Results 121 to 130 of about 43,955 (304)

Effects of a dietary intervention with lacto-ovo-vegetarian and Mediterranean diets on apolipoproteins and inflammatory cytokines: results from the CARDIVEG study

Nutrition & Metabolism
Background Apolipoproteins have been recently proposed as novel markers of cardiovascular disease (CVD) risk. However, evidence regarding effects of diet on apolipoproteins is limited.
Giuditta Pagliai, Marta Tristan Asensi, Monica Dinu, Francesca Cesari, Alessia Bertelli, Anna Maria Gori, Betti Giusti, Rossella Marcucci, Francesco Sofi, Barbara Colombini   +9 more
doaj   +1 more source

Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. [PDF]

, 2017
In the 50 years since acute respiratory distress syndrome (ARDS) was first described, substantial progress has been made in identifying the risk factors for and the pathogenic contributors to the syndrome and in characterising the protein expression ...
Calfee, Carolyn S, Meyer, Nuala J
core   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake

Disease Models & Mechanisms, 2015
Improved understanding of lipoproteins, particles that transport lipids throughout the circulation, is vital to developing new treatments for the dyslipidemias associated with metabolic syndrome.
Jessica P. Otis, Erin M. Zeituni, James H. Thierer, Jennifer L. Anderson, Alexandria C. Brown, Erica D. Boehm, Derek M. Cerchione, Alexis M. Ceasrine, Inbal Avraham-Davidi, Hanoch Tempelhof, Karina Yaniv, Steven A. Farber   +11 more
doaj   +1 more source

Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. [PDF]

, 2019
BACKGROUND: The relevance of blood lipid concentrations to long-term incidence of cardiovascular disease and the relevance of lipid-lowering therapy for cardiovascular disease outcomes is unclear.
Alver, M. (Maris), Amouyel, P. (Philippe), Bakker, S.J.L. (Stephan), Benjamin, E.J. (Emelia J.), Blankenberg, S. (Stefan), Bobak, M. (Martin), Brambilla, P. (Paolo), Brenner, H. (Hermann), Brunner, F.J. (Fabian J), Costanzo, S. (Simona), Dallongeville, J., de Lemos, J.A. (James A), Dobson, A. (Annette), Donfrancesco, C. (Chiara), Drygas, W. (Wojciech), Dullaart, R.P.F. (Robin P.F.), Dörr, M. (Marcus), Eliasson, M. (Mats), Engström, G., Ferrières, J. (Jean), Giampaoli, S. (Simona), Gianfagna, F. (Francesco), Giles, G. (Graham), Grassi, G. (Guido), Hodge, A. (Allison), Hveem, K. (Kristian), Iacoviello, L. (Licia), Ikram, M.K. (M. Kamran), Ingelsson, M. (Martin), Jorgensen, T. (Torben), Jousilahti, P. (Pekka), Jääskeläinen, T. (Tuija), JöCkel, K.-H. (Karl-Heinz), Kavousi, M. (Maryam), Kee, F. (F.), Klotsche, J. (Jens), Koenig, W. (Wolfgang), Kontto, J. (Jukka), Kuulasmaa, K. (Kari), Lackner, K.J. (Karl), Landmesser, U. (Ulf), Leistner, D.M. (David M), Linneberg, A. (Allan), Lorenz, T. (Thiess), Lyngbakken, M.N. (Magnus N.), Magliano, D.J., Makarova, N. (Nataliya), Malyutina, S., Mathiesen, E.B. (Ellisiv), Meisinger, C. (Christa), Melander, O. (Olle), Metspalu, A. (Andres), Moitry, M. (Marie), Männistö, S. (Satu), Nauck, M. (Matthias), Niiranen, T. (Teemu), Nikitin, Y., Ojeda, F. (Francisco), Omland, T. (Torbjørn), Pajak, A. (Andrzej), Panagiotakos, D.B. (Demosthenes), Peters, A. (Annette), Pitsavos, C. (Christos), Riserus, U. (Ulf), Salomaa, V. (Veikko), Sans, S. (Susana), Schmidt, B. (Börge), Schöttker, B. (Ben), Shaw, J.E., Shea, S. (Steven), Signorini, S. (Stefano), Simons, L.A. (Leon), Söderberg, S. (Stefan), Tamosiunas, A. (Abdonas), Thorand, B. (Barbara), Tunstall-Pedoe, H. (Hugh), Twerenbold, R. (Raphael), Vasan, R.S. (Ramachandran Srini), Veronesi, G. (Giovanni), Völzke, H. (Henry), Waldeyer, C. (Christoph), Wannamethee, S.G. (Goya), Whincup, P.H. (Peter), Wild, P.S. (Philipp), Wilsgaard, T. (Tom), Woodward, M. (Mark), Zeller, T. (Tanja)   +86 more
core   +10 more sources

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

Association of apolipoproteins C-I, C-II, C-III and E with coagulation markers and venous thromboembolism risk

Clinical Epidemiology, 2019
Fernanda A Orsi,1,2 Willem M Lijfering,2,3 Arnoud Van der Laarse,4,5 L Renee Ruhaak,4 Frits R Rosendaal,2 Suzanne C Cannegieter,2–3,6 Christa Cobbaert41Department of Clinical Pathology, School of Medical Sciences, University of ...
Orsi FA, Lijfering WM, Van der Laarse A, Ruhaak LR, Rosendaal FR, Cannegieter SC, Cobbaert C   +6 more
doaj  

Structural studies of Manduca sexta lipid transfer particle with apolipoprotein-specific antibodies

Journal of Lipid Research, 1995
Studies have been conducted to characterize structural and functional properties of Manduca sexta lipid transfer particle (LTP). LTP is a high molecular weight complex of three apolipoproteins and lipid that facilitates the transfer of lipids between ...
B J Blacklock, R O Ryan
doaj   +1 more source

Multi‐omics data mining combined with experimental validation reveals ferroptosis‐ and autophagy‐associated hub genes as diagnostic candidates and immune modulators in atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
Using the GSE225650 dataset, we performed differential expression gene (DEG) screening, Weighted Gene Coexpression Network Analysis (WGCNA), and immune infiltration profiling on atherosclerosis (AS) samples, yielding 104 shared candidate genes. Subsequently, these 104 candidate genes were intersected with ferroptosis‑ and autophagy‑related gene sets ...
Xinou Zheng, Jinling Zheng, Xuezhuang Li, Hua Chen, Li Zhang, Yuqiong Zhao, Yahao Ling   +6 more
wiley   +1 more source

ApoA-IV metabolism in the rat: role of lipoprotein lipase and apolipoprotein transfer.

Journal of Lipid Research, 1990
Factors influencing the association of apoA-IV with high density lipoproteins (HDL) were investigated by employing a crossed immunoelectrophoresis assay to estimate the distribution of rat plasma apoA-IV between the lipoprotein-free and HDL fractions ...
M Lefevre, M Y Chuang, P S Roheim
doaj   +1 more source