Results 31 to 40 of about 7,079 (169)
The Study of Apelin-13 for the Assessment of Endothelial Dysfunction in Prehypertension and Hypertension Patients [PDF]
International Journal of Scientific Research in Dental and Medical Sciences, 2023 Background and aim: Hypertension is a leading global burden of deaths, coronary heart diseases, and stroke. Hypertension causes low-grade chronic systemic inflammation associated with endothelial dysfunction and vascular complications.
Balu Kanumuru +3 more
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Apelin and its Receptor: An Overview [PDF]
Journal of Clinical and Diagnostic Research, 2019 Apelin protein is an endogenous ligand of Apelin Receptor (APJ). APJ is a member of G-protein coupled receptor family. Both apelin and its receptor express extensively in the human body.
Rajeev Gandham +4 more
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Frontiers in Pharmacology, 2022 The incidence of cerebral ischemia has increased in the past decades, and the high fatality and disability rates seriously affect human health. Apelin is a bioactive peptide and the ligand of the G protein-coupled receptor APJ.
Jiabin Li +3 more
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The adipokine apelin-13 induces expression of prothrombotic tissue factor [PDF]
Thrombosis and Haemostasis, 2015 Adipocytes are cells able to produce and secrete several active substances (adipokines) with direct effects on vascular cells. Apelin, one of the most recently identified adipokines has been studied in cardiovascular system physiology in regard to vessel vasodilation and myocardial contraction, but it has not yet completely characterised for its ...
CIRILLO, PLINIO +9 more
openaire +7 more sources
ASN Neuro, 2015 Apelin is a peptide originally isolated from bovine stomach tissue extracts and identified as an endogenous ligand of the APJ receptor; recent work showed that apelin ameliorates the ischemic injury in the heart and the brain.
Dongdong Chen +4 more
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Apelin-13 inhibits apoptosis and excessive autophagy in cerebral ischemia/reperfusion injury
Neural Regeneration Research, 2021 Apelin-13 is a novel endogenous ligand for an angiotensin-like orphan G-protein coupled receptor, and it may be neuroprotective against cerebral ischemia injury. However, the precise mechanisms of the effects of apelin-13 remain to be elucidated.
Zi-Qi Shao +6 more
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Evaluation of Serum Apelin-13 in Psoriasis Vulgaris Patients [PDF]
Benha Journal of Applied Sciences, 2020 Psoriasis is a chronic, T-cell mediated inflammatory skin disease with multifactorial etiology. Recent studies support the relation of psoriasis with obesity. Apelin-13 is a novel adipokine that is secreted from white adipose tissue and plays a role in T-cell immunity.
S.M. Abdalhady +3 more
openaire +1 more source
Changes of apelin-13 concentration in patients with essential hypertension and extrasystole
Arterial Hypertension, 2022 BACKGROUND: Hypertension is one of the leading causes of disability and mortality among cardiovascular diseases, so today new metabolic markers of cardiovascular risk are being actively studied. One of them is apelin-13.
Anastasiia Ivankova +3 more
doaj +1 more source
Effect of 12 Weeks of Endurance Training on Plasma Levels of Apelin-13, Insulin, and Glucose in Obese Male Rats [PDF]
Ṭibb-i Tavānbakhshī, 2021 Background and Aims: Apelin is a newly discovered adipokine whose level is high in obese people with insulin resistance. It is not clear how endurance training affects apelin plasma levels.
zahra Rostami Hashjin +2 more
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Neural Regeneration Research, 2015 Apelin-13 inhibits neuronal apoptosis caused by hydrogen peroxide, yet apoptosis following cerebral ischemia-reperfusion injury has rarely been studied. In this study, Apelin-13 (0.1 µg/g) was injected into the lateral ventricle of middle cerebral artery
Xiao-ge Yan +6 more
doaj +1 more source