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Effects of Apelin-13 on Auditory System in STZ-Induced Diabetic Rats
Neuroscience LettersDamage to the auditory pathways is one of the complications of diabetes. The aim of this study was to investigate the potential therapeutic effects of apelin-13 in the auditory pathways of rats with experimentally induced diabetes by examining its effect on auditory brainstem responses, cochlear oxidative stress and inflammatory cytokines.Thirty-two ...
Sevtap, Kılınç +4 more
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Intracerebroventricular administration of apelin-13 inhibits distal colonic transit in mice
Peptides, 2010Apelin is a novel bioactive peptide as the endogenous ligand for the orphan G-protein-coupled receptor (GPCR), APJ, a receptor distributed in various tissues such as the hypothalamus and the gastrointestinal tract. Recent reports showed that apelin regulated many biological functions, including blood pressure, neuroendocrine, drinking behavior and food
Yan-Jie, Yang +4 more
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Impact of Apelin-13 on the Development of Coronary Artery Ectasia.
Acta Cardiologica SinicaCoronary artery ectasia (CAE) is the limitation or diffuse expansion of the epicardial coronary artery. In most cases, the pathological basis of CAE is considered to be coronary atherosclerosis. Previous studies have confirmed the association between Apelin and arterial atherosclerosis.
Xusen, Sun +3 more
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Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility
Circulation Research, 2002István Szokodi +2 more
exaly
Molecular properties of apelin: tissue distribution and receptor binding
Biochimica Et Biophysica Acta - Molecular Cell Research, 2001Naoki Nishizawa +2 more
exaly
Vascular effects of apelin: Mechanisms and therapeutic potential
Pharmacology & Therapeutics, 2018Amreen Mughal
exaly