Saffron as a Retinal Neuroprotectant: A Narrative Review of Preclinical Studies and Clinical Results [PDF]
AntioxidantsThe present narrative review reports the main preclinical and clinical results obtained by using supplementation of saffron or its pure components in neurodegeneration, with special emphasis on age-related macular degeneration.
Maria Anna Maggi +7 more
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Distribution of Main Bioactive Compounds from Saffron Species as a Function of Infusion Temperature and Time in an Oil/Water System [PDF]
MoleculesMost research on saffron has focused on its composition and beneficial effects, while the culinary perspective to enhance its gastronomic potential remains unexplored.
Inmaculada Criado-Navarro +3 more
doaj +2 more sources
A Combined Gas and Liquid Chromatographic Approach for Quality Evaluation of Saffron-Based Food Supplements [PDF]
Foods, 2023 Considering the interest in the bioactive properties of saffron (Crocus sativus L.), as well as its limited production and high price, saffron-based food supplements (SFS) are highly susceptible to adulteration. However, their complex composition and the
Adal Mena-García +3 more
doaj +2 more sources
Transcriptome analysis in tissue sectors with contrasting crocins accumulation provides novel insights into apocarotenoid biosynthesis and regulation during chromoplast biogenesis [PDF]
Scientific Reports, 2018 Crocins, the red soluble apocarotenoids of saffron, accumulate in the flowers of Crocus species in a developmental and tissue-specific manner. In Crocus sieberi, crocins accumulate in stigmas but also in a distinct yellow tepal sector, which we ...
Oussama Ahrazem +10 more
doaj +5 more sources
Crocins Ameliorate Experimental Immune Checkpoint Inhibitor-Related Myocarditis by Targeting the Hpx/Nrf2/HO-1 Pathway. [PDF]
Int J Mol SciImmune checkpoint inhibitors (ICIs) for cancer therapy may induce immune-related adverse events including myocarditis, which occurs infrequently but carries a high mortality rate.
Yan J +6 more
europepmc +2 more sources
High-Purity Preparation of Enzyme Transformed Trans-Crocetin Reclaimed from Gardenia Fruit Waste
Plants, 2022 The recovery of physiologically bioactive ingredients from agricultural wastes as an abundant and low-cost source for the production of high value-added mutraceuticlas has been recognized and supported for the commercial interests and sustainable ...
Charng-Cherng Chyau +6 more
doaj +1 more source
The Biosynthesis of Non-Endogenous Apocarotenoids in Transgenic Nicotiana glauca
Metabolites, 2022 Crocins are high-value compounds with industrial and food applications. Saffron is currently the main source of these soluble pigments, but its high market price hinders its use by sectors, such as pharmaceutics.
Xin Huang +6 more
doaj +1 more source
Prospects and progress on crocin biosynthetic pathway and metabolic engineering
Computational and Structural Biotechnology Journal, 2020 Crocins are a group of highly valuable apocarotenoid-derived pigments mainly produced in Crocus sativus stigmas and Gardenia jasminoides fruits, which display great pharmacological activities for human health, such as anticancer, reducing the risk of ...
Taoli Liu +6 more
doaj +1 more source
Anti-Depressant Properties of Crocin Molecules in Saffron
Molecules, 2022 Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with therapeutic effects. It has been described in pharmacopoeias to be variously acting, including as an anti-depressant, anti-carcinogen, and stimulant agent.
Shahida Anusha Siddiqui +6 more
doaj +1 more source
Metabolic Engineering of Crocin Biosynthesis in Nicotiana Species
Frontiers in Plant Science, 2022 Crocins are high-value soluble pigments that are used as colorants and supplements, their presence in nature is extremely limited and, consequently, the high cost of these metabolites hinders their use by other sectors, such as the pharmaceutical and ...
Oussama Ahrazem +8 more
doaj +1 more source