Results 11 to 20 of about 195,126 (269)
Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla [PDF]
BMC Oral HealthBackground Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. The present study aimed to explore the effect of simvastatin on the osteogenic differentiation of Stem Cells isolated from Apical Papilla ...
Paak Rewthamrongsris +6 more
doaj +5 more sources
WIF1 enhanced dentinogenic differentiation in stem cells from apical papilla
BMC Oral Health, 2019 Background Odontogenic mesenchymal stem cells (MSCs) isolated from tooth tissues are a reliable resource that can be utilized for dental tissue regeneration.
Haifeng Wang, Yu Cao
doaj +4 more sources
Bioactivity effects of extracellular matrix proteins on apical papilla cells [PDF]
Journal of Applied Oral Science, 2021 Potent signaling agents stimulate and guide pulp tissue regeneration, especially in endodontic treatment of teeth with incomplete root formation. Objective This study evaluated the bioactive properties of low concentrations of extracellular matrix ...
Maria Luísa LEITE +6 more
doaj +8 more sources
Journal of Oral Biology and Craniofacial Research, 2021 Although dental pulp and apical papilla are originated from neural crest cells, these tissues exhibit distinct characteristics. Notch signaling is one of the known signaling pathways regulating stemness and behaviors of stem cells.
Damrong Damrongsri +4 more
doaj +2 more sources
Dental Apical Papilla as Therapy for Spinal Cord Injury
Journal of Dental Research, 2015 Stem cells of the apical papilla (SCAP) represent great promise regarding treatment of neural tissue damage, such as spinal cord injury (SCI). They derive from the neural crest, express numerous neurogenic markers, and mediate neurite outgrowth and ...
Deumens, Ronald +15 more
core +3 more sources
N-Acetylcysteine Protects the Stem Cells of the Apical Papilla
Frontiers in Dental Medicine, 2022 ObjectivePrevious research has demonstrated that stem cells of the apical papilla (SCAP) have a lower differentiation potential and are less resistant to cell death as compared to other stem cells. N-acetyl cysteine (NAC) prevents apoptosis of the dental
Kyle Countryman +3 more
doaj +2 more sources
Cellular response of human apical papilla cells to calcium hydroxide and tricalcium silicate-based cements [PDF]
BMC Oral Health, 2021 Background This study aimed to evaluate the biological response of human apical papilla cells to different calcium hydroxide formulations and three tricalcium silicate-based materials.
Mauricio Garrido +6 more
doaj +2 more sources
Dental pulp and apical papilla cells senescence : causes, consequences, and prevention
Biogerontology, 2023 Dental pulp under physiological condi tions has a defense function, repair capacity, and important mechanisms in pathological processes. In addition, the dental papilla is involved in important defense processes and an essential function in the pulp ...
Rezende, Taia Maria Berto +1 more
core +4 more sources
Effects of a New Bioceramic Material on Human Apical Papilla Cells [PDF]
Journal of Functional Biomaterials, 2018 Background: The development of materials with bioregenerative properties is critically important for vital pulp therapies and regenerative endodontic procedures.
Diana B. Sequeira +5 more
doaj +4 more sources
Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer [PDF]
Frontiers in Cell and Developmental Biology, 2023 Stem cells from the apical papilla (SCAPs) are promising candidates for regenerative endodontic treatment and tissue regeneration in general. However, harvesting enough cells from the limited apical papilla tissue is difficult, and the cells lose their ...
Qianyu Cheng +14 more
doaj +2 more sources