Results 11 to 20 of about 10,376 (262)

The Differentiation Potential of Apical Papilla Cells in Relation to Tenascin-C and Syndecan-1 Expression and Their Potential Role in Regeneration [PDF]

International Journal of Dentistry
Conclusions: Cell differentiation potential in the developing swine apex is progressively restricted to the newly formed dental pulp, whereas phenotypic expression of apical papilla cells remains undetermined unless the new microenvironment triggers cell
K. Kodonas, A. Fardi, S. Papadimitriou, C. Gogos   +3 more
doaj   +3 more sources

Histatin-1 promotes the expression of markers associated with odontoblastic differentiation in the dental pulp and apical papilla [PDF]

Scientific Reports
Complex tooth injuries, including dental caries, require the reestablishment of tissue architecture and functionality through the regeneration of cellular populations that enable tertiary dentin formation and the reestablishment of vascular and neural ...
Patricio Silva, Mauricio Garrido, Héctor A. Tapia, Diego Ormeño, Sebastián Benito, Jorge Segura, Floris J. Bikker, Kamran Nazmi, Elías Utreras, Mónica Cáceres, Vicente A. Torres   +10 more
doaj   +3 more sources

Differential expression of Notch related genes in dental pulp stem cells and stem cells isolated from apical papilla [PDF]

Journal of Oral Biology and Craniofacial Research, 2021
Although dental pulp and apical papilla are originated from neural crest cells, these tissues exhibit distinct characteristics. Notch signaling is one of the known signaling pathways regulating stemness and behaviors of stem cells.
Damrong Damrongsri, Nunthawan Nowwarote, Opor Sonpoung, Suphalak Photichailert, Thanaphum Osathanon   +4 more
doaj   +2 more sources

N-Acetylcysteine Protects the Stem Cells of the Apical Papilla

Frontiers in Dental Medicine, 2022
ObjectivePrevious research has demonstrated that stem cells of the apical papilla (SCAP) have a lower differentiation potential and are less resistant to cell death as compared to other stem cells. N-acetyl cysteine (NAC) prevents apoptosis of the dental
Kyle Countryman, Yen-Wei Chen, James D. Johnson, Avina Paranjpe   +3 more
doaj   +2 more sources

Cellular response of human apical papilla cells to calcium hydroxide and tricalcium silicate-based cements [PDF]

BMC Oral Health, 2021
Background This study aimed to evaluate the biological response of human apical papilla cells to different calcium hydroxide formulations and three tricalcium silicate-based materials.
Mauricio Garrido, Diego Morales, María Paz Saldías, Christian Fernández, Veronica Villalobos, Oscar Cerda, Mónica Cáceres   +6 more
doaj   +2 more sources

Effects of a New Bioceramic Material on Human Apical Papilla Cells [PDF]

Journal of Functional Biomaterials, 2018
Background: The development of materials with bioregenerative properties is critically important for vital pulp therapies and regenerative endodontic procedures.
Diana B. Sequeira, Catarina M. Seabra, Paulo J. Palma, Ana Luísa Cardoso, João Peça, João Miguel Santos   +5 more
doaj   +4 more sources

Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer [PDF]

Frontiers in Cell and Developmental Biology, 2023
Stem cells from the apical papilla (SCAPs) are promising candidates for regenerative endodontic treatment and tissue regeneration in general. However, harvesting enough cells from the limited apical papilla tissue is difficult, and the cells lose their ...
Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Chang Liu, Chang Liu, Chang Liu, Chang Liu, Qiuman Chen, Wenping Luo, Tong-Chuan He, Deqin Yang, Deqin Yang, Deqin Yang, Deqin Yang   +14 more
doaj   +3 more sources

Different concentrations of fetal bovine serum affect cytokine modulation in Lipopolysaccharide-activated apical papilla cells in vitro [PDF]

Journal of Applied Oral Science, 2023
Fetal bovine serum (FBS) is the most used supplement in culture media; however, it may interfere with in vitro assays via effects on cell proliferation and cytokine production.
Letícia Martins SANTOS, Patricia e Silva CARDOSO, Elisa Abreu DINIZ, Juliana Garuba RAHHAL, Carla Renata SIPERT   +4 more
doaj   +2 more sources

Effects of ethylenediaminetetraacetic acid on stem cells from the apical papilla: In vitro study [PDF]

Journal of Dental Sciences, 2023
Ethylenediaminetetraacetic acid (EDTA) is used as an irrigant in regenerative endodontic treatment. The present study aimed to investigate the effects of EDTA on stem cells from apical papilla (SCAPs) in vitro.Human SCAPs were isolated and characterised. The cells were treated with media supplemented with EDTA at concentrations ranging from 1.25% to 17%
Suphalak Phothichailert, Benya Sangwisutsai, Dhitinant Rattanakosol, Nutcha Teerapongpaibul, Sirawut Hiran-us, Nunthawan Nowwarote, Thanaphum Osathanon   +6 more
openaire   +6 more sources

Wnt-directed CXCL12-expressing apical papilla progenitor cells drive tooth root formation [PDF]

Nature Communications
The tooth root is a critical component of the tooth anchored to surrounding alveolar bones. Tooth root formation is driven by cells in the apical papilla (AP) that generate new dentin-forming odontoblasts at the root-forming front. Mesenchymal stem cells
Mizuki Nagata, Gaurav T. Gadhvi, Taishi Komori, Yuki Arai, Hiroaki Manabe, Angel Ka Yan Chu, Ramandeep Kaur, Meer Ali, Yuntao Yang, Chiaki Tsutsumi-Arai, Yuta Nakai, Yuki Matsushita, Nicha Tokavanich, W. Jim Zheng, Joshua D. Welch, Noriaki Ono, Wanida Ono   +16 more
doaj   +2 more sources