mouse monoclonal antibody against SARS-CoV-2 nucleoprotein [N45 (TAUNS Laboratories, Inc ...
M. Imai +12 more
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