Research progress on the pharmacological activity, biosynthetic pathways, and biosynthesis of crocins [PDF]
Beilstein Journal of Organic ChemistryCrocins are water-soluble apocarotenoids isolated from the flowers of crocus and gardenia. They exhibit various pharmacological effects, including neuroprotection, anti-inflammatory properties, hepatorenal protection, and anticancer activity.
Zhongwei Hua, Nan Liu, Xiaohui Yan
exaly +3 more sources
Development of a UHPLC-MS method to avoid the in-source dissociation interference in characterization of crocins from Buddlejae flos and its dyeing yellow rice [PDF]
Frontiers in Plant ScienceBuddlejae flos, the flower bud of Buddleja officinalis Maxim., has been used in traditional Chinese medicine to promote eye health and as a yellow food dye for cooking rice in China. Crocins are a class of essential pharmacological ingredients and edible
Si Cheng +19 more
doaj +2 more sources
Natural CCD2 Variants and RNA Interference for Boosting Crocin Biosynthesis in Tomato [PDF]
BiologyCrocin biosynthesis involves a complex network of enzymes with biosynthetic and modifier enzymes, and the manipulation of these pathways holds promise for improving human health through the broad exploitation of these bioactive metabolites.
Elena Moreno-Giménez +9 more
doaj +2 more sources
Montbretia flowers as a source of bioactive crocins: Biotechnology tools and delivery systems [PDF]
Biotechnology ReportsCrocins are potent antioxidants with significant therapeutic potential, exhibiting anti-inflammatory, anticancer, and antidepressant properties. The ornamental plant Crocos-mia x crocosmiiflora is widely cultivated for its aromatic and vibrant flowers ...
Lucía Morote +12 more
doaj +2 more sources
Efficient purification of CrocinI from saffron stigmas using antisolvent precipitation to implications for food technology [PDF]
Scientific ReportsMajor bioactive compounds, crocin compounds, the major bio-actives of saffron, exhibit significant antioxidant, anti-inflammatory, and anticancer properties.
Elmira Fotouhi +3 more
doaj +2 more sources
Production of Saffron Apocarotenoids in Nicotiana benthamiana Plants Genome-Edited to Accumulate Zeaxanthin Precursor [PDF]
Metabolites, 2023 Crocins are glycosylated apocarotenoids with strong coloring power and anti-oxidant, anticancer, and neuro-protective properties. We previously dissected the saffron crocin biosynthesis pathway, and demonstrated that the CsCCD2 enzyme, catalyzing the ...
Olivia Costantina Demurtas +7 more
doaj +2 more sources
Optimizing a tomato crocin biofactory by fine-tuning plant architecture [PDF]
Frontiers in Plant ScienceTomato (Solanum lycopersicum) has emerged as a promising platform for the sustainable production of high-value metabolites. In this study, we demonstrate that plant architecture remodeling via genome editing can be exploited as a chassis optimization ...
Maria Lobato-Gómez +3 more
doaj +2 more sources
Biotechnological production of crocetin and crocins using a carotenoid cleavage dioxygenase (CCD4) from Nyctanthes arbor-tristis [PDF]
Frontiers in Plant ScienceCrocins are hydrophilic crocetin esters composed of a linear chain with glucose molecules added at the end. Crocins and crocetin are used as cosmetic agents and effective pharmaceuticals for the treatment of several diseases.
Lucía Morote +11 more
doaj +2 more sources
Fractionation of Saffron (Crocus sativus L.) Extract by Solid-Phase Extraction and Subsequent Encapsulation in Liposomes Prepared by Reverse-Phase Evaporation [PDF]
MoleculesSaffron (Crocus sativus L.) is one of the most valued spices worldwide, rich in bioactive apocarotenoids such as crocins, picrocrocin, and safranal, which display antioxidant, neuroprotective, and anticancer properties.
Fabrizio Ruggieri +4 more
doaj +2 more sources
Influence of Solvent Polarity on Crocin Content and Surface Properties of Saffron (Crocus sativus L.) Extracts [PDF]
MoleculesThe saffron composition is being widely studied for authenticity and traceability, but very few works have been carried out to investigate the relationship between the chemical and physico-chemical properties of saffron solutes and their technological ...
Rachele Rocchi +4 more
doaj +2 more sources