Results 41 to 50 of about 178,943 (330)

Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery [PDF]

, 2007
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial ...
Baker, Andrew H., Brewer, James M., Garside, Paul, Ialenti, Armando, Kennedy, Simon, Maffia, Pasquale, McInnes, Iain B., Zinselmeyer, Bernd H.   +7 more
core   +1 more source

C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro [PDF]

, 2015
Subjects carrying the T2238C ANP gene variant have a higher risk to suffer a stroke or myocardial infarction. The mechanisms through which T2238C/αANP exerts detrimental vascular effects need to be fully clarified.
Bianchi, Franca, Cotugno, Maria, DI CASTRO, SARA, FRATI, GIACOMO, MARCHITTI, Simona, RUBATTU, Speranza Donatella, SCARPINO, Stefania, SCIARRETTA, SEBASTIANO, Stanzione, Rosita, VOLPE, Massimo   +9 more
core   +1 more source

The age-related paraoxonase 1 response is altered by long-term caloric restriction in male and female rats

Journal of Lipid Research, 2006
Caloric restriction (CR) has been shown to attenuate age-related oxidative damage and to improve major atherosclerotic risk factors. Paraoxonase 1 (PON1), an enzyme specifically associated with HDL containing apolipoproteins A-I and J, has been reported ...
Elena Thomàs-Moyà, Magdalena Gianotti, Ana M. Proenza, Isabel Lladó   +3 more
doaj   +1 more source

Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]

, 2014
Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce, Huang, Jincui, Lebrilla, Carlito B, Lee, Hyeyoung, Rivera, Nancy, Smilowitz, Jennifer T, Zivkovic, Angela M   +6 more
core   +1 more source

Effect of urotensin II on apolipoprotein B 100 and apolipoprotein A-I expression in HepG2 cell line

Advanced Biomedical Research, 2014
Background: Increased apolipoprotein B100 (apo B) and decreased apolipoprotein A-I (apo A-I) production are important risk factors in atherosclerosis.
Abbas Mohammadi, Ahmad Gholamhoseinian Najar, Amirhosein Khoshi   +2 more
doaj   +1 more source

Probable Early-Onset Alzheimer's Disease in an Apolipoprotein E2 Homozygote [PDF]

, 2010
Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) epsilon 2/epsilon 2 homozygote. Background: Apo epsilon 2/epsilon 2 is the rarest of the ApoE genotypes, representing only 1.4% of the population.
Belden, Christine, Berk, Camryn, Cole, Lauren, Jacobson, Sandra, Liebsack, Carolyn, Myers, Kent, Reninger, Cornelia, Sabbagh, Marwan N.   +7 more
core   +2 more sources

Characterization of four lipoprotein classes in human cerebrospinal fluid

Journal of Lipid Research, 2001
Lipoprotein metabolism in brain has not yet been fully elucidated, although there are a few reports concerning lipids in the brain and lipoproteins and apolipoproteins in the cerebrospinal fluid (CSF).
Stefanie Koch, Nicolette Donarski, Kathrin Goetze, Miriam Kreckel, Hans-Joerg Stuerenburg, Carsten Buhmann, Ulrike Beisiegel   +6 more
doaj   +1 more source

Efficacy and Safety of High-Density Lipoprotein/Apolipoprotein A1 Replacement Therapy in Humans and Mice With Atherosclerosis: A Systematic Review and Meta-Analysis

Frontiers in Cardiovascular Medicine, 2021
Background: Although elevation of HDL-C levels by pharmaceutical drugs have no benefit of cardiovascular endpoint, the effect of high-density lipoprotein/apolipoprotein A1 (HDL/apoA-1) replacement therapy on atherosclerosis is controversial.
Ayiguli Abudukeremu, Canxia Huang, Hongwei Li, Runlu Sun, Runlu Sun, Xiao Liu, Xiao Liu, Xiaoying Wu, Xiaoying Wu, Xiangkun Xie, Xiangkun Xie, Jingjing Huang, Jingjing Huang, Jie Zhang, Jie Zhang, Jinlan Bao, Yuling Zhang, Yuling Zhang   +17 more
doaj   +1 more source

Enhancing Wound Healing and Anti-Inflammatory Effects by Combination of CIGB-258 and Apolipoprotein A-I against Carboxymethyllysine Toxicity in Zebrafish: Insights into Structural Stabilization and Antioxidant Properties. [PDF]

Antioxidants (Basel)
Cho KH, Lee Y, Lee SH, Kim JE, Bahuguna A, Dominguez-Horta MDC, Martinez-Donato G.   +6 more
europepmc   +3 more sources

Apolipoprotein E and Atherosclerosis: From Lipoprotein Metabolism to MicroRNA Control of Inflammation. [PDF]

, 2018
Apolipoprotein (apo) E stands out among plasma apolipoproteins through its unprecedented ability to protect against atherosclerosis. Although best recognized for its ability to mediate plasma lipoprotein clearance in the liver and protect against ...
Hasty, Hui, Hussain, Lin, Mahley, Pepe, Roselaar   +6 more
core   +2 more sources