Results 111 to 120 of about 51,943 (224)

Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao, Yuan Zong, Tao Wang, Jianan Li, Zengrong Ye, Famei Zhang, Guoying Zhou   +6 more
wiley   +1 more source

Advances in Eco‐Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions

Analytical Science Advances, Volume 7, Issue 1, June 2026.
Fruit bioactive compounds offer antioxidant, anti‐inflammatory, and preventive benefits, yet extraction is hindered by poor solubility and conventional methods using toxic solvents and high energy. This review evaluates traditional and advanced eco‐friendly technologies, highlighting efficiency, selectivity, and sustainability.
Abadi Gebreyesus Hndeya, Desta Berhe Sbhatu, Gebreselema Gebreyohannes   +2 more
wiley   +1 more source

Mechanistic insights into EIF6 as a target of Apigenin in alleviating chondrocyte senescence

Experimental Gerontology
Purpose: Apigenin, a flavonoid found in edible plants, has demonstrated therapeutic potential in various diseases, but its role in knee osteoarthritis (KOA) remains unclear. This study aimed to identify the potential targets and mechanisms of Apigenin in
Erliang Li, Hui Yu, Xin Xu, Min Wang, Mingyi Yang, Zhi Yang, Peng Xu   +6 more
doaj   +1 more source

Preliminary qualitative screening for cancer chemopreventive agents in Telfairia occidentalis Hook.f., Gnetum africanum Welw., Gongronema latifolium Benth. and Ocimum gratissimum L. from Nigeria [PDF]

, 2009
The leaves of four plant foods commonly consumed in Nigeria namely Gnetum africanum (Igbo name: Ukazi), Gongronema latifolium (Igbo name: Utazi), Telfairia occidentalis (Igbo name: Ugu), Ocimum gratissimum (Igbo name: Nchoanwu), were each screened for ...
Iweala, E. E. J.
core  

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs [PDF]

, 2019
We endeavored to identify objective blood biomarkers for pain, a subjective sensation with a biological basis, using a stepwise discovery, prioritization, validation, and testing in independent cohorts design. We studied psychiatric patients, a high risk
Jones, T., Judd, S., Khan, F., Kurian, S. M., Le-Niculescu, H., Levey, D. F., McCormick, M.A., Niculescu, A. B., Rogers, J., Roseberry, K., Soe, K. C., Wessel, A. R., White, F. A., Williams, A.   +13 more
core   +2 more sources

Apigenin decreases expression of the myofibroblast phenotype

FEBS Letters, 2001
We investigated the effect of the dietary flavonoid apigenin on myofibroblast function. We report that in myofibroblasts treated with apigenin, proliferation and basal levels of α1(I) collagen and α‐smooth muscle actin mRNAs were markedly reduced. Apigenin also attenuated the transforming growth factor‐β‐stimulated increases of α1(I) collagen and α ...
Ricupero, Dennis A, Poliks, Christine F, Rishikof, David C, Kuang, Ping-Ping, Goldstein, Ronald H   +4 more
openaire   +2 more sources

Electrospun Gelatin/OSA‐Starch Nanofibers for Encapsulation and Controlled Release of Sage Extract

Journal of Applied Polymer Science, Volume 143, Issue 15, April 15, 2026.
Schematic representation of electrospun gelatin/OSA‐starch nanofibers encapsulating sage extract, illustrating fabrication, nanofiber formation, and sustained antioxidant release. ABSTRACT In recent years, increasing research efforts have focused on assessing the potential of polymeric nanofibers to improve the bioavailability and stability of active ...
Rozhin Mohagheghian, Akram Pezeshki, Babak Ghanbarzadeh, Maryam Mohammadi, M. Ali Aboudzadeh   +4 more
wiley   +1 more source

Activation of PPARγ by a Natural Flavonoid Modulator, Apigenin Ameliorates Obesity-Related Inflammation Via Regulation of Macrophage Polarization

EBioMedicine, 2016
PPARγ has emerged as a master regulator of macrophage polarization and is the molecular target of the thiazolidinedione drugs. Here we show that apigenin binds and activates PPARγ by acting as a modulator.
Xiujing Feng, Dan Weng, Feifei Zhou, Young D. Owen, Haohan Qin, Jingfa Zhao, WenYu, Yahong Huang, Jiajia Chen, Haijian Fu, Nanfei Yang, Dianhua Chen, Jianxin Li, Renxiang Tan, Pingping Shen   +14 more
doaj   +1 more source

Antioxidant activity of thyme waste extract in O/W emulsions [PDF]

, 2019
Thymus vulgaris (thyme) is an aromatic plant and its essential oil has been applied as antimicrobial and antioxidant due to the presence of phenolic compounds.
AAZZA, Smail, Anahi Dandlen, Susana, Antunes, Maria Dulce, EL-GEUNDOUZ, Soukaina, Gomes, Vera, Lyoussi, Badiaa, MAJDOUB, Nesrine, Miguel, Maria, Raposo, Sara   +8 more
core   +1 more source

Identification of Quality Markers in Viola kunawaresis Royel Using HPLC Fingerprints, Chemometric Analysis, and Network Pharmacology

Biomedical Chromatography, Volume 40, Issue 4, April 2026.
ABSTRACT Violae tianshanicae herba (VTH), a widely used crude drug in Uyghur medicine in China, is renowned for its immunomodulatory, anti‐inflammatory, antibacterial, antiviral, and antidiabetic activities, with notable efficacy in treating asthma. However, systematic research on its quality markers (Q‐markers) remains limited, underscoring the need ...
Haifeng Liu, Rongmei Zhao, Hong Xu, Tabusi Manaer, Le Pan, Lu Jin, Amatjan Ayupbek   +6 more
wiley   +1 more source