Strategies for Metabolic Engineering of Escherichia coli for β-Carotene Biosynthesis [PDF]
β-Carotene has extensive applications in the food, pharmaceutical, and cosmetics industries. Traditional chemical synthesis methods face challenges such as byproduct residues and high costs, whereas natural extraction is constrained by low yields and ...
Jiali Liu +6 more
doaj +2 more sources
Bioconversion of carotenoids into high-value crocins using a marine sponge carotenoid cleavage dioxygenase. [PDF]
Summary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Moreno-Giménez E +11 more
europepmc +2 more sources
Beyond pigments and perfumes: engineering in the carotenoid and apocarotenoid spectrum, novel enzymes, and synthetic biology strategies [PDF]
Carotenoids and apocarotenoids constitute a structurally and functionally sundry class of isoprenoids whose significance extends from photosynthetic light capture and photoprotection to phytohormone signaling, flavor and aroma formation, and emerging ...
Baradwaj Ravi Gopal, Zhen Q. Wang
doaj +2 more sources
An evolutionarily diverged CCD4 enzyme negatively regulates mesocotyl elongation in rice. [PDF]
New Phytologist, Volume 249, Issue 4, Page 1569-1579, February 2026.
Zhang Y +10 more
europepmc +2 more sources
Occurrence and Chemical Synthesis of Apocarotenoids from Mucorales: A Review
Apocarotenoids are metabolites originated by degradation of carotenes through the loss of carbon atoms placed at the side chain of their structure as consequence of oxydative reactions.
Alejandro F Barrero +2 more
exaly +2 more sources
Carotenoids and apocarotenoids are diverse classes of compounds found in nature and are important natural pigments, nutraceuticals and flavour/aroma molecules. Improving the quality of crops is important for providing micronutrients to remote communities
Andrew J Simkin, Simkin Andrew J
exaly +3 more sources
Co-regulatory network analysis of the main secondary metabolite (SM) biosynthesis in Crocus sativus L. [PDF]
Saffron (Crocus sativus L.) is being embraced as the most important medicinal plant and the commercial source of saffron spice. Despite the beneficial economic and medicinal properties of saffron, the regulatory mechanism of the correlation of TFs and ...
Mahsa Eshaghi, Sajad Rashidi-Monfared
doaj +2 more sources
Enrique Cerdá-Olmedo: An Outstanding Scientist and Mentor. [PDF]
Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Avalos J, Corrochano LM.
europepmc +2 more sources
Elucidation of the interaction of apocarotenoids with calf thymus DNA by biophysical techniques and in vitro study in MCF-7 cells to explore their potential in cancer therapy [PDF]
Objective(s): DNA is one of the targets of cancer-therapeutic small molecules. Cisplatin, a DNA intercalator, is one of the first-line drugs in the cancer chemo regimen which comes with health-compromising side effects during chemotherapy.
Jill Mathew, Siva Ramamoorthy
doaj +1 more source
Fortification and bioaccessibility of saffron apocarotenoids in potato tubers
Carotenoids are C40 isoprenoids with well-established roles in photosynthesis, pollination, photoprotection, and hormone biosynthesis. The enzymatic or ROS-induced cleavage of carotenoids generates a group of compounds named apocarotenoids, with an ...
Lourdes Gómez Gómez +20 more
doaj +1 more source

