Results 231 to 240 of about 45,443 (285)

Associations of obesity, systemic inflammation, and hyperinsulinemia with the incidence of non‐communicable chronic disease and mortality: A prospective cohort study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obesity, systemic inflammation, and hyperinsulinemia are all features of metabolic syndrome and frequently occur together. We aimed to evaluate the association of body mass index (BMI) with incident non‐communicable chronic disease (NCD) or all‐cause mortality, independent of C‐reactive protein (CRP) and fasting insulin.
Natasha Wiebe, Stephanie Thompson, Peter Stenvinkel, Aminu Bello, Matthew T. James, Marcello Tonelli   +5 more
wiley   +1 more source

Insight into the metabolic shifts in Graves' hyperthyroidism: a study of acylcarnitine and lipid profiles. [PDF]

Eur Thyroid J
Neset MT, Ulvik A, Løvås K, Laupsa-Borge J, Breivik LE, Stokland AM, Nedrebø BG, Rødahl E, Husebye E, Ueland GÅ, Ueland HO.   +10 more
europepmc   +1 more source

Extracellular vesicle proteomics identifies novel blood biomarkers for the early diagnosis of status epilepticus

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina, Laura Abraira, Daniel Campos‐Fernández, Manuel Quintana, Elena Fonseca, Samuel López‐Maza, Sofía Lallana, Anna Penalba, Anna Rosell, Júlia Valor‐Blanquer, Clara Sanz, Manuel Toledo   +11 more
wiley   +1 more source

Exchangeable APOA1 on HDL inhibits LDL binding to proteoglycans. [PDF]

J Lipid Res
Geh EN, Swertfeger DK, Roscoe I, Street SE, Bursey A, Sexmith H, Woollett LA, Davidson WS, Shah AS.   +8 more
europepmc   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source

High-density lipoprotein: a biomarker and therapeutic target in sepsis. [PDF]

Crit Care
Li M, Barros-Pinkelnig M, Arbous SM, Christoffersen C, Rensen PCN, Kooijman S.   +5 more
europepmc   +1 more source

Alcohol consumption and risk of dementia: a systematic review and meta‐analysis

Internal Medicine Journal, EarlyView.
Abstract To examine the relationship between alcohol intake and the risk of developing dementia, we conducted a comprehensive search of PubMed, Embase, Cochrane Library and Web of Science databases for relevant studies up to July 22, 2024. The quality of the original studies was appraised utilising the Newcastle‐Ottawa Scale (NOS).
Ren Zhang, Baitao Li, Yue Miao
wiley   +1 more source

Changes After Leptin Administration in Partial Lipodystrophy and Factors Associated With Hepatic and Metabolic Response. [PDF]

J Endocr Soc
Akinci B, Ajluni N, Meral R, Neidert AH, Freitas MF, Gilio D, Conjeevaram H, Oral EA.   +7 more
europepmc   +1 more source

APOE ε4 and Decline in Health and Financial Literacy in Advanced Age

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Health and financial literacy decline in aging, but it is unclear why. In this study, we hypothesized that older people who are carriers of the APOE ε4 allele exhibit a steeper decline in literacy over time. Methods Participants were 851 community‐dwelling older adults without dementia at analytic baseline (188 ε4 carriers and 663 ...
Christopher C. Stewart, Lei Yu, Alifiya Kapasi, David A. Bennett, Patricia A. Boyle   +4 more
wiley   +1 more source

Impact of a 12-week High-Intensity Interval Training With Spirulina Supplementation on Insulin Resistance-Mediated by Apo-A, -B, and -J in Men With Obesity HIIT With Spirulina on Apolipoproteins. [PDF]

Eur J Sport Sci
Tayebi SM, Bagherian P, Bassami M, Basereh A, Ahmadabadi S.   +4 more
europepmc   +1 more source