Results 51 to 60 of about 92,863 (145)

Importance of Apolipoprotein A-I in Multiple Sclerosis [PDF]

Frontiers in Pharmacology, 2015
Jean-Martin Charcot has first described multiple sclerosis (MS) as a disease of the central nervous system (CNS) over a century ago. MS remains incurable today, and treatment options are limited to disease modifying drugs. Over the years, significant advances in understanding disease pathology have been made in autoimmune and neurodegenerative ...
Lidia A Gardner, Lidia A Gardner, Michael C Levin, Michael C Levin, Michael C Levin   +4 more
openaire   +5 more sources

Anti-inflammatory apoA-I-mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I*

Journal of Lipid Research, 2008
4F is an anti-inflammatory, apolipoprotein A-I (apoA-I)-mimetic peptide that is active in vivo at nanomolar concentrations in the presence of a large molar excess of apoA-I.
Brian J. Van Lenten, Alan C. Wagner, Chun-Ling Jung, Piotr Ruchala, Alan J. Waring, Robert I. Lehrer, Andrew D. Watson, Susan Hama, Mohamad Navab, G.M. Anantharamaiah, Alan M. Fogelman   +10 more
doaj   +1 more source

Protein heterogeneity of lipoprotein particles containing apolipoprotein A-I without apolipoprotein A-II and apolipoprotein A-I with apolipoprotein A-II isolated from human plasma.

Journal of Lipid Research, 1988
The protein heterogeneity of fractions isolated by immunoaffinity chromatography on anti-apolipoprotein A-I and anti-apolipoprotein A-II affinity columns was analyzed by high resolution two-dimensional gel electrophoresis.
R W James, D Hochstrasser, J D Tissot, M Funk, R Appel, F Barja, C Pellegrini, A F Muller, D Pometta   +8 more
doaj   +1 more source

Reevaluation of the role of the multidrug-resistant P-glycoprotein in cellular cholesterol homeostasis

Journal of Lipid Research, 2006
The multidrug resistance P-glycoprotein (P-gp) was recently proposed to redistribute cholesterol in the plasma membrane, suggesting that P-gp could modulate cholesterol efflux to cholesterol acceptors.
Wilfried Le Goff, Megan Settle, Diane J. Greene, Richard E. Morton, Jonathan D. Smith   +4 more
doaj   +1 more source

Apolipoprotein E is secreted by cultured lipocytes of the rat liver.

Journal of Lipid Research, 1991
Hepatic lipocytes, the retinoid-storing cells of the liver, share several characteristics with vascular smooth muscle cells. To determine whether they also share the characteristic of apolipoprotein E secretion, we have compared the relative mRNA ...
G Friedman, LM Liu, SL Friedman, JK Boyles   +3 more
doaj   +1 more source

A comparison of two methods to investigate the metabolism of human apolipoproteins A-I and and A-II.

Journal of Lipid Research, 1978
Two methods are compared for measuring the kinetic parameters of apolipoprotein A-I and A-II metabolism in human plasma. In the first, high density lipoprotein apoproteins were radioiodinated in situ in the lipoprotein particle (endogenous apoprotein ...
J Shepherd, C J Packard, A M Gotto, Jr, O D Taunton   +3 more
doaj   +1 more source

Correlation between the level of cholesteryl ester transfer protein in follicular fluid with fertilization rates in IVF/ ICSI cycles [PDF]

Iranian Journal of Reproductive Medicine, 2011
Background: Follicular fluid (FF) plays an important role in oocytes and embryo development, which may contribute to IVF/ICSI success rate. Objective: The aim of this study was to investigate the correlation between cholesteryl ester transfer protein ...
Amir Mehdizadeh, Ali Rahimipour, Laya Farzadi, Masoud Darabi, Amir-Mansour Vatankhah, Zahra Golmohamadi, Mohammad Nouri   +6 more
doaj  

Diagnostic and Severity Assessment of Coronary Artery Disease Using ApoB/ApoA-I Ratio: Insights from a Statin-Treated Eastern European Cohort

Medicina
Background and Objectives: Atherosclerosis continues to be a major determinant of the global health burden, with ischemic heart disease representing one of the leading causes of morbidity and mortality worldwide.
Raul-Alexandru Jigoranu, Ovidiu Mitu, Alexandru Florinel Oancea, Radu-Stefan Miftode, Ana Maria Buburuz, Amin Bazyani, Radu-Sebastian Gavril, Theodor-Constantin Stamate, Cristina Andreea Adam, Ionela-Larisa Miftode, Antoniu Octavian Petris, Irina-Iuliana Costache Enache, Florin Mitu   +12 more
doaj   +1 more source

Association of polymorphisms in apolipoprotein A-I gene with plasma lipid profile in population of Saint-Petersburg

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014
Apolipoprotein A-I is a key structure protein of antiatherogenic high density lipoproteins (HDL). The aim of the study was to investigate the relationship between (-75)G/A and 83C/T polymorphic variants of apolipoprotein A-I gene (APOA1) and the plasma ...
V. V. Miroshnikova, A. A. Panteleeva, S. N. Pchelina, A. L. Schwarzman   +3 more
doaj   +1 more source

Serum Apolipoprotein A-I Combined With C-Reactive Protein Serves As A Novel Prognostic Stratification System For Colorectal Cancer

Cancer Management and Research, 2019
Juan Ye,1–3,* Qiu-yun Luo,1,* Xue-ping Wang,4 Zhen-yi Liu,5 Mei-xian Chen,6 Hao Huang,7 Lin Zhang1,4 1Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-
Ye J, Luo Q, Wang X, Liu Z, Chen M, Huang H, Zhang L   +6 more
doaj