Results 171 to 180 of about 70,871 (236)

<i>Shallot virus X</i> p42 Protein Expressed in Concert with Virus Movement Proteins Is a Suppressor of Two Plant Antiviral Defense Mechanisms. [PDF]

Plants (Basel)
Chergintsev DA, Lezzhov AA, Lazareva EA, Atabekova AK, Solovieva AD, Morozov SY, Solovyev AG.   +6 more
europepmc   +1 more source

Single‐Cell and Multiomic Analysis Reveals Neutrophil Heterogeneity and Prognostic Value in Cervical Lesions

Cancer Science, EarlyView.
This study is the first to identify a novel neutrophil subpopulation, N4, that is closely associated with the progression of cervical cancer. Characterized by high PLAU expression and specific interactions with tumor cells, N4 neutrophils were shown to promote tumor growth and immune modulation.
Ze Wang, Liang Zhuang, Shiyi Liu, Canhui Cao, Shimin Chen, Nan Yu, Xiaoyuan Huang, Tao Zhang   +7 more
wiley   +1 more source

Characterization and Immune Functions of LcβLectin from Large Yellow Croaker (<i>Larimichthys crocea</i>): A Potential Antiviral Defense Molecule. [PDF]

Int J Mol Sci
Zhang J, Wu H, Huang Y, Yang Y, Yekefenhazi D, Zou W, Han F.   +6 more
europepmc   +1 more source

Influenza A Virus (H1N1) Infection Induces Ferroptosis to Promote Developmental Injury in Fetal Tissues

Cell Proliferation, EarlyView.
H1N1 infection during pregnancy specifically targets the fetal liver and lungs, triggering immune responses, tissue fibrosis and ferroptosis in parenchymal cells, ultimately leading to adverse pregnancy outcomes, offering insights into managing maternal H1N1 infections and their impact on fetal health.
Yuxi Jiang, Yao Shen, Qiongyin Zhang, Zi Liu, Yuzhen Liu, Jiaojiao Peng, Xuesong Yang, Feng Gao, Xiang‐Hong Ou, Qing‐Yuan Sun, Qiao Zhang, Guang Wang   +11 more
wiley   +1 more source

Long-term metagenomic insights into the roles of antiviral defense systems in stabilizing activated sludge bacterial communities. [PDF]

ISME J
Zhang Q, Li J, Tuo J, Liu S, Liu Y, Liu P, Ye L, Zhang XX.   +7 more
europepmc   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

RH3 enhances antiviral defense by facilitating small RNA loading into Argonaute 2 at endoplasmic reticulum-chloroplast membrane contact sites. [PDF]

Nat Commun
Huang J, Du J, Liu Y, Lu L, Xu Y, Shi J, Liu Q, Li Q, Liu Y, Chen Y, Du M, Zhao Y, Huo L, Wang W, Ding C, Wei L, Wu J, Yuan YW, Chen J, Li R, Cui F, Zhang X.   +21 more
europepmc   +1 more source

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Exploring TRIM proteins' role in antiviral defense against influenza A virus and respiratory coronaviruses. [PDF]

Front Cell Infect Microbiol
Wei Y, Song J, Zhang J, Chen S, Yu Z, He L, Chen J.   +6 more
europepmc   +1 more source

Binding of Bacillus subtilis dynamin‐like protein DynA to the bacterial membrane is essential for effective phage defense

The FEBS Journal, EarlyView.
The bacterial dynamin‐like protein DynA from Bacillus subtilis plays a key role in phage defense. It binds the plasma membrane through a unique paddle domain in its D1 subunit. This membrane association is essential for its protective function, likely preventing explosive membrane rupture following phage infection.
Samia Shafqat, Urska Repnik, Marc Bramkamp   +2 more
wiley   +1 more source