Results 11 to 20 of about 993 (143)

Neuroprotective properties of exosomes and chitosan nanoparticles of Tomafran, a bioengineered tomato enriched in crocins [PDF]

open access: yesNatural Products and Bioprospecting
Saffron has many pharmacological properties in addition to being a frequently used food seasoning. Crocin and picrocrocin which accumulate in saffron stigma, are responsible for these pharmacological properties.
Mikel Etxebeste-Mitxeltorena   +6 more
doaj   +3 more sources

Crocins from Crocus sativus L. in the Management of Hyperglycemia. In Vivo Evidence from Zebrafish

open access: yesMolecules, 2020
Diabetes mellitus is a disease characterized by persistent high blood glucose levels and accompanied by impaired metabolic pathways. In this study, we used zebrafish to investigate the effect of crocins isolated from Crocus sativus L., on the control of ...
Eleni Kakouri   +4 more
doaj   +2 more sources

Homogenate Extraction of Crocins from Saffron Optimized by Response Surface Methodology [PDF]

open access: yesJournal of Chemistry, 2018
Saffron, which has many kinds of biological activities, has been widely used in medicine, cosmetics, food, and other fields of health promotion industries. Crocins are the main component of saffron (Crocus sativus L.).
Yingpeng Tong   +7 more
doaj   +3 more sources

Crocins with high levels of sugar conjugation contribute to the yellow colours of early-spring flowering crocus tepals. [PDF]

open access: yesPLoS ONE, 2013
Crocus sativus is the source of saffron spice, the processed stigma which accumulates glucosylated apocarotenoids known as crocins. Crocins are found in the stigmas of other Crocuses, determining the colourations observed from pale yellow to dark red. By
Angela Rubio Moraga   +4 more
doaj   +3 more sources

Crocins, the Bioactive Components of Crocus sativus L., Counteract the Disrupting Effects of Anesthetic Ketamine on Memory in Rats

open access: yesMolecules, 2021
Consistent experimental evidence suggests that anesthetic doses of the non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist ketamine cause severe memory impairments in rodents.
Nikolaos Pitsikas, Petros A. Tarantilis
doaj   +2 more sources

Structural characterization of highly glucosylated crocins and regulation of their biosynthesis during flower development in Crocus [PDF]

open access: yesFrontiers in Plant Science, 2015
Crocin biosynthesis in Crocus has been proposed to proceed through a zeaxanthin cleavage pathway catalyzed by carotenoid cleavage dioxygenase 2 (CCD2), and followed by glucosylation reactions catalyzed by CsGT2 (UGT74AD1).
OUSSAMA eAHRAZEM   +3 more
doaj   +3 more sources

Optimization of a Solid-Phase Extraction Procedure for the Separation of Picrocrocin and Crocins from Saffron Extract

open access: yesCompounds, 2023
Saffron is a spice derived from the flower of Crocus sativus used as a flavoring and coloring agent in the food industry which also possesses medicinal properties.
Panagiota-Kyriaki Revelou   +8 more
doaj   +3 more sources

Scale-Up Preparation of Crocins I and II from Gardeniajasminoides by a Two-Step Chromatographic Approach and Their Inhibitory Activity Against ATP Citrate Lyase

open access: yesMolecules, 2021
Crocins are highly valuable natural compounds for treating human disorders, and they are also high-end spices and colorants in the food industry. Due to the limitation of obtaining this type of highly polar compound, the commercial prices of crocins I ...
Shuguang Guan   +9 more
doaj   +2 more sources

Effective Isolation of Picrocrocin and Crocins from Saffron: From HPTLC to Working Standard Obtaining

open access: yesMolecules, 2022
Saffron is widely cultivated and used as a spice. Recently published data on the chemical composition and pharmacological potential of saffron determine its use in pharmacy and medicine.
Laurynas Jarukas   +5 more
doaj   +2 more sources

The GABAA-Benzodiazepine Receptor Antagonist Flumazenil Abolishes the Anxiolytic Effects of the Active Constituents of Crocus sativus L. Crocins in Rats

open access: yesMolecules, 2020
Anxiety is a chronic severe psychiatric disorder. Crocins are among the various bioactive components of the plant Crocus sativus L. (Iridaceae) and their implication in anxiety is well-documented.
Nikolaos Pitsikas, Petros A. Tarantilis
doaj   +2 more sources

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