Results 81 to 90 of about 5,766 (207)
Journal of Pharmacological Sciences, 2005 A role of ATP in nonadrenergic, noncholinergic (NANC) relaxations was examined in the Wistar rat jejunum. Electrical field stimulation (EFS) induced NANC relaxation of longitudinal muscle of the jejunal segments in a frequency-dependent manner.
Kaori Waseda +6 more
doaj +1 more source
The Journal of Physiology, Volume 603, Issue 20, Page 6269-6284, October 15, 2025.Abstract figure legend KV4 channel availability regulates inferior olive action potential duration. The durations of action potentials in inferior olive neurons (blue) depend strongly on preceding membrane potential, with afterdepolarizations varying over the physiological range by almost two orders of magnitude (open circles). Voltage clamp recordings
Ziyad W. Sultan +2 more
wiley +1 more source
The effect of the ionic composition of bathing solution on the potency of apamin.
, 2013 Representative recordings of KCa2 current in HEK 293 cells transiently transfected with KCa2.2. The recordings were made in standard solution (A), nominally Ca 2+ and Mg2+ free solution (B) and Na+, Mg2+ and Ca2+ free solution in which NaCl was replaced ...
David Charles Hammond Benton (456734) +2 more
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Apamin, a highly potent fetal L-type Ca2+ current blocker in single heart cells
, 1992 Apamin, a bee venom polypeptide, was reported to block the naturally occurring Ca2+ slow action potentials (APs) in cultured cell reaggregates from old chick hearts [Bkaily, G. et al. Am. J. Physiol. 248 (Heart Circ. Physiol.
D. Economos +4 more
core +1 more source
Apamin suppresses the elevated network activity produced by exposure to low EtOH.
, 2013 A, the progress of the experiment; initially the culture was exposed to 0.25% and then to 0.5% EtOH, which produced a sustained rise in network activity. Further, the addition of 40 nM apamin caused a return to baseline network activity.
Tatyana Bombela (485670) +4 more
core +1 more source
Cell-Cycle-Dependent Regulation of Ca2+-Activated K+ Channel in Jurkat T-Lymphocyte
Journal of Pharmacological Sciences, 2007 Small-conductance Ca2+-activated K+ (SK2) channel plays an important role in the activation of Jurkat T-lymphocytes by maintaining electrical gradients for the sustained Ca2+ influx. Apamin-sensitive K+ current was significantly decreased with cell-cycle
Takashi Morimoto +4 more
doaj +1 more source
Effect of apamin on ISK2 in transfected HEK 293 cells.
, 2014 (A) The representative ISK2 tracings obtained by the descending voltage ramp protocol shown in the inset before (a) and after (b) apamin at time points indicated by arrows a and b in (B). (B) The time course of ISK2 at 0 mV.
Chih-Chieh Yu (127641) +3 more
core +1 more source
Activity-Dependent Plasticity of Spike Pauses in Cerebellar Purkinje Cells
Cell Reports, 2016 The plasticity of intrinsic excitability has been described in several types of neurons, but the significance of non-synaptic mechanisms in brain plasticity and learning remains elusive. Cerebellar Purkinje cells are inhibitory neurons that spontaneously
Giorgio Grasselli +5 more
doaj +1 more source
International Journal of Electrochemical Science, 2015 We present in this manuscript for the first time the electrochemical and statistical evaluation of FPLC isolation of mellitin and apamin from honey bee (Apis mellifera) venom. Venoms are extremely complex blends of diverse substances that target a myriad
Hoai Viet Nguyen +10 more
doaj +1 more source
Increase of apamin receptors in skeletal muscle induced by colchicine: possible role in myotonia
, 1992 We have shown an increase of apamin receptors in rat skeletal muscle membranes following the application of colchicine to the sciatic nerve. 125I-apamin binding to partially purified membrane fractions was observed since day 4, reached a maximum around ...
M. I. Behrens, C. Vergara
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