Saffron as a Retinal Neuroprotectant: A Narrative Review of Preclinical Studies and Clinical Results [PDF]
AntioxidantsThe present narrative review reports the main preclinical and clinical results obtained by using supplementation of saffron or its pure components in neurodegeneration, with special emphasis on age-related macular degeneration.
Maria Anna Maggi +7 more
doaj +2 more sources
Distribution of Main Bioactive Compounds from Saffron Species as a Function of Infusion Temperature and Time in an Oil/Water System [PDF]
MoleculesMost research on saffron has focused on its composition and beneficial effects, while the culinary perspective to enhance its gastronomic potential remains unexplored.
Inmaculada Criado-Navarro +3 more
doaj +2 more sources
Neuroprotective properties of exosomes and chitosan nanoparticles of Tomafran, a bioengineered tomato enriched in crocins [PDF]
Natural Products and BioprospectingSaffron has many pharmacological properties in addition to being a frequently used food seasoning. Crocin and picrocrocin which accumulate in saffron stigma, are responsible for these pharmacological properties.
Mikel Etxebeste-Mitxeltorena +6 more
doaj +2 more sources
A Combined Gas and Liquid Chromatographic Approach for Quality Evaluation of Saffron-Based Food Supplements [PDF]
Foods, 2023 Considering the interest in the bioactive properties of saffron (Crocus sativus L.), as well as its limited production and high price, saffron-based food supplements (SFS) are highly susceptible to adulteration. However, their complex composition and the
Adal Mena-García +3 more
doaj +2 more sources
Bioconversion of carotenoids into high-value crocins using a marine sponge carotenoid cleavage dioxygenase. [PDF]
New PhytolSummary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Moreno-Giménez E +11 more
europepmc +2 more sources
High-Purity Preparation of Enzyme Transformed Trans-Crocetin Reclaimed from Gardenia Fruit Waste
Plants, 2022 The recovery of physiologically bioactive ingredients from agricultural wastes as an abundant and low-cost source for the production of high value-added mutraceuticlas has been recognized and supported for the commercial interests and sustainable ...
Charng-Cherng Chyau +6 more
doaj +1 more source
The Biosynthesis of Non-Endogenous Apocarotenoids in Transgenic Nicotiana glauca
Metabolites, 2022 Crocins are high-value compounds with industrial and food applications. Saffron is currently the main source of these soluble pigments, but its high market price hinders its use by sectors, such as pharmaceutics.
Xin Huang +6 more
doaj +1 more source
Molecules, 2021 Consistent experimental evidence suggests that anesthetic doses of the non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist ketamine cause severe memory impairments in rodents.
Nikolaos Pitsikas, Petros A. Tarantilis
doaj +1 more source
Crocins from Crocus sativus L. in the Management of Hyperglycemia. In Vivo Evidence from Zebrafish
Molecules, 2020 Diabetes mellitus is a disease characterized by persistent high blood glucose levels and accompanied by impaired metabolic pathways. In this study, we used zebrafish to investigate the effect of crocins isolated from Crocus sativus L., on the control of ...
Eleni Kakouri +4 more
doaj +1 more source
Molecules, 2021 Crocins are highly valuable natural compounds for treating human disorders, and they are also high-end spices and colorants in the food industry. Due to the limitation of obtaining this type of highly polar compound, the commercial prices of crocins I ...
Shuguang Guan +9 more
doaj +1 more source