Results 281 to 290 of about 76,034 (338)

Chicken Oocytes and Fibroblasts Express Different Apolipoproteins-B-Specific Receptors

, 1989
Kôzô Hayashi, Johannes Nimpf, Wolfgang J. Schneider   +2 more
openalex   +1 more source

Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu, Kyungdo Kim, Nicholas Asiimwe, Chan Hyun Na   +3 more
wiley   +1 more source

The Impact of Cannabidiol (CBD) on Lipid Absorption and Lymphatic Transport in Rats. [PDF]

Nutrients
Zhu Q, Yang Q, Shen L, Xu M, Liu M.
europepmc   +1 more source

Population Pharmacokinetics and Exposure‐Response Modeling for Evinacumab in Children, Adolescents, and Adults With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 (ANGPTL3) inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C), independent of low‐density lipoprotein receptor, in patients with homozygous familial hypercholesterolemia (HoFH). A population pharmacokinetic (PK)/pharmacodynamic (PD) model was previously developed to characterize ...
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Yuhuan Wang, Poulabi Banerjee, Robert Pordy, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +8 more
wiley   +1 more source

Low apolipoprotein A-II levels causally contribute to increased mortality in septic shock. [PDF]

J Intensive Care
Takahashi N, Campbell KR, Shimada T, Nakada TA, Russell JA, Walley KR.   +5 more
europepmc   +1 more source

Serum lipid and apolipoprotein profiles after onset of acute myocardial infarction.

, 1984
Junichi Sasaki, Tomoki Kawano, Yasushi Sasaki, Yasuyuki Ishihara, Teizo Sata, Kikuo Arakawa   +5 more
openalex   +2 more sources

Comparison of Model‐Predicted and Observed Evinacumab Pharmacokinetics and Efficacy in Children Aged < 5 Years With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C) in patients with homozygous familial hypercholesterolemia (HoFH). Herein, we report pharmacokinetic and efficacy analyses of evinacumab in < 5‐year‐old patients with HoFH.
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Katy C. Norman, Richard T. George, Xue‐Qiao Zhao, Robert Pordy, Daniel Garcia, Wendy S. Putnam, Geetha Raghuveer, Brian W. McCrindle, Elena Fornari, Ivo Baric, Shubha Srinivasan, Melissa Diamond, Eliot A. Brinton, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +18 more
wiley   +1 more source

Deciphering Acute Coronary Syndromes Pathobiology Through Proteomics. [PDF]

J Cardiovasc Dev Dis
Nieddu G, Formato M, Lepedda AJ.
europepmc   +1 more source

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell, Amin Rostami‐Hodjegan, Guy Meno‐Tetang, Donald E. Mager, Kayode Ogungbenro   +4 more
wiley   +1 more source

Study of Hard Protein Corona on Lipid Surface of Composite Nanoconstruction. [PDF]

Nanomaterials (Basel)
Epanchintseva AV, Baranova SV, Poletaeva JE, Bakhno IA, Ryabchikova EI, Dovydenko IS.   +5 more
europepmc   +1 more source