Results 101 to 110 of about 15,683 (226)
Mediators of Inflammation, Volume 2026, Issue 1, 2026.Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao +5 more
wiley +1 more source
The Role of Apelin in the Functioning of the Reproductive System
Acta Biomedica Scientifica, 2019 Adipokine apelin through the apelin receptors activates a wide range of signaling cascades in the target cells and controls their growth, differentiation, apoptosis, and energy metabolism.
A. O. Shpakov, K. V. Derkach
doaj +1 more source
High Phosphate Load Induces De Novo Formation of Tertiary Lymphoid Structures in the Kidney
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.Graphical illustration of renal alterations under varying phosphate load: High phosphate load induces fibrosis, tubular injury, impaired renal function, and de novo formation of perivascular tertiary lymphoid structures. Under normal phosphate load, fibrosis, functional decline, and tubular injury are absent, while T‐ and B‐ cell aggregates are present
Nina Weingärtner +8 more
wiley +1 more source
Maternal Exercise Rescues Fetal Akinesia‐Impaired Joint and Bone Development
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.Spontaneous fetal movements exert mechanical forces that shape the developing skeleton. Clinically, conditions that impair fetal movements (i.e., fetal akinesia) can cause defects in skeletal development. The Splotch‐delayed (Spd) mouse model, which features limited skeletal muscle development, recapitulates this fetal akinesia phenotype. We found that
Christopher J. Panebianco +9 more
wiley +1 more source
Cannabidiol (CBD) modulation of apelin in acute respiratory distress syndrome [PDF]
, 2020 Évila Lopes Salles +9 more
openalex +1 more source
Frontiers in Endocrinology, 2018 Apelin receptor(s) (APLNR) are suggested to mediate the actions of apelin and Elabela (ELA) peptides in many physiological processes, including cardiovascular development and food intake in vertebrates.
Jiannan Zhang +10 more
doaj +1 more source
The apelin-13 peptide protects the heart against apoptosis through the ERK/MAPK and PI3K/AKT signaling pathways. [PDF]
, 2020 Xuejun Wang +6 more
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Mìžnarodnij Endokrinologìčnij Žurnal, 2014 The physiological and pathogenetic role of adipokine apelin, endogenous ligand of apelin (APJ or APLNR) receptors in the development of glucose metabolism disorders has been analyzed.
G.V. Demidenko
doaj +1 more source
Myocardial impact and cardioprotective effects of apelin-13 and a c-terminal-modified analog during lps and clp experimental sepsis [PDF]
, 2015 Olivier Lesur
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