Correction to an immunometabolism-related signature for renal clear cell carcinoma diagnosis and therapeutic target. [PDF]
J Cell Commun SignalJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
europepmc +2 more sources
An immunometabolism-related signature for renal clear cell carcinoma diagnosis and therapeutic target. [PDF]
J Cell Commun SignalAbstract Kidney renal clear cell carcinoma (KIRC) lacks sensitive biomarkers for early diagnosis and effective guidance for personalized therapy. Given the close interplay between tumor metabolism and immune regulation, this study aimed to identify immunometabolism‐related biomarkers for KIRC and develop a robust diagnostic model.
Hu G, Liang J, Feng M, Lin H, He J.
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Variability in HIV-1 transmitted/founder virus susceptibility to combined APOBEC3F and APOBEC3G host restriction. [PDF]
J VirolSeveral APOBEC3 enzymes restrict HIV-1 by deaminating cytosine to form uracil in single-stranded proviral (−)DNA. However, HIV-1 Vif counteracts their activity by inducing their proteasomal degradation.
Gaba A +3 more
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Engineered Transformer Base Editor with Enhanced Editing Efficiency. [PDF]
Adv Sci (Weinh)A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Chen B +5 more
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Molecules, 2022 The apolipoprotein B mRNA editing enzyme catalytic subunit 3G (APOBEC3G) converts cytosine to uracil in DNA/RNA. Its role in resisting viral invasion has been well documented.
Chenchen Ma +6 more
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Effects of APOBEC3G on the replications of severe fever with thrombocytopenia syndrome virus
Zhongguo shuxue zazhi, 2023 Objective To study the effect of apolipoprotein B mRNA editing enzyme catalytic subunit 3G (APOBEC3G)on virus replication and IL-6 production during severe fever with thrombocytopenia syndrome virus (SFTSV) infection.
Yanixn TAO +5 more
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Model structure of human APOBEC3G. [PDF]
PLoS ONE, 2007 APOBEC3G (apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G) has antiretroviral activity associated with the hypermutation of viral DNA through cytosine deamination.
Kun-Lin Zhang +6 more
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Retroviral restriction factor APOBEC3G delays the initiation of DNA synthesis by HIV-1 reverse transcriptase. [PDF]
PLoS ONE, 2013 It is well established that the cytosine deaminase APOBEC3G can restrict HIV-1 virions in the absence of the virion infectivity factor (Vif) by inducing genome mutagenesis through deamination of cytosine to uracil in single-stranded HIV-1 (-)DNA. However,
Madison B Adolph +2 more
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APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host. [PDF]
PLoS Pathogens, 2013 Cellular restriction factors, which render cells intrinsically resistant to viruses, potentially impose genetic barriers to cross-species transmission and emergence of viral pathogens in nature. One such factor is APOBEC3G.
Annabel Krupp +6 more
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Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity. [PDF]
PLoS Pathogens, 2009 The cytidine deaminases APOBEC3G and APOBEC3F exert anti-HIV-1 activity that is countered by the HIV-1 vif protein. Based on potential transcription factor binding sites in their putative promoters, we hypothesized that expression of APOBEC3G and ...
Michael L Vetter +4 more
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