The effects of apamin on EtOH were not mediated by an interaction with the GABAergic system.
A, experiments were conducted in presence of bicuculline, which caused the formation of larger and sparse network bursts. The magnitudes of the bursts were reduced by EtOH, and their frequency was increased (summarized in C&D, 6 experiments, 49 cells ...
Tatyana Bombela (485670) +4 more
core +1 more source
Resistance to apamin of the Ca2+-activated K+ permeability in pancreatic B-cells.
The bee venom neurotoxin apamin failed to affect 86Rb outflow and insulin release from rat pancreatic islets stimulated by D-glucose or the Ca2+-ionophore A23187.
Claret, M +9 more
core +1 more source
Fast, But Not Slow, Effects of Olivocochlear Activation Are Resistant to Apamin
Olivocochlear (OC) efferent suppression of auditory-nerve responses comprises a fast effect lasting tens of milliseconds and a slow effect building and decaying over tens of seconds.
M. Charles Liberman +3 more
core +1 more source
Effects of apamin and rapamycin on S6rp phosphorylation in CINs are reproduced in vivo.
(A) Low magnification image of a rat brain section showing the targeted striatal region bilaterally (red cross). Rats received either synaptic blocker solution (blockers; picrotoxin, 150 µM; CNQX disodium, 1 mM; DL-AP5, 1 mM) or the same solution plus ...
Billy C. Chieng (291650) +4 more
core +1 more source
The apamin binding protein was solubilized from rat brain synaptic membranes using sodium cholate. Receptor yield and stability depended closely on the detergent/protein ratio.
F Couraud, B Marqueze, MJ Seagar
core +1 more source
The effect of the ionic composition of bathing solution on the potency of apamin.
Representative recordings of KCa2 current in HEK 293 cells transiently transfected with KCa2.2. The recordings were made in standard solution (A), nominally Ca 2+ and Mg2+ free solution (B) and Na+, Mg2+ and Ca2+ free solution in which NaCl was replaced ...
David Charles Hammond Benton (456734) +2 more
core +1 more source
Charybdotoxin and iberiotoxin but not apamin abolish the slow after-hyperpolarization in myenteric plexus ...
DSH Stephenson (19465888) +4 more
core
Apamin distinguishes two types of relaxation mediated by enteric nerves in the guinea-pig gastrointestinal ...
CMS Humphreys (19465861) +2 more
core
Extended secondhand smoke exposure alters potassium channel activity and reduces excitability of cardiac vagal neurons in mice. [PDF]
Sun J +4 more
europepmc +1 more source
Further Investigations on Natural and Synthetic Bis-(1,2,3,4-tetrahydroisoquinoline) Derivatives Interacting with the Apamin-Sensitive Site of Small-Conductance Calcium-Activated Potassium Channels. [PDF]
Taouba H +8 more
europepmc +1 more source

